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- Pharmacology For Eberconazole + Mometasone
Eberconazole + Mometasone Pharmacology
Eberconazole + Mometasone
About Eberconazole + MometasoneN/AMechanism of Action of Eberconazole + MometasoneN/APharmacokinets of Eberconazole + MometasoneN/AOnset of Action for Eberconazole + MometasoneN/ADuration of Action for Eberconazole + MometasoneN/AHalf Life of Eberconazole + MometasoneN/ASide Effects of Eberconazole + MometasoneN/AContra-indications of Eberconazole + MometasoneN/ASpecial Precautions while taking Eberconazole + MometasoneN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicatedChildren Related InformationN/AIndications for Eberconazole + MometasoneTreatment of mild to moderate inflammed cutaneous mycoses.Interactions for Eberconazole + MometasoneN/ATypical Dosage for Eberconazole + MometasoneN/ASchedule of Eberconazole + MometasoneN/AStorage Requirements for Eberconazole + MometasoneN/AEffects of Missed Dosage of Eberconazole + MometasoneN/AEffects of Overdose of Eberconazole + MometasoneN/AEberconazole
About EberconazoleTopical imidazole derivative, Antifungal.Mechanism of Action of EberconazoleEberconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the Ergosterol synthesis which is an essential component of the cytoplasmic membrane. This leads to an alteration in its structure and function, thereby inhibiting the growth of the fungus.Pharmacokinets of EberconazoleN/AOnset of Action for EberconazoleN/ADuration of Action for EberconazoleN/AHalf Life of EberconazoleN/ASide Effects of EberconazoleItchingContra-indications of EberconazoleHypersensitivity to EberconazoleSpecial Precautions while taking EberconazoleN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Eberconazole1.Dermatophytoses
2.Candidiasis
3.Pityriasis
Interactions for EberconazoleN/ATypical Dosage for EberconazoleTopical application: Apply the cream to the affected area twice dailySchedule of EberconazoleN/AStorage Requirements for EberconazoleStore at room temperature.Protect from heat,light and moisture.Keep out of the reach of childrenEffects of Missed Dosage of EberconazoleTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.Effects of Overdose of EberconazoleGive supportive measures and symptomatic treatment.Mometasone
About MometasoneA glucocorticoid steroid, Anti psoriatic,anti asthma ,anti inflammatory.Mechanism of Action of MometasoneMometasone is a topical medium potency glucocorticoid. The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-a, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of MometasoneAbsorption: Mometasone is absorbed through intact skin after topical administration and the amount absorbed is depending on the type of inflammation, vehicle used, area of skin and the epidermal barrier. Absorption is increased in inflammation, occlusion and skin damage.Onset of Action for MometasoneN/ADuration of Action for MometasoneN/AHalf Life of MometasoneN/ASide Effects of Mometasone1.Thinning of epidermis
2.Burning
3.Itching
4.Irritation
5.Atrophy (Dermal changes)
6.Telangiectasia
7.Striae
8.Hypopigmentation
9.Contact dermatitis
10.Perioral dermatitis
11.Cataract, Glaucoma, Corneal ulcers caused by application around eyelids and surrounding skin
12.Dry skin
13.Stinging
14.TinglingContra-indications of Mometasone1.Hypersensitivity to Mometasone and other corticosteroids
2.Acne vulgaris
3.Acne Rosacea
5.Tuberculosis infection of the skin
6.Viral, fungal or bacterial primary infections
7.UlcersSpecial Precautions while taking Mometasone1.Avoid the use of medicament if irritation or hypersensitivity occurs
2.Prolonged use
3.Psoriasis
4.Avoid contact with eyes
5.Avoid occlusive dressing
6.Not used more than 5 days on the face or in the children
7.Withdraw gradually after prolonged use
8.Use caution on areas where the skin creases, such as armpits, knees, and elbows
9.Avoid application on large surface areaPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: contraindicated
Indications for Mometasone1.Otitis externa
2 Eczema
3.Dermatoses (secondary infected)
4.Psoriasis
5.Neuro dermatitis
6.Intertrigo
7.Lichen planus
8.Anal and vulval pruritisInteractions for MometasoneN/ATypical Dosage for MometasoneTopical: Mometasone Furoate 0.1 % cream, ointment or lotion is used.
Clean the affected area and wash with warm water and then dry. Apply 2 - 3 times daily for 2 weeks with gentle massage.
Schedule of MometasoneHStorage Requirements for MometasoneStore at room temperature. Protect from heat and light. Keep the container tightly closed. Keep out of the reach of childrenEffects of Missed Dosage of MometasoneApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MometasoneGive supportive measures and symptomatic treatment.
Home Delivery for Eberconazole + Mometasone in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for eberconazole + mometasone and other medicines and health products. Home delivery services for eberconazole + mometasone may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take eberconazole + mometasone only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for eberconazole + mometasone before they complete the sale. You can get this information while placing the order for eberconazole + mometasone with the pharmacy.
Eberconazole + Mometasone is a generic medicine name and there are several brands available for it. Some of the brands for eberconazole + mometasone might be better known than eberconazole + mometasone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have eberconazole + mometasone in stock, you can ask for one of the branded alternatives for eberconazole + mometasone.