Tianeptine Pharmacology

Tianeptine

About Tianeptine
A selective serotonin reuptake enhancer (SSRE), A neuroprotective antidepressant.
Mechanism of Action of Tianeptine
Tianeptine preferentially enhance the re-uptake of Serotonin (5 HT) in the pre synaptic nerve terminals. It increase the re uptake of Serotonin in the brain and reduces stress induced atrophy of neuronal dendrites. It decreases extra cellular Serotonin level and reveals no affinity for neurotransmitter receptor. It is an antidepressant agent with a novel neurochemical profile.
Pharmacokinets of Tianeptine
Absorption: Tianeptine is rapidly absorbed after oral administration.
Metabolism: It is rapidly metabolised in the liver.
Excretion: It is excreted mainly in the urine.
Onset of Action for Tianeptine
N/A
Duration of Action for Tianeptine
N/A
Half Life of Tianeptine
2.5 hours
Side Effects of Tianeptine
1. Headache
2. Sedation
3. Nausea
4. Vomiting
5. Myalgia
6. Flatulence
7. Dry mouth
8. Drowsiness
9. Tremor
10. Epigastric pain
11. Anorexia
12. Back pain
13. Asthenia
Contra-indications of Tianeptine
Patient on Monoamine oxidase inhibitor (MAOI) therapy.
Special Precautions while taking Tianeptine
1. Anaesthesia
2. Patient at high risk for suicidal tendencies
3. Use caution while driving vehicle, operating machines and activities requiring mental alertness
4. Slowly withdraw the drug with caution

Pregnancy Related Information
Contraindicated.
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated.
Children Related Information
Contraindicated
NEONATES: Contraindicated
Indications for Tianeptine
Depression.
Interactions for Tianeptine
N/A
Typical Dosage for Tianeptine
Adult:
12.5 mg 3 times daily before meals

Schedule of Tianeptine
H
Storage Requirements for Tianeptine
Store at 15 - 30 degree C in a tightly closed container. Protect from excess heat and light.
Effects of Missed Dosage of Tianeptine
Take the missed dose as soon as noticed. If it is the time to take the next dose then skip the missed dose and take that dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Tianeptine
Give supportive measures and treatment.

Home Delivery for Tianeptine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including tianeptine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for tianeptine and other medicines and health products. Home delivery services for tianeptine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take tianeptine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for tianeptine before they complete the sale. You can get this information while placing the order for tianeptine with the pharmacy.

Tianeptine is a generic medicine name and there are several brands available for it. Some of the brands for tianeptine might be better known than tianeptine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have tianeptine in stock, you can ask for one of the branded alternatives for tianeptine.