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- Pharmacology For Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + Menthol
Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + Menthol Pharmacology
Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + Menthol
About Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AMechanism of Action of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/APharmacokinets of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AOnset of Action for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/ADuration of Action for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AHalf Life of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/ASide Effects of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AContra-indications of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/ASpecial Precautions while taking Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicatedChildren Related InformationN/AIndications for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholCough and coldInteractions for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/ATypical Dosage for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/ASchedule of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AStorage Requirements for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AEffects of Missed Dosage of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AEffects of Overdose of Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + MentholN/AAmbroxol
About AmbroxolActive N-desmethyl metabolite of bromhexine,systemically active mucolytic agent, Secretomotoric and expectoration improver.Mechanism of Action of AmbroxolAmbroxol hydrochloride acts as an expectoration improver and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and by breaking network of fibres in tenacious sputum . It induces thin copious bronchial secretion and possesses antioxidant properties.Pharmacokinets of AmbroxolN/AOnset of Action for AmbroxolN/ADuration of Action for AmbroxolN/AHalf Life of AmbroxolN/ASide Effects of Ambroxol1. Rhinorrhoea
2. Lacrimations
3. Allergic reactions
4. Gastric irritation.Contra-indications of AmbroxolHypersensitivity to the Ambroxol hydrochloride or Bromhexine.Special Precautions while taking Ambroxol1.Hepatic impairment
2.Renal impairment
3.Gastric and duodenal ulcer
4.Convulsive disorders
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Ambroxol1. As Expectorant and mucolytic
2. Conditions associated with production of viscid mucous
3. Bronchitis
4. Pharyngitis
5. Laryngitis
6. Rhinitis
7. Sinusitis
8. Asthmatic bronchitis
9. Mucous bronchiectasis
10. Chronic Pneumonia.Interactions for AmbroxolN/ATypical Dosage for AmbroxolOral: 15mg to 30mg three times daily.
Children (6 to 12years): 5ml 2 to 3 times daily
Children (2 to 6years): 2.5ml thrice daily. (5ml liquid contains 30mg Ambroxol hydrochloride)
Children up to 2 years: 7.5mg two times daily
Schedule of AmbroxolHStorage Requirements for AmbroxolStore in a cool dry place and protect from light. Keep out of reach of children.Effects of Missed Dosage of AmbroxolTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of AmbroxolProvide symptomatic treatment and supportive measures.Guaiphenesin
About GuaiphenesinPropanediol derivative, Expectorant.Mechanism of Action of GuaiphenesinGuaiphenesin is an expectorant which after absorption from the gastrointestinal tract secreted by tracheobronchial glands and directly increase bronchial secretion and mucosal ciliary action. It increases respiratory tract fluid by reducing adhesiveness and surface tension, reducing viscosity of the secretions and there by facilitating their removal and clears chest congestion.
Action in local vaginal preparations: Guaiphenesin helps to thin the thick or sticky cervical mucus.
Pharmacokinets of GuaiphenesinAbsorption: Well absorbed orally.Distribution: It is secreted by the tracheobronchial glands.
Metabolism: It is metabolized primarily to Beta-2-methoxyphenoxy-lactic acid. Excretion: It is excreted in the urine.
