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- Pharmacology For Cefpodoxime + Lactobacillus
Cefpodoxime + Lactobacillus Pharmacology
Cefpodoxime + Lactobacillus
About Cefpodoxime + LactobacillusN/AMechanism of Action of Cefpodoxime + LactobacillusN/APharmacokinets of Cefpodoxime + LactobacillusN/AOnset of Action for Cefpodoxime + LactobacillusN/ADuration of Action for Cefpodoxime + LactobacillusN/AHalf Life of Cefpodoxime + LactobacillusN/ASide Effects of Cefpodoxime + LactobacillusN/AContra-indications of Cefpodoxime + LactobacillusN/ASpecial Precautions while taking Cefpodoxime + LactobacillusN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Cefpodoxime is contraindicated in breast feeding, the combination generic is contraindicated in Breast feeding mother.Children Related InformationN/AIndications for Cefpodoxime + LactobacillusCefpodoxime proxetil is indicated for the treatment of patients with mild to moderate infections caused by susceptible micro-organisms.
1.Upper and lower respiratory tract infections
2.Skin and skin structure Infections
3.Urinary tract infections (cystitis),
4.Gonorrhoea
5.Uncomplicated Ano-Rectal Infections in Women
Interactions for Cefpodoxime + LactobacillusN/ATypical Dosage for Cefpodoxime + Lactobacillus1 tablet to be taken 2 times daily.Schedule of Cefpodoxime + LactobacillusN/AStorage Requirements for Cefpodoxime + LactobacillusN/AEffects of Missed Dosage of Cefpodoxime + LactobacillusN/AEffects of Overdose of Cefpodoxime + LactobacillusN/ACefpodoxime
About CefpodoximeThird Generation Cephalosporin antibiotic, Oral antibiotic.Mechanism of Action of CefpodoximeCefpodoxime is a 3rd generation cephalosporin which exerts its bactericidal action mainly against gram positive organisms by inhibiting bacterial cell wall synthesis. Cefpodoxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefpodoxime.
It is active against enterobacteriaceae, streptococci ,staphylococci aureus, & H. influenzae.
Pharmacokinets of CefpodoximeAbsorption: Orally well absorbed &food increases absorption rate. Distribution: widely distributed, Metabolism: Its ester prodrug Cefpodoxime proxetil is deesterified in to its active metabolite Cefpodoxime in the body, Excretion: Excreted mainly through urineOnset of Action for CefpodoximeN/ADuration of Action for CefpodoximeN/AHalf Life of CefpodoximeN/ASide Effects of Cefpodoxime1.Rashes & allergic manifestation
2.Vaginitis
3.Pruritus
4.Candidiasis
5.Headache
6.Pseudo membranous colitis
7.Nausea
8.Vomiting
9.Diarrhea
10.Leucopenia
11.Thrombocytopenia
Contra-indications of Cefpodoxime1.Hypersensitivity to cephalosporinsSpecial Precautions while taking Cefpodoxime1.Renal impairment
2.Those allergic to penicillins
3.Neuromuscular disorders
4.Use cautiously along with other nephrotoxic drugs
Pregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationContraindicatedChildren Related Information(Above 6 months): may be used
Neonates: contraindicatedIndications for Cefpodoxime1.Pneumonia, bronchitis &other respiratory tract infections
2.Sinusitis
3.Urinary tract &genital tract infections
4.Gonorrhea & rectal gonococcal infections
5.Skin infections
6.Otitismedia
7.Tonsillitis, Pharyngitis
Interactions for CefpodoximeAntacids and H2 blockers : Plasma concentration of cefpodoxime proxetil may be decreased by 30%.
Probenecid : Plasma levels of cefpodoxime increased when used concomitantly.
Typical Dosage for CefpodoximeAdults: 0. 2gm twice daily.
Maximum adult dose: Up to 0.8gm/day
Children: 5mg/kg/day
Maximum child dose: 200mg/day
Pneumonia:
Adults: 0. 2gm twice daily for two weeks
Bronchitis:
Adults: 0. 2gm twice daily for 10 days
Gonorrhea:
0.2 gm single dose followed by 0.1gm doxycycline orally twice daily for a week
Pharyngitis & Tonsillitis
Adults: 0.1gm orally twice daily for 10 days
Children: 5mg/kg/day orally twice daily for 5 to 10 days
Urinary tract infections:0.1gm twice daily for a week
Otitismedia (2 to12 years old): 5mg/kg/day
Skin infections: 400mg twice daily for two weeks
Schedule of CefpodoximeHStorage Requirements for CefpodoximeN/AEffects of Missed Dosage of CefpodoximeN/AEffects of Overdose of CefpodoximeN/ALactobacillus
About LactobacillusLactic acid bacteria, Probiotic,Antidiarrhoeal.Mechanism of Action of LactobacillusLactobacillus is a probiotic and it is called as friendly bacteria. It is used along with antibiotic in order to restore the body`s natural microbial flora with in the digestive tract. Lactobacillus helps in the breakdown of food and leads to the production of lactic acid, hydrogen peroxide and other byproducts. This will alter the intestinal pH and that make the environment hostile for pathogens.Pharmacokinets of LactobacillusAbsorption: It is orally well absorbed after oral administration.
Onset of Action for LactobacillusN/ADuration of Action for LactobacillusN/AHalf Life of LactobacillusN/ASide Effects of Lactobacillus1.Abdominal discomfort
2.Vaginal irritation (when used vaginally)
Contra-indications of Lactobacillus1.Recent bowel surgery
2.Intestinal damage
3.Weakened immune system
Special Precautions while taking LactobacillusPatient on Inulin treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Use with cautionIndications for Lactobacillus1.Aphthous stomatitis
2.Hypochlorhydria
3.Hepatic encephalopathy
4.Adjuvant to antibiotic therapy
5.Diarrhoea.Interactions for LactobacillusN/ATypical Dosage for LactobacillusAdult: 60 - 150 million spores 3 times daily depending on the severity of infections.
Vaginal bacterial infections: 1- 2 billion bacteria 2 - 3 times daily
Suppositories:
Vaginal infections, cystitis: 1 - 2 suppositories are inserted in to vagina at night for 2 weeks. Each suppository contains 1 - 2 billion lactobacilli
Schedule of LactobacillusN/AStorage Requirements for LactobacillusRefrigerate below 5 degree C.Effects of Missed Dosage of LactobacillusN/AEffects of Overdose of LactobacillusGive supportive measures and symptomatic treatmentHome Delivery for Cefpodoxime + Lactobacillus in Your City
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Cefpodoxime + Lactobacillus is a generic medicine name and there are several brands available for it. Some of the brands for cefpodoxime + lactobacillus might be better known than cefpodoxime + lactobacillus itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefpodoxime + lactobacillus in stock, you can ask for one of the branded alternatives for cefpodoxime + lactobacillus.