Alpha-Lipoic Acid + Vitamins Pharmacology

Alpha-Lipoic Acid + Vitamins

About Alpha-Lipoic Acid + Vitamins

N/A

Mechanism of Action of Alpha-Lipoic Acid + Vitamins

N/A

Pharmacokinets of Alpha-Lipoic Acid + Vitamins

N/A

Onset of Action for Alpha-Lipoic Acid + Vitamins

N/A

Duration of Action for Alpha-Lipoic Acid + Vitamins

N/A

Half Life of Alpha-Lipoic Acid + Vitamins

N/A

Side Effects of Alpha-Lipoic Acid + Vitamins

N/A

Contra-indications of Alpha-Lipoic Acid + Vitamins

N/A

Special Precautions while taking Alpha-Lipoic Acid + Vitamins

N/A

Pregnancy Related Information

Use with caution

Old Age Related Information

May be used

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Alpha-Lipoic Acid + Vitamins

1.Diabetic And Peripheral Neuropathy
2.Nutritional supplement

Interactions for Alpha-Lipoic Acid + Vitamins

N/A

Typical Dosage for Alpha-Lipoic Acid + Vitamins

N/A

Schedule of Alpha-Lipoic Acid + Vitamins

N/A

Storage Requirements for Alpha-Lipoic Acid + Vitamins

N/A

Effects of Missed Dosage of Alpha-Lipoic Acid + Vitamins

N/A

Effects of Overdose of Alpha-Lipoic Acid + Vitamins

N/A

Alpha-Lipoic acid

About Alpha-Lipoic acid

Naturally occurring dithiol compound , antioxidant, Agent for neuropathies.

Mechanism of Action of Alpha-Lipoic acid

Alpha-lipoic acid and its reduced metabolite, Dihydrolipoic acid (DHLA), form a redox couple and may scavenge a wide range of reactive oxygen species. Alpha-lipoic acid has been found to decrease urinary isoprostanes, O-LDL and plasma protein carbonyls, markers of oxidative stress. Further, alpha-lipoic acid and its redox couple DHLA have been found to have antioxidant activity in aqueous, as well as in lipophilic regions, and in extra cellular and intracellular environments. Alpha-lipoic acid participates in the recycling of other important biologic antioxidants, such as vitamins E and C, Ubiquinone and glutathione.
Both alpha-lipoic acid and DHLA can scavenge hydroxyl radicals, the nitric oxide radical, peroxynitrite, hydrogen peroxide and hypochlorite. Alpha-lipoic acid may scavenge singlet oxygen, and DHLA may scavenge super oxide and peroxyl reactive oxygen species.

Pharmacokinets of Alpha-Lipoic acid

Absorption: Alpha-lipoic acid is absorbed from the small intestine. The natural R-entantiomer is more readily absorbed than the L-entantiomer and is the more active form.
Distribution:It is distributed to the liver via the portal circulation and to various tissues in the body via the systemic circulation. . Alpha-lipoic acid readily crosses the blood-brain barrier. It is found, after its distribution to the various body tissues, intracellularly, intramitochondrialy and extracellularly.Metabolism: Alpha-lipoic acid is metabolized to its reduced form, dihydrolipoic acid (DHLA), by mitochondrial lipoamide dehydrogenase enzyme. DHLA, together with lipoic acid, form a redox couple. It is also metabolized to lipoamide, which functions as the lipoic acid cofactor in the multienzyme complexes that catalyze the oxidative decarboxylations of pyruvate and alpha-ketoglutarate. Alpha-lipoic acid may be metabolized to dithiol octanoic acid, which can undergo catabolism.

