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- Pharmacology For Cefadroxil + Lactobacillus
Cefadroxil + Lactobacillus Pharmacology
Cefadroxil + Lactobacillus
About Cefadroxil + LactobacillusN/AMechanism of Action of Cefadroxil + LactobacillusN/APharmacokinets of Cefadroxil + LactobacillusN/AOnset of Action for Cefadroxil + LactobacillusN/ADuration of Action for Cefadroxil + LactobacillusN/AHalf Life of Cefadroxil + LactobacillusN/ASide Effects of Cefadroxil + LactobacillusN/AContra-indications of Cefadroxil + LactobacillusN/ASpecial Precautions while taking Cefadroxil + LactobacillusN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Cefadroxil + LactobacillusN/AInteractions for Cefadroxil + LactobacillusN/ATypical Dosage for Cefadroxil + LactobacillusN/ASchedule of Cefadroxil + LactobacillusN/AStorage Requirements for Cefadroxil + LactobacillusN/AEffects of Missed Dosage of Cefadroxil + LactobacillusN/AEffects of Overdose of Cefadroxil + LactobacillusN/ACefadroxil
About CefadroxilFirst Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibioticMechanism of Action of CefadroxilCefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil
Pharmacokinets of CefadroxilAbsorption: well absorbed orally, Distribution: widely distributed, Metabolism: not metabolized, Excretion: excreted mainly through urine; & small amount is excreted in breast milk.Onset of Action for CefadroxilWithin one hourDuration of Action for CefadroxilUp to16 hoursHalf Life of CefadroxilN/ASide Effects of Cefadroxil1.Nausea
2.Vomiting
3.Diarrhea
4.Gastritis
5.Super infection
6.Candidiasis
7.Rash
8.Hypersensitivity reactions
9.Angioedema
10.Vaginitis
11.Neutropenia
12.Thrombocytopenia
13.Headache
14.Dizziness
15.Hallucinations
16.Nephritis
17.Elevated liver enzymes.Contra-indications of Cefadroxil1.Hypersensitivity to cephalosporins
2.Porphyria
3.Neuromuscular disorders.
Special Precautions while taking Cefadroxil1.Renal impairment
2.Patient allergic to penicillins
3.Neuromuscular disorders
Pregnancy Related InformationUse with caution.Old Age Related InformationMay be used.Breast Feeding Related InformationUse with caution.Children Related InformationMay be used.Indications for Cefadroxil1. Urinay tract infections
2. Tonsillitis & Pharyngitis
3. Skin &soft tissue infections
4. Otitis media.
Interactions for CefadroxilAminoglycosides (Gentamycin, Tobramycin): Nephrotoxicity of aminoglycosides potentiated.
Oral anticoagulants: Hypoprothrombinaemic effect potentiated, bleeding complications may occur.
Bacteriostatic Agents like Chloramphenicol: Decrease efficacy of Cefadroxil.
Probenecid: Slows tubular excretion and this enhances efficacy.
Frusemide & Ethacrynic Acid: Potentiate Nephrotoxicity of Cefadroxil.
Urine Glucose: False positive with Benedicts solution and Fehlings solution.
Direct Coomb?s Test: False positive.
Urinary 17-Ketosteroid values: Falsely elevated values.
Typical Dosage for CefadroxilAdults:500mg to 1gm 12 hourly
Children:30mg/kg/day two times daily
Schedule of CefadroxilHStorage Requirements for CefadroxilStore in a cool place.
Effects of Missed Dosage of CefadroxilTake the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.Effects of Overdose of CefadroxilSymptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measuresLactobacillus
About LactobacillusLactic acid bacteria, Probiotic,Antidiarrhoeal.Mechanism of Action of LactobacillusLactobacillus is a probiotic and it is called as friendly bacteria. It is used along with antibiotic in order to restore the body`s natural microbial flora with in the digestive tract. Lactobacillus helps in the breakdown of food and leads to the production of lactic acid, hydrogen peroxide and other byproducts. This will alter the intestinal pH and that make the environment hostile for pathogens.Pharmacokinets of LactobacillusAbsorption: It is orally well absorbed after oral administration.
Onset of Action for LactobacillusN/ADuration of Action for LactobacillusN/AHalf Life of LactobacillusN/ASide Effects of Lactobacillus1.Abdominal discomfort
2.Vaginal irritation (when used vaginally)
Contra-indications of Lactobacillus1.Recent bowel surgery
2.Intestinal damage
3.Weakened immune system
Special Precautions while taking LactobacillusPatient on Inulin treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Use with cautionIndications for Lactobacillus1.Aphthous stomatitis
2.Hypochlorhydria
3.Hepatic encephalopathy
4.Adjuvant to antibiotic therapy
5.Diarrhoea.Interactions for LactobacillusN/ATypical Dosage for LactobacillusAdult: 60 - 150 million spores 3 times daily depending on the severity of infections.
Vaginal bacterial infections: 1- 2 billion bacteria 2 - 3 times daily
Suppositories:
Vaginal infections, cystitis: 1 - 2 suppositories are inserted in to vagina at night for 2 weeks. Each suppository contains 1 - 2 billion lactobacilli
Schedule of LactobacillusN/AStorage Requirements for LactobacillusRefrigerate below 5 degree C.Effects of Missed Dosage of LactobacillusN/AEffects of Overdose of LactobacillusGive supportive measures and symptomatic treatmentHome Delivery for Cefadroxil + Lactobacillus in Your City
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Cefadroxil + Lactobacillus is a generic medicine name and there are several brands available for it. Some of the brands for cefadroxil + lactobacillus might be better known than cefadroxil + lactobacillus itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefadroxil + lactobacillus in stock, you can ask for one of the branded alternatives for cefadroxil + lactobacillus.