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- Pharmacology For Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + Carotenoids
Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + Carotenoids Pharmacology
Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + Carotenoids
About Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AMechanism of Action of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/APharmacokinets of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AOnset of Action for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/ADuration of Action for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AHalf Life of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/ASide Effects of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AContra-indications of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/ASpecial Precautions while taking Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + Carotenoids1.Nutritional supplement
2.Antioxidant
3.Cardiovascular and neuronal diseases
Interactions for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/ATypical Dosage for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/ASchedule of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AStorage Requirements for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AEffects of Missed Dosage of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/AEffects of Overdose of Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + CarotenoidsN/ADocosahexenoic Acid
About Docosahexenoic AcidAn omega-3 fatty acid(polyunsaturated fatty acids, PUFAs), An essential fatty acid, brain food ,Antiatherosclerotic.Mechanism of Action of Docosahexenoic AcidIt is found with Eicosapentaenoic acid. Omega-3 fatty acids are of polyunsaturated fatty acids that derives from food. They help to lower triglycerides and cholesterol and increase HDL cholesterol (the Good cholesterol) and thus improves lipid profile. Omega 3 fatty acids may also act as an anticoagulant to prevent blood clotting. They have anti-inflammatory actions and also lower high blood pressure. The incorporation of Omega-3 fatty acids in the membranes of the cells increases the physicochemical stability and functional integrity. It also makes the cells less susceptible to oxidative damage and also decreases the formation of lipid peroxidases. They protect from cardiovascular disorders and may also reduce the risks and symptoms for other disorders including diabetes, dementia, rheumatoid arthritis, asthma, stroke, inflammatory bowel disease, ulcerative colitis, mental decline, and some cancers. They aid in proper functioning of central nervous system.
Hypolipidaemic action: It produces a reduction in plasma triglycerides by reducing bad cholesterol or very low density lipoproteins.
Antiinflammatory action: Omega - 3 fatty acids are long chain poly unsaturated fatty acids.They compete with arachidonic acid for cyclo-oxygenase and lipoxygenase They inhibits inflammatory mediators by inhibiting leukotriene synthesis pathway.
Antithrombotic effect: They promote vasodilatation, a reduction in platelet aggregation, increased bleeding time and decreased platelet counts
Pharmacokinets of Docosahexenoic AcidN/AOnset of Action for Docosahexenoic AcidN/ADuration of Action for Docosahexenoic AcidN/AHalf Life of Docosahexenoic AcidN/ASide Effects of Docosahexenoic Acid1.Loose stools
2.Abdominal discomfort
3.Belching
4.Prolong bleeding time slightly
5.Nausea
6.Vomiting
7.Diarrhoea
8.Constipation
Contra-indications of Docosahexenoic AcidHypersensitivity to the drugSpecial Precautions while taking Docosahexenoic Acid1.Haemorrhagic disorders
2.Patient on anticoagulants therapy
3.Hepatic impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
Infants: ContraindicatedIndications for Docosahexenoic Acid1.Coronary artery disease
2.Hypertension
3.Atherosclerosis related disorders
4.Obesity
5.Fatty diet
6.Hyperlipidaemia
7.Smoking
8.Diabetes
Interactions for Docosahexenoic AcidN/ATypical Dosage for Docosahexenoic Acid120 - 240 mg / day in single or 2 divided dose with Eicosapentaenoic acid.Schedule of Docosahexenoic AcidN/AStorage Requirements for Docosahexenoic AcidStore in airtight containers. Protect from light.
Effects of Missed Dosage of Docosahexenoic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Docosahexenoic AcidGive supportive measures and symptomatic treatment.Vitamin C
About Vitamin CWater soluble vitamin, antioxidant.Mechanism of Action of Vitamin CVitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.Pharmacokinets of Vitamin CAbsorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin CN/ADuration of Action for Vitamin CN/AHalf Life of Vitamin CN/ASide Effects of Vitamin C1. Discomfort at injection site
2. Acid urine
3. Renal calculi
4. Oxaluria
Contra-indications of Vitamin CNo known contraindicationsSpecial Precautions while taking Vitamin C1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Vitamin C1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries
Interactions for Vitamin COral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.Typical Dosage for Vitamin COral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Scurvy:
Oral:
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.
