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- Pharmacology For Diethylcarbamazine + Chlorpheniramine maleate
Diethylcarbamazine + Chlorpheniramine maleate Pharmacology
Diethylcarbamazine + Chlorpheniramine maleate
About Diethylcarbamazine + Chlorpheniramine maleateN/AMechanism of Action of Diethylcarbamazine + Chlorpheniramine maleateN/APharmacokinets of Diethylcarbamazine + Chlorpheniramine maleateN/AOnset of Action for Diethylcarbamazine + Chlorpheniramine maleateN/ADuration of Action for Diethylcarbamazine + Chlorpheniramine maleateN/AHalf Life of Diethylcarbamazine + Chlorpheniramine maleateN/ASide Effects of Diethylcarbamazine + Chlorpheniramine maleateN/AContra-indications of Diethylcarbamazine + Chlorpheniramine maleateN/ASpecial Precautions while taking Diethylcarbamazine + Chlorpheniramine maleateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Diethylcarbamazine + Chlorpheniramine maleateN/AInteractions for Diethylcarbamazine + Chlorpheniramine maleateN/ATypical Dosage for Diethylcarbamazine + Chlorpheniramine maleateN/ASchedule of Diethylcarbamazine + Chlorpheniramine maleateN/AStorage Requirements for Diethylcarbamazine + Chlorpheniramine maleateN/AEffects of Missed Dosage of Diethylcarbamazine + Chlorpheniramine maleateN/AEffects of Overdose of Diethylcarbamazine + Chlorpheniramine maleateN/ADiethylcarbamazine
About DiethylcarbamazineAntiparasitic agents, Piperazines derivative, Antihelminthic agent, Filaricides.Mechanism of Action of DiethylcarbamazineThe drug exerts its action by altering micro filarial membrane which leads to their phagocytosis by tissue fixed monocytes of host. It also has an effect on muscular activity of micro filaria & adult worms causing hyperpolarisation and eventually they are dislodged.Pharmacokinets of DiethylcarbamazineAbsorption: It is absorbed orally.Distribution: Widely distributed.Metabolism: Metabolized by liver.
Excretion: Excreted through urine.
Onset of Action for Diethylcarbamazine1hourDuration of Action for Diethylcarbamazine12 hourHalf Life of Diethylcarbamazine4 to 12 hoursSide Effects of Diethylcarbamazine1. Anorexia
2. Nausea
3. Vomiting
4. Headache
5. Drowsiness
6. Myalgia
7. Arthralgia
8. Rashes
9. Fever
10. Tachycardia
11. Lymphadenopathy
Contra-indications of Diethylcarbamazine1. In Renal impairment
2. In Cardio vascular diseases
3. In debilitating individuals
4. In hypersensitivity to the drug
Special Precautions while taking Diethylcarbamazine1. Starts with a smaller dose & then increase to therapeutic dose for avoiding allergic manifestation
2. Use with caution in poor health individuals
3. Use with caution in renal diseases
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationNEONATES : ContraindicatedIndications for Diethylcarbamazine1. Filariasis
2. Filarial prophylaxis
3. Tropical eosinophilia
4. In larva migrans
Interactions for DiethylcarbamazineN/ATypical Dosage for DiethylcarbamazineStarts with 1mg/kg on first day. Then 2mg/kg 8hourly for 1 to 3 weeks
The course may be repeated after 6 months.
In larva migrans: 3mg/kg/day for 3 weeks
For prophylaxis:0.3g/week.
Schedule of DiethylcarbamazineHStorage Requirements for DiethylcarbamazineStore at 15 - 30 degree C in a tightly closed container. Keep out of the reach of children.Effects of Missed Dosage of DiethylcarbamazineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DiethylcarbamazineIn allergic manifestations due to the drug stops the drug and administer antihistaminics and glucocorticoids. Subsequent administration does not cause such reactions.Chlorpheniramine Maleate
About Chlorpheniramine MaleateN/AMechanism of Action of Chlorpheniramine MaleateN/APharmacokinets of Chlorpheniramine MaleateN/AOnset of Action for Chlorpheniramine MaleateN/ADuration of Action for Chlorpheniramine MaleateN/AHalf Life of Chlorpheniramine MaleateN/ASide Effects of Chlorpheniramine MaleateN/AContra-indications of Chlorpheniramine MaleateFirst Generation alkylamine H1 Antagonist, Antihistamine.Special Precautions while taking Chlorpheniramine MaleateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Chlorpheniramine MaleateN/AInteractions for Chlorpheniramine MaleateN/ATypical Dosage for Chlorpheniramine MaleateN/ASchedule of Chlorpheniramine MaleateN/AStorage Requirements for Chlorpheniramine MaleateN/AEffects of Missed Dosage of Chlorpheniramine MaleateN/AEffects of Overdose of Chlorpheniramine MaleateN/AHome Delivery for Diethylcarbamazine + Chlorpheniramine maleate in Your City
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