Niclosamide Pharmacology

Niclosamide

About Niclosamide
Anthelmintic, a chlorinated salicylanilide, Anticestodal(taeniacide).
Mechanism of Action of Niclosamide
It excerts its vermicidal action against cestodes by inhibiting anaerobic phosphorylation of ADP by mitochondria of parasite which leads to energy depletion. The injured worms are partially digested in the intestine.
Pharmacokinets of Niclosamide
Absorption: It is absorbed minimally from the intestine.
Onset of Action for Niclosamide
N/A
Duration of Action for Niclosamide
N/A
Half Life of Niclosamide
N/A
Side Effects of Niclosamide
1.Nausea
2.Vomiting
3.Diarrhoea
4.Headache
5.Dizziness
6.Drowsiness
7.Anorexia
8.Abdominal discomfort
9.Rashes
10.Itching
11.Pruritis
12.Light headedness
Contra-indications of Niclosamide
1. Hypersensitivity to the drug
Special Precautions while taking Niclosamide
1.Taenia solium infestation
Pregnancy Related Information
Use with caution.
Old Age Related Information
May be used.
Breast Feeding Related Information
Use with caution.
Children Related Information
Above 2 years: May be used
Neonates : Contraindicated





Indications for Niclosamide
1.Taenia saginata
2.Diphyllobothrium latum
3.Hymenolepis nana
4.Taenia solium
Interactions for Niclosamide
N/A
Typical Dosage for Niclosamide
Adults: Chew 1gm tablet in empty stomach with water. Another 1gm is given after 1 hour. A saline purgative is given 1 to 2hour after second dose.
In H. nana dosage is repeated for 5days.
Children (2 to 6years): 1gm/day
Schedule of Niclosamide
N/A
Storage Requirements for Niclosamide
Store in a cool dry place.Protect from heat and light. Keep out of the reach of children.
Effects of Missed Dosage of Niclosamide
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Niclosamide
Give supportive measures and symptomatic treatment.

Home Delivery for Niclosamide in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including niclosamide.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for niclosamide and other medicines and health products. Home delivery services for niclosamide may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take niclosamide only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for niclosamide before they complete the sale. You can get this information while placing the order for niclosamide with the pharmacy.

Niclosamide is a generic medicine name and there are several brands available for it. Some of the brands for niclosamide might be better known than niclosamide itself. If the pharmacy that's willing to deliver medicines to your home doesn't have niclosamide in stock, you can ask for one of the branded alternatives for niclosamide.