Schedule of Vitamin CC1 (Oral)
C (Parenteral)Storage Requirements for Vitamin CStore in a cool dry area in a well closed container. Protects from moisture, light and direct heat.Effects of Missed Dosage of Vitamin CTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin CDiscontinue the therapy and provide symptomatic and supportive measures.Vitamin E
About Vitamin EN/AMechanism of Action of Vitamin EVitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.Pharmacokinets of Vitamin EAbsorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.
Onset of Action for Vitamin EN/ADuration of Action for Vitamin EN/AHalf Life of Vitamin EN/ASide Effects of Vitamin E1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence
Contra-indications of Vitamin E1. Hypersensitivity to the drug
2. Should not administer intravenously
Special Precautions while taking Vitamin E1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens
Pregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Vitamin E1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant
Interactions for Vitamin EOral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.
Typical Dosage for Vitamin EOral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.
Schedule of Vitamin EC1Storage Requirements for Vitamin EStore in a well closed container in a cool dry place. Protect from light.Effects of Missed Dosage of Vitamin ETake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin EProvide supportive measures and symptomatic treatment.Manganese
About ManganeseMagnesium is essential for enzyme activity, calcium and potassium uptake, nerve transmission, bone formation and metabolism of carbohydrates and minerals. It is magnesium, not calcium, which helps form hard tooth enamel, resistant to decay. Like calcium and chloride, magnesium also plays a role in regulating the acid-alkaline balance in the body. High magnesium levels in drinking water have been linked to resistance to heart disease. Although it is found in many foods, including dairy products, nuts, vegetables, fish, meat and seafood, deficiencies are common in America due to soil depletion, poor absorption and lack of minerals in drinking water. A diet high in carbohydrates, oxalic acid in foods like raw spinach and phytic acid found in whole grains can cause deficiencies. An excellent source of usable magnesium is beef, chicken or fish broth. High amounts of zinc and vitamin D increase magnesium requirements. Magnesium deficiency can result in coronary heart disease, chronic weight loss, obesity, fatigue, epilepsy and impaired brain function. Chocolate cravings are a sign of magnesium deficiency.Mechanism of Action of ManganeseN/APharmacokinets of ManganeseN/AOnset of Action for ManganeseN/ADuration of Action for ManganeseN/AHalf Life of ManganeseN/ASide Effects of ManganeseN/AContra-indications of ManganeseN/ASpecial Precautions while taking ManganeseN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for ManganeseN/AInteractions for ManganeseN/ATypical Dosage for ManganeseN/ASchedule of ManganeseN/AStorage Requirements for ManganeseN/AEffects of Missed Dosage of ManganeseN/AEffects of Overdose of ManganeseN/AZinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresCopper
About CopperThird most abundant essential trace mineral, A cofactor for many proteins, iron utilization enhancer, Copper deficiency.Mechanism of Action of CopperCopper is one of a relatively small group of metallic elements which are essential to human health. These elements, along with amino and fatty acids as well as vitamins, are required for normal metabolic processes.Pharmacokinets of CopperAbsorption:It is orally well absorbed.Onset of Action for CopperN/ADuration of Action for CopperN/AHalf Life of CopperN/ASide Effects of Copper1.Breathing problems
2.Chest pain
3.Skin hives
4.Rash
5.Swollen skin
6.Upset stomach
Contra-indications of CopperHypersensitivity to the drug
Special Precautions while taking Copper1.Blood pressure
2.Heart or blood vessel disease
