Olmesartan Pharmacology

Olmesartan

About Olmesartan
An angiotensin II receptor antagonist, Imidazole derivative, Antihypertensive.
Mechanism of Action of Olmesartan
Olmesartan is a competitive antagonist of angiotensin-II at AT-1 receptor. It decreases peripheral resistance and lowers BP in hypertensive individuals. It blocks all overt actions of angiotensin-II such as: - Vasoconstriction, Central & Peripheral sympathetic stimulus, Release of aldosterone and adrenaline, Salt and water reabsorption and Central actions like thirst, vasopressin release, and growth promoting actions on heart and blood vessels and at last produces lowering of blood pressure.
Pharmacokinets of Olmesartan
Absorption: It is rapidly and completely absorbed after oral administration.
Metabolism: It undergoes metabolism in the liver.
Excretion: It is excreted primarily in urine and small amount in urine.
Onset of Action for Olmesartan
N/A
Duration of Action for Olmesartan
N/A
Half Life of Olmesartan
13 hours
Side Effects of Olmesartan
1.Dizziness
2.Headache
3.Diarrhea
4.Upper respiratory tract infection
5.Abnormal heart rate
6.Chest pain
7.Peripheral edema
8.Vertigo
9.Abdominal pain
10.Dyspepsia
11.Nausea
12.Hypercholesterolemia
13.Hyperuricemia
14.Arthralgia
15.Arthritis
16.Myalgia
17.Rash
18.Facial edema
Contra-indications of Olmesartan
Hypersensitivity to Olmesartan
Special Precautions while taking Olmesartan
1.Renal impairment
2.Renal artery stenosis
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Contraindicated
Indications for Olmesartan
Hypertension
Interactions for Olmesartan
N/A
Typical Dosage for Olmesartan
Adult: 20mg/day and if needed dose can be increased to 40mg/day
Schedule of Olmesartan
N/A
Storage Requirements for Olmesartan
Store at 20 - 25 degree C. Keep out of the reach of children. Keep away from heat, light and moisture.
Effects of Missed Dosage of Olmesartan
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Olmesartan
Give supportive measures and symptomatic treatment.

Home Delivery for Olmesartan in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including olmesartan.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for olmesartan and other medicines and health products. Home delivery services for olmesartan may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take olmesartan only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for olmesartan before they complete the sale. You can get this information while placing the order for olmesartan with the pharmacy.

Olmesartan is a generic medicine name and there are several brands available for it. Some of the brands for olmesartan might be better known than olmesartan itself. If the pharmacy that's willing to deliver medicines to your home doesn't have olmesartan in stock, you can ask for one of the branded alternatives for olmesartan.