Onset of Action for Alpha-Lipoic acid

N/A

Duration of Action for Alpha-Lipoic acid

N/A

Half Life of Alpha-Lipoic acid

N/A

Side Effects of Alpha-Lipoic acid

1.Nausea
2.Vomiting

Contra-indications of Alpha-Lipoic acid

1.Contraindicated during radiotherapy

Special Precautions while taking Alpha-Lipoic acid

Patient with diabetes and problems with glucose intolerance

Pregnancy Related Information

Use with caution

Old Age Related Information

N/A

Breast Feeding Related Information

Use with caution

Children Related Information

N/A

Indications for Alpha-Lipoic acid

1.Diabetic neuropathy
2.It may help prevent the oxidation of LDL cholesterol and may be protective, generally, against oxidative stress and, specifically, against atherosclerosis, ischemia-reperfusion injury and various radiologic and chemical toxins.
3.It may also be useful in some inborn metabolic disorders

Interactions for Alpha-Lipoic acid

N/A

Typical Dosage for Alpha-Lipoic acid

Adult: up to 600 milligrams daily
Diabetic neuropathy: 300 milligrams daily taken in divided doses.

Schedule of Alpha-Lipoic acid

N/A

Storage Requirements for Alpha-Lipoic acid

Store at room temperature away from moisture and heat.Keep out of the reach of children. Keep the medicine from freezing. Do not refrigerate.

Effects of Missed Dosage of Alpha-Lipoic acid

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.

Effects of Overdose of Alpha-Lipoic acid

Give supportive measures and symptomatic treatment.

Vitamins

About Vitamins

Vitamins are substances that are found in foods we eat. The term vitamin is derived from the words vital and amine, because vitamins are required for life and were originally thought to be amines. All vitamins are not amines. Vitamins are different in their chemistry, but they all are organic nutrients that are necessary in small amounts for normal metabolism and good health. Most vitamins must be provided by the diet or by supplements; only three vitamins (D, K, and the B vitamin biotin) can be manufactured in the body from non dietary sources. Vitamins are not sources of energy as are carbohydrates, fats, and proteins. Instead, vitamins serve as chemical partners for the enzymes involved in the body`s metabolism, cell production, tissue repair, and other vital processes. Vitamins serve crucial functions in almost all bodily processes example immune, hormonal and nervous systems.
In humans there are thirteen vitamins, divided into two groups. They are fat soluble and water soluble. Fat-soluble vitamins are stored in the fat tissues in your body and in your liver. They go and wait around in your body fat until your body needs them. Water-soluble vitamins are different. Water-soluble vitamins, the vitamins don`t get stored as much in body. Instead, they travel through bloodstream comes out when urinate if body don`t used it.
In humans there are thirteen vitamins, divided into two groups; four fat-soluble vitamins (A, D, E and K), and nine water-soluble vitamins (eight B vitamins and vitamin C).

Mechanism of Action of Vitamins

N/A

Pharmacokinets of Vitamins

N/A

Onset of Action for Vitamins

N/A

Duration of Action for Vitamins

N/A

Half Life of Vitamins

N/A

Side Effects of Vitamins

N/A

Contra-indications of Vitamins

N/A

Special Precautions while taking Vitamins

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Vitamins

N/A

Interactions for Vitamins

N/A

Typical Dosage for Vitamins

N/A

Schedule of Vitamins

N/A

Storage Requirements for Vitamins

N/A

Effects of Missed Dosage of Vitamins

N/A

Effects of Overdose of Vitamins

N/A

Home Delivery for Alpha-Lipoic Acid + Vitamins in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including alpha-lipoic acid + vitamins.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for alpha-lipoic acid + vitamins and other medicines and health products. Home delivery services for alpha-lipoic acid + vitamins may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take alpha-lipoic acid + vitamins only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for alpha-lipoic acid + vitamins before they complete the sale. You can get this information while placing the order for alpha-lipoic acid + vitamins with the pharmacy.

Alpha-Lipoic Acid + Vitamins is a generic medicine name and there are several brands available for it. Some of the brands for alpha-lipoic acid + vitamins might be better known than alpha-lipoic acid + vitamins itself. If the pharmacy that's willing to deliver medicines to your home doesn't have alpha-lipoic acid + vitamins in stock, you can ask for one of the branded alternatives for alpha-lipoic acid + vitamins.