Pregnancy Related Informationuse with cautionOld Age Related InformationN/ABreast Feeding Related Informationuse with cautionChildren Related InformationN/AIndications for Copper1. As a supplement for the prevention of cardiovascular disease, anemia, to enhance immunity, and to treat arthritis.Interactions for CopperN/ATypical Dosage for CopperAs directed by the physicianSchedule of CopperN/AStorage Requirements for CopperStore at 15 - 30 degree C. Protect from heat and light. Kept the container tightly closed after use. Keep out of the reach of childrenEffects of Missed Dosage of CopperTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CopperGive supportive measures and symptomatic treatment.Selenium
About SeleniumA vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.Mechanism of Action of SeleniumN/APharmacokinets of SeleniumN/AOnset of Action for SeleniumN/ADuration of Action for SeleniumN/AHalf Life of SeleniumN/ASide Effects of SeleniumN/AContra-indications of SeleniumN/ASpecial Precautions while taking SeleniumN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for SeleniumN/AInteractions for SeleniumN/ATypical Dosage for SeleniumN/ASchedule of SeleniumN/AStorage Requirements for SeleniumN/AEffects of Missed Dosage of SeleniumN/AEffects of Overdose of SeleniumN/ALycopene
About LycopeneCarotenoid;Terpenes and terpenoids, Dietary antioxidant.Mechanism of Action of LycopeneN/APharmacokinets of LycopeneN/AOnset of Action for LycopeneN/ADuration of Action for LycopeneN/AHalf Life of LycopeneN/ASide Effects of LycopeneN/AContra-indications of LycopeneN/ASpecial Precautions while taking LycopeneN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for LycopeneN/AInteractions for LycopeneN/ATypical Dosage for LycopeneN/ASchedule of LycopeneN/AStorage Requirements for LycopeneN/AEffects of Missed Dosage of LycopeneN/AEffects of Overdose of LycopeneN/ACarotenoids
About CarotenoidsAntioxidants,vitamin A supplements.Mechanism of Action of CarotenoidsThe primary benefit of carotenoids lies in their antioxidant potential. Antioxidants are compounds that protect your body?s cells from damage by unstable oxygen molecules called free radicals. Carotenoids guard against certain types of cancer, apparently by limiting the abnormal growth of cells. For instance, lycopene appears to inhibit prostate cancer formation. In addition, carotenoids fight heart disease by blocking the formation of LDL (?bad? cholesterol) which leads to heart attacks. The carotenoids lutein and zeaxanthin both reduce the risk of macular degeneration. Pharmacokinets of CarotenoidsN/AOnset of Action for CarotenoidsN/ADuration of Action for CarotenoidsN/AHalf Life of CarotenoidsN/ASide Effects of CarotenoidsN/AContra-indications of CarotenoidsN/ASpecial Precautions while taking CarotenoidsN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for CarotenoidsN/AInteractions for CarotenoidsN/ATypical Dosage for CarotenoidsN/ASchedule of CarotenoidsN/AStorage Requirements for CarotenoidsN/AEffects of Missed Dosage of CarotenoidsN/AEffects of Overdose of CarotenoidsN/AHome Delivery for Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + Carotenoids in Your City
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Docosahexenoic acid + Vitamin C +Vitamin E + Manganese + Zinc + Copper + Selenium + Lycopene + Carotenoids is a generic medicine name and there are several brands available for it. Some of the brands for docosahexenoic acid + vitamin c +vitamin e + manganese + zinc + copper + selenium + lycopene + carotenoids might be better known than docosahexenoic acid + vitamin c +vitamin e + manganese + zinc + copper + selenium + lycopene + carotenoids itself. If the pharmacy that's willing to deliver medicines to your home doesn't have docosahexenoic acid + vitamin c +vitamin e + manganese + zinc + copper + selenium + lycopene + carotenoids in stock, you can ask for one of the branded alternatives for docosahexenoic acid + vitamin c +vitamin e + manganese + zinc + copper + selenium + lycopene + carotenoids.