Onset of Action for GuaiphenesinN/ADuration of Action for GuaiphenesinN/AHalf Life of Guaiphenesin60 minutesSide Effects of Guaiphenesin1. Headache
2. Dizziness
3. Nausea
4. Vomiting
5. Rash
6. Diarrhoea
7. Drowsiness
8. Stomach pain
Contra-indications of Guaiphenesin1. Hypersensitivity to the drug
2. Chronic or persistent cough associated with chronic lower respiratory tract diseases
3. Asthma
4. Bronchitis
5. Chronic obstructive pulmonary disease (COPD)
6. Emphysema
Special Precautions while taking Guaiphenesin1. Porphyria
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationMay be usedIndications for Guaiphenesin1. Expectorant
2. Thick or sticky cervical mucus
Interactions for GuaiphenesinN/ATypical Dosage for GuaiphenesinOral :
Adults and children over 12 years: 100 to 400mg up to 6 times daily as required.Maximum dose: 2.4g/day
Children (age 6 to 11): 100 to 200mg up to 6 times daily as required.Maximum dose: 1.2g/day
Children (age 2 to 5): 50 to 100mg up to 6 times daily as required.Maximum dose: 600mg/day
Extended release:
Adults and children over 12 years: 600 to 1200mg twice daily. Not to exceed 2.4g in 24 hours
Children (age 6 to 12): 600mg twice daily. Not to exceed 1.2g in 24 hours
Children (age 2 to 6): 300mg twice daily. Not to exceed 600mg in 24 hours
Thick or sticky cervical mucus: 200mg 2 to 3 times daily from 4 days prior to ovulation and continue through ovulation day.
Schedule of GuaiphenesinN/AStorage Requirements for GuaiphenesinStore at a temperature below 30 degree C. Keep out of reach of children.Effects of Missed Dosage of GuaiphenesinTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of GuaiphenesinProvide symptomatic treatment and supportive measures.Ammonium chloride
About Ammonium chlorideAmmonium compound, Acidifier,Expectorant.Mechanism of Action of Ammonium chlorideN/APharmacokinets of Ammonium chlorideN/AOnset of Action for Ammonium chlorideN/ADuration of Action for Ammonium chlorideN/AHalf Life of Ammonium chlorideN/ASide Effects of Ammonium chlorideN/AContra-indications of Ammonium chlorideN/ASpecial Precautions while taking Ammonium chlorideN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Ammonium chlorideN/AInteractions for Ammonium chlorideN/ATypical Dosage for Ammonium chlorideN/ASchedule of Ammonium chlorideN/AStorage Requirements for Ammonium chlorideN/AEffects of Missed Dosage of Ammonium chlorideN/AEffects of Overdose of Ammonium chlorideN/APseudoephedrine
About PseudoephedrineAlpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.Mechanism of Action of PseudoephedrineIt is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasal stuffiness.Pharmacokinets of PseudoephedrineAbsorption: Well absorbed orally, Distribution: Widely distributed throughout the body, Metabolism: Partially metabolized in liver by N-demethylation, Excretion: Excreted through urine mainly as unchanged drug and also as metabolites.Onset of Action for Pseudoephedrine30 minutesDuration of Action for Pseudoephedrine4 to 8 hoursHalf Life of PseudoephedrineN/ASide Effects of Pseudoephedrine1. Rise in blood pressure
2. Tachycardia
3. Arrhythmias
4. CNS stimulation
5. Restlessness
6. Insomnia
7. Anxiety
8. Tremors
9. Skin rashes
10. Urinary retention
11. Respiratory difficulties
Contra-indications of Pseudoephedrine1. Hypersensitivity to the drug
2. Severe hypertension
3. Coronary artery disease
4. Patients taking monoamine oxidase inhibitors (MAOIs) or who have taken MAOIs within the previous 14 days
5. Extended release preparations are contraindicated in children below 12 yearsSpecial Precautions while taking Pseudoephedrine1. Hypertension
2. Cardiac diseases
3. Diabetes
4. Glaucoma
5. Prostatic hyperplasia
6. Hyperthyroidism
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Pseudoephedrine1. Nasal and Eustachian tube congestion
2.Upper respiratory tract congestion
3.Adjunctive therapy in symptomatic relief of common cold, allergic rhinitis, blocked Eustachian tube, and upper respiratory tract infectionsInteractions for PseudoephedrineN/ATypical Dosage for PseudoephedrineOral:
Adults and children over 12 years: 60mg 3 to 4 times daily
Maximum dose: 240mg/day
Children (age 6 to 12): 30mg 3 to 4 times daily
Maximum dose: 120mg/day
Children (age 2 to 6): 15mg 3 to 4 times daily
Maximum dose: 60mg/day or 4mg/kg.
