Nepafenac Pharmacology

Nepafenac

About Nepafenac
NSAID,anti inflammatory eye preparation
Mechanism of Action of Nepafenac
Nepafenac is a prodrug. After penetrating the cornea, nepafenac undergoes rapid bioactivation to amfenac, which is a potent NSAID that uniformly inhibits the COX1 and COX2 activity.
Pharmacokinets of Nepafenac
Absorption:Nepafenac rapidly cross the cornea (6 times faster than diclofenac in vitro)
Onset of Action for Nepafenac
N/A
Duration of Action for Nepafenac
N/A
Half Life of Nepafenac
N/A
Side Effects of Nepafenac
1.Foreign body sensation in the eye
2.Decreased visual activity
3.Eye redness
4.Itching or watering of the eye
5.Increased sensitivity to light
6.Headache
7.Nausea
8.Vomiting
9.Stuffy nose
Contra-indications of Nepafenac
1.Hypersensitivity
2.Diabetes mellitus
3.Dry eye syndrome
4.Rheumatoid arthritis
5.Bleeding disorders
Special Precautions while taking Nepafenac
1.Sensitivity to aspirin or phenylacetic acid deivatives
2.May cause increased bleeding in ocular tissues
3.May cause keratitis & corneal damage (risk increases if applied earlier than 1 day presurgery or longer than 2 wk postsurgery)
Pregnancy Related Information
Contraindicated
Old Age Related Information
N/A
Breast Feeding Related Information
Use with caution
Children Related Information
Not recommended below 10 yrs
Indications for Nepafenac
Treatment of pain and inflammation associated with cataract surgery.
Interactions for Nepafenac
N/A
Typical Dosage for Nepafenac
Nepafenac is usually given as 1 drop in the affected eye 3 times per day, starting 1 day before cataract surgery.
Do not use nepafenac ophthalmic for longer than 14 days after your surgery unless the doctor tells you to. Wash the hands before using the eye drops.
Schedule of Nepafenac
N/A
Storage Requirements for Nepafenac
N/A
Effects of Missed Dosage of Nepafenac
Use the missed dose as soon as remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.
Effects of Overdose of Nepafenac
An overdose of nepafenac ophthalmic is not likely to cause life-threatening symptoms.

Home Delivery for Nepafenac in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including nepafenac.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for nepafenac and other medicines and health products. Home delivery services for nepafenac may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take nepafenac only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for nepafenac before they complete the sale. You can get this information while placing the order for nepafenac with the pharmacy.

Nepafenac is a generic medicine name and there are several brands available for it. Some of the brands for nepafenac might be better known than nepafenac itself. If the pharmacy that's willing to deliver medicines to your home doesn't have nepafenac in stock, you can ask for one of the branded alternatives for nepafenac.