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- Pharmacology For Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + Zinc
Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + Zinc Pharmacology
Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + Zinc
About Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AMechanism of Action of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/APharmacokinets of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AOnset of Action for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/ADuration of Action for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AHalf Life of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/ASide Effects of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AContra-indications of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/ASpecial Precautions while taking Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationUse with cautionIndications for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + Zinc1.Disturbed intestinal Flora
2.Along with anti-biotic Therapy
3.Along with iron therapy
4.Co-prescription with Anti-cholesterol drugs as an adjunctive therapy in Hyperlipidaemia
Interactions for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/ATypical Dosage for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/ASchedule of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AStorage Requirements for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AEffects of Missed Dosage of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/AEffects of Overdose of Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + ZincN/ALactobacillus
About LactobacillusLactic acid bacteria, Probiotic,Antidiarrhoeal.Mechanism of Action of LactobacillusLactobacillus is a probiotic and it is called as friendly bacteria. It is used along with antibiotic in order to restore the body`s natural microbial flora with in the digestive tract. Lactobacillus helps in the breakdown of food and leads to the production of lactic acid, hydrogen peroxide and other byproducts. This will alter the intestinal pH and that make the environment hostile for pathogens.Pharmacokinets of LactobacillusAbsorption: It is orally well absorbed after oral administration.
Onset of Action for LactobacillusN/ADuration of Action for LactobacillusN/AHalf Life of LactobacillusN/ASide Effects of Lactobacillus1.Abdominal discomfort
2.Vaginal irritation (when used vaginally)
Contra-indications of Lactobacillus1.Recent bowel surgery
2.Intestinal damage
3.Weakened immune system
Special Precautions while taking LactobacillusPatient on Inulin treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Use with cautionIndications for Lactobacillus1.Aphthous stomatitis
2.Hypochlorhydria
3.Hepatic encephalopathy
4.Adjuvant to antibiotic therapy
5.Diarrhoea.Interactions for LactobacillusN/ATypical Dosage for LactobacillusAdult: 60 - 150 million spores 3 times daily depending on the severity of infections.
Vaginal bacterial infections: 1- 2 billion bacteria 2 - 3 times daily
Suppositories:
Vaginal infections, cystitis: 1 - 2 suppositories are inserted in to vagina at night for 2 weeks. Each suppository contains 1 - 2 billion lactobacilli
Schedule of LactobacillusN/AStorage Requirements for LactobacillusRefrigerate below 5 degree C.Effects of Missed Dosage of LactobacillusN/AEffects of Overdose of LactobacillusGive supportive measures and symptomatic treatmentFructo-oligosaccharides
About Fructo-oligosaccharidesOligosaccharide, Dietary supplement, Prebiotic, an artificial or alternative sweetener.Mechanism of Action of Fructo-oligosaccharidesN/APharmacokinets of Fructo-oligosaccharidesN/AOnset of Action for Fructo-oligosaccharidesN/ADuration of Action for Fructo-oligosaccharidesN/AHalf Life of Fructo-oligosaccharidesN/ASide Effects of Fructo-oligosaccharidesN/AContra-indications of Fructo-oligosaccharidesN/ASpecial Precautions while taking Fructo-oligosaccharidesN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Fructo-oligosaccharidesN/AInteractions for Fructo-oligosaccharidesN/ATypical Dosage for Fructo-oligosaccharidesN/ASchedule of Fructo-oligosaccharidesN/AStorage Requirements for Fructo-oligosaccharidesN/AEffects of Missed Dosage of Fructo-oligosaccharidesN/AEffects of Overdose of Fructo-oligosaccharidesN/AFolic Acid
About Folic AcidDietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.Mechanism of Action of Folic AcidFolic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.Pharmacokinets of Folic AcidAbsorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic AcidOral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic AcidOral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic AcidN/ASide Effects of Folic AcidN/AContra-indications of Folic AcidN/ASpecial Precautions while taking Folic Acid1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Folic Acid1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic AcidOral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic AcidC1 (Oral)
C (Parenteral)
Storage Requirements for Folic AcidStore at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.Effects of Missed Dosage of Folic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Folic AcidRelatively non toxic. Provide symptomatic treatment and supportive measures.About N/AMechanism of Action of N/APharmacokinets of N/AOnset of Action for N/ADuration of Action for N/AHalf Life of N/ASide Effects of N/AContra-indications of N/ASpecial Precautions while taking N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for N/AInteractions for N/ATypical Dosage for N/ASchedule of N/AStorage Requirements for N/AEffects of Missed Dosage of N/AEffects of Overdose of N/AZinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresHome Delivery for Lactobacillus + Fructo-Oligosaccharides + Folic Acid + Vitamin B12 + Zinc in Your City
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