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- Pharmacology For Eicosapentaenoic Acid
Eicosapentaenoic Acid Pharmacology
Eicosapentaenoic Acid
About Eicosapentaenoic AcidAn omega-3 fatty acid, Essential fatty acid, dietary supplement, Anti atherosclerotic.Mechanism of Action of Eicosapentaenoic AcidEicosapentaenoic acid is an omega-3 fatty acid. It is found with Docosapentaenoic acid. Omega-3 fatty acids are of polyunsaturated fatty acids that derives from food. They help to lower triglycerides and cholesterol and increase HDL cholesterol (the Good cholesterol) and thus improves lipid profile. Omega 3 fatty acids may also act as an anticoagulant to prevent blood clotting. They have anti-inflammatory actions and also lower high blood pressure. The incorporation of Omega-3 fatty acids in the membranes of the cells increases the physicochemical stability and functional integrity. It also makes the cells less susceptible to oxidative damage and also decreases the formation of lipid peroxidases. They protect from cardiovascular disorders and may also reduce the risks and symptoms for other disorders including diabetes, dementia, rheumatoid arthritis, asthma, stroke, inflammatory bowel disease, ulcerative colitis, mental decline, and some cancers. They aid in proper functioning of central nervous system.
Hypolipidaemic action: It produces a reduction in plasma triglycerides by reducing bad cholesterol or very low density lipoproteins.
Antiinflammatory action: Omega - 3 fatty acids are long chain poly unsaturated fatty acids.They compete with arachidonic acid for cyclo-oxygenase and lipoxygenase They inhibits inflammatory mediators by inhibiting leukotriene synthesis pathway.
Antithrombotic effect: They promote vasodilatation, a reduction in platelet aggregation, increased bleeding time and decreased platelet counts
Pharmacokinets of Eicosapentaenoic AcidN/AOnset of Action for Eicosapentaenoic AcidN/ADuration of Action for Eicosapentaenoic AcidN/AHalf Life of Eicosapentaenoic AcidN/ASide Effects of Eicosapentaenoic Acid1.Loose stools
2.Abdominal discomfort
3.Belching
4.Prolong bleeding time slightly
5.Nausea
6.Vomiting
7.DiarrhoeaContra-indications of Eicosapentaenoic AcidHypersensitivity to the drugSpecial Precautions while taking Eicosapentaenoic Acid1.Haemorrhagic disorders
2.Patient on anticoagulants therapy
3.Hepatic impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
Infants:ContraindicatedIndications for Eicosapentaenoic Acid1.Coronary artery disease
2.Hypertension
3.Atherosclerosis related disorders
4.Obesity
5.Fatty diet
6.Hyperlipidaemia
7.Smoking
8.Diabetes
Interactions for Eicosapentaenoic AcidN/ATypical Dosage for Eicosapentaenoic Acid180mg once or twice dailySchedule of Eicosapentaenoic AcidN/AStorage Requirements for Eicosapentaenoic AcidStore in airtight containers. Protect from light.
Effects of Missed Dosage of Eicosapentaenoic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Eicosapentaenoic AcidGive supportive measures and symptomatic treatment.Home Delivery for Eicosapentaenoic Acid in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including eicosapentaenoic acid.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for eicosapentaenoic acid and other medicines and health products. Home delivery services for eicosapentaenoic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take eicosapentaenoic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for eicosapentaenoic acid before they complete the sale. You can get this information while placing the order for eicosapentaenoic acid with the pharmacy.
Eicosapentaenoic Acid is a generic medicine name and there are several brands available for it. Some of the brands for eicosapentaenoic acid might be better known than eicosapentaenoic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have eicosapentaenoic acid in stock, you can ask for one of the branded alternatives for eicosapentaenoic acid.