Lactic Acid + Urea + Vitamin E + Propylene Glycol Pharmacology

Lactic Acid + Urea + Vitamin E + Propylene Glycol

About Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Mechanism of Action of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Pharmacokinets of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Onset of Action for Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Duration of Action for Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Half Life of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Side Effects of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Contra-indications of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Special Precautions while taking Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
May be used
Children Related Information
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Indications for Lactic Acid + Urea + Vitamin E + Propylene Glycol
Dry and irritated skin conditions.
Interactions for Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Typical Dosage for Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Schedule of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Storage Requirements for Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Effects of Missed Dosage of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Effects of Overdose of Lactic Acid + Urea + Vitamin E + Propylene Glycol
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Lactic acid

About Lactic acid
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Mechanism of Action of Lactic acid
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Pharmacokinets of Lactic acid
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Onset of Action for Lactic acid
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Duration of Action for Lactic acid
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Half Life of Lactic acid
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Side Effects of Lactic acid
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Contra-indications of Lactic acid
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Special Precautions while taking Lactic acid
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Lactic acid
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Interactions for Lactic acid
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Typical Dosage for Lactic acid
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Schedule of Lactic acid
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Storage Requirements for Lactic acid
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Effects of Missed Dosage of Lactic acid
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Effects of Overdose of Lactic acid
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Urea

About Urea
Diamide salt of carbonic acid, Topical dermatological product ,Moisturiser.
Mechanism of Action of Urea
Urea is used in skin preparations as hydrating agent.It is used in scaling conditions and may be ueful in elderly patients.It is occassionally used with corticosteroids to enhance penetration of corticosteroids.
Pharmacokinets of Urea
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Onset of Action for Urea
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Duration of Action for Urea
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Half Life of Urea
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Side Effects of Urea
1.Skin rash
2.Stinging
3.Irritation
Contra-indications of Urea
1.Hypersensitivity to the drug
Special Precautions while taking Urea
Broken, inflamed, or burnt skin
Infection
Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Urea
1.As moisturiser
Interactions for Urea
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Typical Dosage for Urea
Apply a thin film to the affected area.
Schedule of Urea
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Storage Requirements for Urea
Store at room temperature between 15 and 30 degrees C .Keep in a well closed container. Keep out of the reach of children.
Effects of Missed Dosage of Urea
Apply the missed dose as soon as noticed. If it is almost time for the next dose, skip the missed dose and continue the regular schedule.
Effects of Overdose of Urea
Give supportive measures and symptomatic treatment.

Vitamin E

About Vitamin E
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Mechanism of Action of Vitamin E
Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.
Pharmacokinets of Vitamin E
Absorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.
Onset of Action for Vitamin E
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Duration of Action for Vitamin E
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Half Life of Vitamin E
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Side Effects of Vitamin E
1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence


Contra-indications of Vitamin E
1. Hypersensitivity to the drug
2. Should not administer intravenously
Special Precautions while taking Vitamin E
1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens
Pregnancy Related Information
May be used
Old Age Related Information
N/A
Breast Feeding Related Information
May be used
Children Related Information
N/A
Indications for Vitamin E
1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant


Interactions for Vitamin E
Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.

Typical Dosage for Vitamin E
Oral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.



Schedule of Vitamin E
C1
Storage Requirements for Vitamin E
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Vitamin E
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vitamin E
Provide supportive measures and symptomatic treatment.

Propylene glycol

About Propylene glycol
Skin softening agent, Emolient(humectant).
Mechanism of Action of Propylene glycol
Propylene glycol is used as moisturizer, which makes the external layers of the skin softer by its hydration.Propylene glycol has humectant properties and is used in topical moisturising preparations.
Pharmacokinets of Propylene glycol
Pharmaco Kinetic
Absorption: Propylene glycol is absorbed through damaged skin.
Onset of Action for Propylene glycol
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Duration of Action for Propylene glycol
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Half Life of Propylene glycol
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Side Effects of Propylene glycol
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Contra-indications of Propylene glycol
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Special Precautions while taking Propylene glycol
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Propylene glycol
1.As emollient
Interactions for Propylene glycol
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Typical Dosage for Propylene glycol
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Schedule of Propylene glycol
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Storage Requirements for Propylene glycol
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Effects of Missed Dosage of Propylene glycol
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Effects of Overdose of Propylene glycol
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