Thiothixene Pharmacology

Thiothixene

About Thiothixene
First-Generation Antipsychotic, a thioxanthene derivative, Typical Antipsychotic.
Mechanism of Action of Thiothixene
Thiothixene exerts its antipsychotic action by postsynaptic blockade of CNS Dopamine receptors. Thereby it inhibits Dopamine mediated effects.
Pharmacokinets of Thiothixene
Absorption:It is rapidly absorbed after oral administration.Distribution:It is widely distributed in the body in protein bound form.Metabolism:It undergoes metabolism in the liver.Excretion:Excreted mainly in the liver.
Onset of Action for Thiothixene
10- 30 minutes
Duration of Action for Thiothixene
N/A
Half Life of Thiothixene
N/A
Side Effects of Thiothixene
1.Drowsiness
2.Dizziness
3.Tardive dyskinesia
4.Hypotension
5.Tachycardia
6.Ocular changes
7.Blurred vision
8.Nasal congestion
9.Dry mouth
10.Constipation
11.Urine retention
12.Gynecomastia
13.Photosensitivity
14.Weight gain


Contra-indications of Thiothixene
1.Hypersensitivity to Thiothixene
2.Circulatory collapse
3.CNS depression
4.Blood dyscrasia
Special Precautions while taking Thiothixene
1.Seizure disorders
2.Cardiovascular diseases
3.Glaucoma
4.Prostatic hyperplasia
5.Alcohol withdrawal
Pregnancy Related Information
contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
N/A
Children Related Information
below 12 years: contraindicated
Indications for Thiothixene
1.Psychoses
Interactions for Thiothixene
N/A
Typical Dosage for Thiothixene
Mild to Moderate Psychose: 6mg/day in 3 divided doses and dose can be gradually increased to 15mg/day
Severe Psychose: 10mg/day in 2 divided doses and dose can be gradually increased to 20-30mg/day.Maximum dose: 60mg/day
Schedule of Thiothixene
N/A
Storage Requirements for Thiothixene
Store at 15 - 30 degree C. Keep out of the reach of children
Effects of Missed Dosage of Thiothixene
Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.
Effects of Overdose of Thiothixene
Give supportive measures and treatment.

Home Delivery for Thiothixene in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including thiothixene.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for thiothixene and other medicines and health products. Home delivery services for thiothixene may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take thiothixene only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for thiothixene before they complete the sale. You can get this information while placing the order for thiothixene with the pharmacy.

Thiothixene is a generic medicine name and there are several brands available for it. Some of the brands for thiothixene might be better known than thiothixene itself. If the pharmacy that's willing to deliver medicines to your home doesn't have thiothixene in stock, you can ask for one of the branded alternatives for thiothixene.