Schedule of PseudoephedrineN/AStorage Requirements for PseudoephedrineStore at controlled room temperature at a range of 15 to 30 degree C. Keep out of reach of childrenEffects of Missed Dosage of PseudoephedrineTake the missed dose as soon as noticed and if it is the time for next dose
Effects of Overdose of PseudoephedrineContinue the regular schedule. Do not double the dose.
Over dosage and poisoning: Provide symptomatic treatment and supportive measures. Perform emesis and gastric lavage within 4 hours of ingestion. If renal function is adequate forced diuresis will increase elimination of the drug. (Do not force diuresis in severe poisoning). Monitor and assist vital signs, cardiac state and electrolyte balance. Treat cardiac toxicity with Propranolol or other effective drugs. Treat seizures with Diazepam (I.V.) and give dilute Potassium chloride solution for hypokalaemia.
Chlorpheniramine Maleate
About Chlorpheniramine MaleateN/AMechanism of Action of Chlorpheniramine MaleateN/APharmacokinets of Chlorpheniramine MaleateN/AOnset of Action for Chlorpheniramine MaleateN/ADuration of Action for Chlorpheniramine MaleateN/AHalf Life of Chlorpheniramine MaleateN/ASide Effects of Chlorpheniramine MaleateN/AContra-indications of Chlorpheniramine MaleateFirst Generation alkylamine H1 Antagonist, Antihistamine.Special Precautions while taking Chlorpheniramine MaleateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Chlorpheniramine MaleateN/AInteractions for Chlorpheniramine MaleateN/ATypical Dosage for Chlorpheniramine MaleateN/ASchedule of Chlorpheniramine MaleateN/AStorage Requirements for Chlorpheniramine MaleateN/AEffects of Missed Dosage of Chlorpheniramine MaleateN/AEffects of Overdose of Chlorpheniramine MaleateN/AMenthol
About MentholTerpenes and terpenoid, Antipruritic, decongestant, topical analgesic.Mechanism of Action of MentholMenthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and mild local anaesthetic effect relieves itching. It has good soothing effect and acts as a demulcent. It also acts as a carminative.Pharmacokinets of MentholN/AOnset of Action for MentholN/ADuration of Action for MentholN/AHalf Life of MentholN/ASide Effects of Menthol1.Irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
12.Contact dermatitis
13.Allergic reactions
Contra-indications of Menthol1. Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Menthol1.Should not apply Menthol directly in to or near the nostrils of small children or asthma patients
2.Prolonged use
3.Seizures
4.Should not take steam inhalation orally
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with caution
Children Related InformationUse with caution
below 2 years: ContraindicatedIndications for Menthol1. Rubefacient.
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5.Sore throat
6.Cold sores
7.Hay fever
8.As an inhalant to relieve nasal, bronchial, or upper respiratory congestion
9.Sinusitis
10.Bronchial cough
11.Pharyngeal inflammation
Interactions for MentholN/ATypical Dosage for MentholDosage individualized based on requirements of the patient.
Lozenges: Dissolve lozenge (5%-10% menthol) slowly in the mouth hourly as needed by the patients.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Menthol (3.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1tsp of solution for each pint, up to thrice daily
Schedule of MentholN/AStorage Requirements for MentholStore at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.Effects of Missed Dosage of MentholTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MentholProvide symptomatic treatment and supportive measures.Home Delivery for Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + Menthol in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol and other medicines and health products. Home delivery services for ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol before they complete the sale. You can get this information while placing the order for ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol with the pharmacy.
Ambroxol + Guaiphenesin + Ammonium Chloride + Pseudoephedrine + Chlorpheniramine Maleate + Menthol is a generic medicine name and there are several brands available for it. Some of the brands for ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol might be better known than ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol in stock, you can ask for one of the branded alternatives for ambroxol + guaiphenesin + ammonium chloride + pseudoephedrine + chlorpheniramine maleate + menthol.