Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin Pharmacology

Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin

About Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Mechanism of Action of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Pharmacokinets of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Onset of Action for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Duration of Action for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Half Life of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Side Effects of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Contra-indications of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Special Precautions while taking Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
Use with caution
Children Related Information
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Indications for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
1.Iron deficiency anemia
2.Pregnancy supplement
Interactions for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Typical Dosage for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Schedule of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Storage Requirements for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Effects of Missed Dosage of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Effects of Overdose of Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin
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Folic Acid

About Folic Acid
Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.
Mechanism of Action of Folic Acid
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Pharmacokinets of Folic Acid
Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic Acid
Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic Acid
Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic Acid
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Side Effects of Folic Acid
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Contra-indications of Folic Acid
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Special Precautions while taking Folic Acid
1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Folic Acid
1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid
1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic Acid
Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic Acid
C1 (Oral)
C (Parenteral)
Storage Requirements for Folic Acid
Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.
Effects of Missed Dosage of Folic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Folic Acid
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Zinc Sulphate

About Zinc Sulphate
Zinc compound, An astringent , Adjunctive treatment of Wilson?s disease.
Mechanism of Action of Zinc Sulphate
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Pharmacokinets of Zinc Sulphate
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Onset of Action for Zinc Sulphate
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Duration of Action for Zinc Sulphate
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Half Life of Zinc Sulphate
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Side Effects of Zinc Sulphate
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Contra-indications of Zinc Sulphate
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Special Precautions while taking Zinc Sulphate
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Zinc Sulphate
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Interactions for Zinc Sulphate
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Typical Dosage for Zinc Sulphate
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Schedule of Zinc Sulphate
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Storage Requirements for Zinc Sulphate
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Effects of Missed Dosage of Zinc Sulphate
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Effects of Overdose of Zinc Sulphate
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Iron (Carbonyl Iron)

About Iron (Carbonyl Iron)
A highly pure, nontoxic Iron(a minimum 98% iron content), Iron dietary supplement and to treat iron deficiency.
Mechanism of Action of Iron (Carbonyl Iron)
Iron formulations exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Pharmacokinets of Iron (Carbonyl Iron)
Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed.
Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin.
Metabolism: Iron liberated by destruction of haemoglobin is reused by the body.
Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.
Onset of Action for Iron (Carbonyl Iron)
4 days
Duration of Action for Iron (Carbonyl Iron)
2 to 4 months
Half Life of Iron (Carbonyl Iron)
N/A
Side Effects of Iron (Carbonyl Iron)
1. Nausea
2. Epigasttric distress
3. Vomiting
4. Constipation
5. Diarrhoea
6. Black stools
7. Temporary staining of teeth with liquid formulations
Contra-indications of Iron (Carbonyl Iron)
1. Haemolytic anaemia unless iron deficiency anaemia is also present
2. Haemochromatosis
3. Haemosiderosis
4. Peptic ulcer
5. Regional enteritis
6. Ulcerative colitis
7. Those receiving repeated blood transfusions
Special Precautions while taking Iron (Carbonyl Iron)
1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
Indications for Iron (Carbonyl Iron)
1. Iron deficiency
2. Iron deficiency during pregnancy and lactation
3. Iron deficiency in infants and children
Interactions for Iron (Carbonyl Iron)
(Oral Iron): Antacids: GI absorption of iron reduced.
Ascorbic acid: GI absorption of iron enhanced.
Chloramphenicol: Serum iron levels may be increased.
Cimetidine: GI absorption may be reduced.
Levodopa: Decreased levodopa serum levels.
Methyldopa: May result in decreased efficacy of methyldopa.
Quinolones: GI absorption of quinolones decreased.
Penicillamine: Marked reduction in GI absorption of penicillamine.
Tetracyclines: Decrease in the absorption of both tetracyclines and iron salts.
Food: Eggs and milk inhibit iron absorption. Administration of calcium and iron supplementation with food reduces ferrous sulfate absorption by one-third. If combined iron and calcium supplementation required then calcium carbonate should be used and the supplementation taken between meals.
Typical Dosage for Iron (Carbonyl Iron)
Oral:
Ferrous fumarate:
Adults: Starts with 50 to 100mg 2 to 3 times daily. Adjust the dosage based on patient`s response.
Children: 4 to 6mg/kg daily in three divided doses.
Ferrous sulphate:
Adults: 100 to 300mg; twice daily. Increases the dosage based on patient`s response if required up to 300mg 4 times daily.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Ferrous gluconate:
300 to 1200mg daily in three to four divided doses.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Schedule of Iron (Carbonyl Iron)
H
Storage Requirements for Iron (Carbonyl Iron)
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Iron (Carbonyl Iron)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron (Carbonyl Iron)
Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

Adenosylcobalamin

About Adenosylcobalamin
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Mechanism of Action of Adenosylcobalamin
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Pharmacokinets of Adenosylcobalamin
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Onset of Action for Adenosylcobalamin
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Duration of Action for Adenosylcobalamin
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Half Life of Adenosylcobalamin
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Side Effects of Adenosylcobalamin
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Contra-indications of Adenosylcobalamin
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Special Precautions while taking Adenosylcobalamin
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Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Adenosylcobalamin
1.Increasing muscle mass and strength.
2.Improving mental concentration.
3.Depression.
4.Anxiety.
5.Panic attacks.
Interactions for Adenosylcobalamin
Cobamamide has its effect reduced by chloramphenicol
Typical Dosage for Adenosylcobalamin
As directed by thephysision
Schedule of Adenosylcobalamin
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Storage Requirements for Adenosylcobalamin
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Effects of Missed Dosage of Adenosylcobalamin
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Effects of Overdose of Adenosylcobalamin
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Home Delivery for Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin in Your City

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Folic Acid + Zinc Sulphate + Iron (Carbonyl Iron) + Adenosylcobalamin is a generic medicine name and there are several brands available for it. Some of the brands for folic acid + zinc sulphate + iron (carbonyl iron) + adenosylcobalamin might be better known than folic acid + zinc sulphate + iron (carbonyl iron) + adenosylcobalamin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have folic acid + zinc sulphate + iron (carbonyl iron) + adenosylcobalamin in stock, you can ask for one of the branded alternatives for folic acid + zinc sulphate + iron (carbonyl iron) + adenosylcobalamin.