Bromhexine Pharmacology

Bromhexine

About Bromhexine

Mucolytic (secretolytic)

Mechanism of Action of Bromhexine

Bromhexine hydrochloride acts as a mucokinetic and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and network of fibres in tenacious sputum is broken. It induces thin copious bronchial secretion.

Pharmacokinets of Bromhexine

Absorption: Bromhexine hydrochloride is rapidly absorbed from the gastrointestinal tract and bioavailability is about 20%. Distribution: It is widely distributed to body tissues in a highly protein bound form; Bromhexine crosses the blood brain barrier and small amounts cross the placenta, Metabolism: It undergoes extensive first-pass metabolism in the liver. Excretion: It is excreted primarily in the urine mainly as metabolites.

Onset of Action for Bromhexine

N/A

Duration of Action for Bromhexine

N/A

Half Life of Bromhexine

12hours.

Side Effects of Bromhexine

1 Rhinorrhoea
2 Lacrimations
3.Allergic reactions
4.Gastric irritation.

Contra-indications of Bromhexine

Hypersensitivity to the drug.

Special Precautions while taking Bromhexine

1. Hepatic impairment
2. Renal impairment
3. Gastric and duodenal ulcer
4. Convulsive disorders

Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Use with caution

Indications for Bromhexine

1. As Expectorant and mucolytic
2. Conditions associated with production of viscid mucous
3. Bronchitis
4. Pharyngitis
5. Laryngitis
6. Rhinitis
7. Sinusitis
8. Asthmatic bronchitis
9. Mucous bronchiectasis
10.Chronic Pneumonia.

Interactions for Bromhexine

N/A

Typical Dosage for Bromhexine

Oral: 8mg thrice daily.
Children (5 to 10 years): 4mg thrice daily
Children (1 to 5 years): 4mg twice daily.

Schedule of Bromhexine

Storage Requirements for Bromhexine

Store in a cool dry place and protect from light. Keep out of reach of children.

Effects of Missed Dosage of Bromhexine

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Bromhexine

Provide symptomatic treatment and supportive measures.

Home Delivery for Bromhexine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including bromhexine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for bromhexine and other medicines and health products. Home delivery services for bromhexine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take bromhexine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for bromhexine before they complete the sale. You can get this information while placing the order for bromhexine with the pharmacy.

Bromhexine is a generic medicine name and there are several brands available for it. Some of the brands for bromhexine might be better known than bromhexine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have bromhexine in stock, you can ask for one of the branded alternatives for bromhexine.