Dextrose 20% Pharmacology

Dextrose 20%

About Dextrose 20%
ntravenous injection / parenteral nutrient, a solution of Dextrose 20% in Water, Carbohydrate caloric nutritional supplement and fluid replenishment.
Mechanism of Action of Dextrose 20%
Dextrose restores blood glucose levels in hypoglycemia and provides a source of carbohydrate calories after IV injection. It decreases losses of body protein and nitrogen, promotes glycogen deposition, and prevents ketosis. It reverses CNS effects of hypoglycemia by rapidly increasing serum glucose levels.
Dextrose injection undergoes oxidation to carbon dioxide and water. Water is an essential constituent of all body tissues Average normal adult requirement ranges from two to three liters. Water balance is maintained by various regulatory mechanisms. Water distribution depends primarily on the concentration of electrolytes in the body compartments.
Pharmacokinets of Dextrose 20%
Absorption: It is well absorbed after parenteral administration.
Onset of Action for Dextrose 20%
N/A
Duration of Action for Dextrose 20%
N/A
Half Life of Dextrose 20%
N/A
Side Effects of Dextrose 20%
1. Fluid and electrolyte imbalances (((Hypokalemia and dehydration)))
2.Hyperglycaemia
3.Hyperosmotic syndrome (((mental confusion and loss of consciousness)))
4.Reactive hypoglycemia
5.Infection at the site of injection
6.Venous thrombosis
7.Extravasation
8.Hypervolemia.
Contra-indications of Dextrose 20%
1. Hypersensitivity to dextrose solution, corn or corn products
2.Diabetic coma while patient is hyperglycemic
3.Intracranial haemorrhage
4.In the presence of delirium in dehydrated patients.
Special Precautions while taking Dextrose 20%
1.Diabetes mellitus
2.Ischemic stroke
3.Hypervolemia
4.Renal impairment
5.Urinary tract obstruction
6.Essential electrolytes, minerals and vitamins should be supplied if needed
7.Potassium should be added to dextrose solutions administered to fasting patients with good renal function, especially those on digitalis therapy
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Dextrose 20%
1. Severe hypoglycemia
2.As a source of carbohydrate calories
3.Severe hyperkalemia
4. Dialysis-induced muscle cramps in uraemic patients
5.To promote diuresis.
Interactions for Dextrose 20%
N/A
Typical Dosage for Dextrose 20%
N/A
Schedule of Dextrose 20%
N/A
Storage Requirements for Dextrose 20%
Store the drug at 15 - 30 degree C. Do not freeze.
Effects of Missed Dosage of Dextrose 20%
N/A
Effects of Overdose of Dextrose 20%
Give supportive measures and symptomatic treatment.

Home Delivery for Dextrose 20% in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dextrose 20%.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dextrose 20% and other medicines and health products. Home delivery services for dextrose 20% may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take dextrose 20% only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dextrose 20% before they complete the sale. You can get this information while placing the order for dextrose 20% with the pharmacy.

Dextrose 20% is a generic medicine name and there are several brands available for it. Some of the brands for dextrose 20% might be better known than dextrose 20% itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextrose 20% in stock, you can ask for one of the branded alternatives for dextrose 20%.