- Medicine India
- Generic Medicines
- D
- Pharmacology For Dextrose 5% + NaCl 0.45%
Dextrose 5% + NaCl 0.45% Pharmacology
Dextrose 5% + NaCl 0.45%
About Dextrose 5% + NaCl 0.45%N/AMechanism of Action of Dextrose 5% + NaCl 0.45%N/APharmacokinets of Dextrose 5% + NaCl 0.45%N/AOnset of Action for Dextrose 5% + NaCl 0.45%N/ADuration of Action for Dextrose 5% + NaCl 0.45%N/AHalf Life of Dextrose 5% + NaCl 0.45%N/ASide Effects of Dextrose 5% + NaCl 0.45%N/AContra-indications of Dextrose 5% + NaCl 0.45%N/ASpecial Precautions while taking Dextrose 5% + NaCl 0.45%N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Dextrose 5% + NaCl 0.45%N/AInteractions for Dextrose 5% + NaCl 0.45%N/ATypical Dosage for Dextrose 5% + NaCl 0.45%N/ASchedule of Dextrose 5% + NaCl 0.45%N/AStorage Requirements for Dextrose 5% + NaCl 0.45%N/AEffects of Missed Dosage of Dextrose 5% + NaCl 0.45%N/AEffects of Overdose of Dextrose 5% + NaCl 0.45%N/ADextrose 5%
About Dextrose 5%Intravenous injection / parenteral nutrient, a solution of Dextrose 5% in Water, Carbohydrate caloric nutritional supplement and fluid replenishment.Mechanism of Action of Dextrose 5%Dextrose restores blood glucose levels in hypoglycemia and provides a source of carbohydrate calories after IV injection. It decreases losses of body protein and nitrogen, promotes glycogen deposition, and prevents ketosis. It reverses CNS effects of hypoglycemia by rapidly increasing serum glucose levels.
Dextrose injection undergoes oxidation to carbon dioxide and water. Water is an essential constituent of all body tissues Average normal adult requirement ranges from two to three liters. Water balance is maintained by various regulatory mechanisms. Water distribution depends primarily on the concentration of electrolytes in the body compartments.
Pharmacokinets of Dextrose 5%Absorption: It is well absorbed after parenteral administration.Onset of Action for Dextrose 5%N/ADuration of Action for Dextrose 5%N/AHalf Life of Dextrose 5%N/ASide Effects of Dextrose 5%1.Fluid and electrolyte imbalances (((Hypokalemia and dehydration)))
2.Hyperglycaemia
3.Hyperosmotic syndrome (((mental confusion and loss of consciousness)))
4.Reactive hypoglycemia
5.Infection at the site of injection
6.Venous thrombosis
7.Extravasation
8.Hypervolemia.
Contra-indications of Dextrose 5%1.Hypersensitivity to dextrose solution, corn or corn products
2.Diabetic coma while patient is hyperglycemic
3.Intracranial haemorrhage
4.In the presence of delirium in dehydrated patients.
Special Precautions while taking Dextrose 5%1.Diabetes mellitus
2.Ischemic stroke
3.Hypervolemia
4.Renal impairment
5,Urinary tract obstruction
6.Essential electrolytes, minerals, and vitamins should be supplied if needed
7.Potassium should be added to dextrose solutions administered to fasting patients with good renal function, especially those on digitalis therapy
8. Do not administer D50W if there is any doubt about IV patency.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: contraindicatedIndications for Dextrose 5%1. Prevention of: dehydration, excessive tissue protein catabolism, depletion of liver glycogen
2. As vehicle for IV numerous drugs
3. Provide calorie in preoperative and post operative patients, patient with severe hepatic, cardiac or gastric disease
4. Source of water in inadequate water intake and excessive water loses
5. Treatment of ketosis in starvation, diarrhoea, vomiting or high fever
6. Hypernatremia
Interactions for Dextrose 5%N/ATypical Dosage for Dextrose 5%ADULT: 1.5 - 3 L/day
Maintenance therapy: 1.5-2 L/day over 8-12 hour
Maximum infusion rate: 0.85mg/kg body weight / hour
Schedule of Dextrose 5%N/AStorage Requirements for Dextrose 5%Store the drug at 15 - 30 degree C. Do not freeze.Effects of Missed Dosage of Dextrose 5%N/AEffects of Overdose of Dextrose 5%Give supportive measures and symptomatic treatment.NaCl 0.45%
About NaCl 0.45%IV solutions ;It is given along with dextrose solution, A nonpyrogenic solution for fluid and electrolyte replenishment and caloric supply.Mechanism of Action of NaCl 0.45%This solution of sodium chloride in sterile water (contains Na+ and Cl-) create an oncotic gradient for expanding plasma volume. Then a greater percentage of the infused fluid stays within the vascular space and does not leak out into the extra vascular spaces. It would be available to rapidly rehydrate the extra vascular volumes in the extracellular fluid (ECF) and intracellular fluid (ICF) spaces.
It is a nonpyrogenic solution for fluid and electrolyte replenishment and caloric supply.It is given along with dextrose solution.
0.45% Sodium Chloride Injection contains 4.5 g/L Sodium Chloride, (NaCl) with an osmolarity of 154 mOsmol/L .It contains 77 mEq/L sodium and 77 mEq/L chloride
Pharmacokinets of NaCl 0.45%N/AOnset of Action for NaCl 0.45%N/ADuration of Action for NaCl 0.45%N/AHalf Life of NaCl 0.45%N/ASide Effects of NaCl 0.45%1. Pulmonary edema
2. Febrile reactions
Contra-indications of NaCl 0.45%Contraindicated in patients with hypersensitivity to the solutionSpecial Precautions while taking NaCl 0.45%1.Severe renal insufficiency
2.Congestive heart failure
3.Do not use plastic containers in series connections
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for NaCl 0.45%1. Intravenous infusion
2. Severe salt depletion
3. Low salt syndrome which may occur in presence of heart failure, renal impairment, during surgery, etc.
4. Excessive fluid loss due to sweating, vomiting, diarrhoea, etc
Interactions for NaCl 0.45%N/ATypical Dosage for NaCl 0.45%Dose is dependent upon the age, weight and clinical condition of the patient. Schedule of NaCl 0.45%N/AStorage Requirements for NaCl 0.45%Store at room temperature (25 - 30 degree C)Effects of Missed Dosage of NaCl 0.45%N/AEffects of Overdose of NaCl 0.45%Give symptomatic and supportive treatmentHome Delivery for Dextrose 5% + NaCl 0.45% in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dextrose 5% + nacl 0.45%.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dextrose 5% + nacl 0.45% and other medicines and health products. Home delivery services for dextrose 5% + nacl 0.45% may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take dextrose 5% + nacl 0.45% only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dextrose 5% + nacl 0.45% before they complete the sale. You can get this information while placing the order for dextrose 5% + nacl 0.45% with the pharmacy.
Dextrose 5% + NaCl 0.45% is a generic medicine name and there are several brands available for it. Some of the brands for dextrose 5% + nacl 0.45% might be better known than dextrose 5% + nacl 0.45% itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextrose 5% + nacl 0.45% in stock, you can ask for one of the branded alternatives for dextrose 5% + nacl 0.45%.