Sodium Antimony Gluconate Pharmacology

Sodium Antimony Gluconate

About Sodium Antimony Gluconate
Antimony compound, Anti protozoal,antileishmanial.
Mechanism of Action of Sodium Antimony Gluconate
Sodium stibogluconate is a pentavalent antimonial which is the drug of choice for kala-azar. The exact mechanism of action and selective toxicity to the parasite is unclear. The drug inhibits the SH group containing enzymes of parasite & affects the bioenergetics of the parasite. It blocks the glycolytic & fatty acid oxidation pathways
Pharmacokinets of Sodium Antimony Gluconate
Well absorbed after I.M. administration Distribution: A small portion enters tissues and stored for long periods, Metabolism: It is not metabolized inside the body, Excretion: Excreted through urine
Onset of Action for Sodium Antimony Gluconate
N/A
Duration of Action for Sodium Antimony Gluconate
N/A
Half Life of Sodium Antimony Gluconate
6 to 12 hours
Side Effects of Sodium Antimony Gluconate
1.Nausea
2.Myalgia
3.Pain at injection site
4.Cough
5.Loss of appetite
6.Headache
7.Abdominal pain
8.Tiredness
9.ECG changes
10.Anaphylactic shock
11.Vomiting
12.Diarrhoea.
Contra-indications of Sodium Antimony Gluconate
1.Nephritis and Renal impairment
2.Hypersensitivity to the drug
3.Jaundice
4.Cirrhosis
Special Precautions while taking Sodium Antimony Gluconate
1.Hepatic impairment
2.Cardiovascular disorders
3.Local skin inflammation
4.Concurrent infections such as pneumonia should be treated,
5.Stop I.V. when coughing or chest pain
Pregnancy Related Information
Contraindicated
Old Age Related Information
N/A
Breast Feeding Related Information
Contraindicated
Children Related Information
N/A
Indications for Sodium Antimony Gluconate
1.Cutaneous & Visceral leishmaniasis
Interactions for Sodium Antimony Gluconate
N/A
Typical Dosage for Sodium Antimony Gluconate
Sodium antimony gluconate 0.33gm equivalent to total antimony 100mg, cresol 0.3% w/v
Adults:
4 to6 gm for full course
10 to 20mg/kg/day I.M. or I.V. (infusion over 5 minutes) for 20 to 30 days
Maximum dose: 850mg/day
Schedule of Sodium Antimony Gluconate
H
Storage Requirements for Sodium Antimony Gluconate
Store at 15 - 30 degree C in a tightly closed container. Keep out of the reach of children.
Effects of Missed Dosage of Sodium Antimony Gluconate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sodium Antimony Gluconate
Give supportive measures and symptomatic treatment.

Home Delivery for Sodium Antimony Gluconate in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sodium antimony gluconate and other medicines and health products. Home delivery services for sodium antimony gluconate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sodium antimony gluconate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sodium antimony gluconate before they complete the sale. You can get this information while placing the order for sodium antimony gluconate with the pharmacy.

Sodium Antimony Gluconate is a generic medicine name and there are several brands available for it. Some of the brands for sodium antimony gluconate might be better known than sodium antimony gluconate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sodium antimony gluconate in stock, you can ask for one of the branded alternatives for sodium antimony gluconate.