Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium Pharmacology

Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

About Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Mechanism of Action of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Pharmacokinets of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Onset of Action for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Duration of Action for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Half Life of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Side Effects of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Contra-indications of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Special Precautions while taking Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

N/A

Indications for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

1.Osteoporosis
2.Hypocalcaemia
3.Osteomalacia
4.Conditions where additional Calcium is required

Interactions for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Typical Dosage for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Schedule of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Storage Requirements for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Effects of Missed Dosage of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Effects of Overdose of Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium

N/A

Calcitriol

About Calcitriol

N/A

Mechanism of Action of Calcitriol

Calcitriol is a 1, 25-dihydroxycholecalciferol or a Vitamin D analogue. It increases the absorption of Calcium from intestine by forming a calcium binding protein. It reverses the signs of rickets and osteomalacia.

Pharmacokinets of Calcitriol

Absorption: It is readily absorbed after oral administration. Distribution: It is widely distributed in protein bound form. Metabolism: It undergoes metabolism in the liver and kidney. Excretion: It is excreted mainly in the faeces.

Onset of Action for Calcitriol

2 - 6 hours

Duration of Action for Calcitriol

3 - 5 days

Half Life of Calcitriol

3 - 8 hours

Side Effects of Calcitriol

1. Nausea
2. Vomiting
3. Constipation
4. Headache
5. Somnolence
6. Weakness
7. Hypertension
8. Bone and muscle pain
9. Pruritus
10. Weight loss
11. Polyuria
12. Metallic taste
13. Anorexia
14. Dry mouth

Contra-indications of Calcitriol

1. Hypercalcaemia
2. Metastatic calcification
3. Plasma phosphorus level greater than 6 mg/dl

Special Precautions while taking Calcitriol

1.Liver impairment
2.Renal impairment
3.Monitor plasma calcium and creatinine in patients receiving high doses

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Calcitriol

1.Management of Hypocalcaemia
2.Management of hypoparathyroidism and pseudohypoparathyroidism

Interactions for Calcitriol

N/A

Typical Dosage for Calcitriol

Adult:
Oral:
Management of hypocalcaemia:0.25mcg/day.Dosage can be increased by 0.25mcg/day at 1 - 2 month interval.Maintenance dose:0.25 - 1 mcg/ day.
Management of hypoparathyroidism and psedohypothyroidism:0.25mcg/day in the morning and dosage can be incresed at 2 - 4 week intervals.Maintenance dose: 0.5 - 2 mcg/day
Children:above 6 years:same as adult dose
Children 1 - 5 years: 0.25 - 0.75mcg/day

Schedule of Calcitriol

N/A

Storage Requirements for Calcitriol

Store in a well closed container.Protect from heat,light and moisture.Keep out of the reach of children.

Effects of Missed Dosage of Calcitriol

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.Continue the regular schedule.

Effects of Overdose of Calcitriol

Give supportive mesures and symptomatic treatment.

Calcium

About Calcium

Calcium is necessary for cardiac function, muscle contraction, nervous activity, coagulation of blood and for maintaining structural integrity of cell membranes.
Plasma concentration of calcium is kept in normal range by three endocrine factors which control metabolism of calcium. These are (a) Parathyroid hormone, (b) Calcitonin, (c) Vitamin D. Calcium in plasma is bound to albumin, is complexed with anions (e.g. phosphate) and as diffusible ionic calcium. The physiological effects are exerted by ionic calcium. The predominant source of calcium is dairy products and the daily intake varies from 200 - 2500 mg. Adequate calcium intake is particularly important during periods of bone growth in childhood and adolescence and during pregnancy and lactation.
Patients with advanced renal insufficiency exhibit phosphate retention and some degree of hyperphosphataemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy and soft tissue calcification. Calcium acetate, when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the faeces.
Deficiency signs and symptoms: Osteoporosis, pathological fractures, brittle nails and hair.

Mechanism of Action of Calcium

Calcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and
A-V conduction. Calcium is also required for blood-coagulation.

Pharmacokinets of Calcium

Absorption: Actively absorbed from gastrointestinal tract in an ionized form; and vitamin D in it`s active form is required for calcium absorption, Distribution: Distributed mainly in to skeletal tissue (99%) and 1% is distributed equally between the intracellular and extra cellular fluid. CSF levels are about half of the serum calcium levels, Metabolism: Not significantly metabolized in the body, Excretion: Excreted mainly through faeces and a small amount is excreted through urine.

Onset of Action for Calcium

N/A

Duration of Action for Calcium

N/A

Half Life of Calcium

N/A

Side Effects of Calcium

1.Constipation
2.Bloating
3.Excess gas
4.Anorexia
5.Nausea
6.Vomiting
7.Abdominal pain
8.Thirst
9.Hypercalcaemia
10.Polyuria
11.Dry mouth
12.Delirium
13.Confusion

Contra-indications of Calcium

1.Renal calculi
2.Hypophosphataemia
3.Hypercalcaemia
4.Ventricular fibrillation.

Special Precautions while taking Calcium

1.Renal impairment
2.Cardiac diseases
3.Sarcoidosis
4.Cor pulmonale
5.Respiratory acidosis
6.Respiratory failure
7.End stage renal failure
8.Hypoparathyroid patients
9.Digitalized patients
10.Prolonged use of therapeutic amounts.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Calcium

1.Hypocalcaemia
2.Calcium and vitamin D deficiency
3.Calcium deficiency during pregnancy and lactation
4.Rickets
5.Prevention of osteoporosis in postmenopausal women
6.Chronic renal failure.

Interactions for Calcium

N/A

Typical Dosage for Calcium

Oral: 500mg to 2g daily in two to four divided doses.
Hypocalcaemia:
Adults: 1g daily. Increases to 2g daily if required.
Prevention of osteoporosis: 1 to 1.5g daily.
Children: 45 to 65mg/kg daily.
Neonates: 50 to 150mg/kg and should not exceed 1g.

Schedule of Calcium

N/A

Storage Requirements for Calcium

Store in a well closed container in a cool and dry place. Protect from light.

Effects of Missed Dosage of Calcium

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Calcium

Remove calcium from stomach by induced emesis and gastric lavage. Provide symptomatic treatment and supportive measures.

Zinc Sulphate

About Zinc Sulphate

Zinc compound, An astringent , Adjunctive treatment of Wilson?s disease.

Mechanism of Action of Zinc Sulphate

N/A

Pharmacokinets of Zinc Sulphate

N/A

Onset of Action for Zinc Sulphate

N/A

Duration of Action for Zinc Sulphate

N/A

Half Life of Zinc Sulphate

N/A

Side Effects of Zinc Sulphate

N/A

Contra-indications of Zinc Sulphate

N/A

Special Precautions while taking Zinc Sulphate

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Zinc Sulphate

N/A

Interactions for Zinc Sulphate

N/A

Typical Dosage for Zinc Sulphate

N/A

Schedule of Zinc Sulphate

N/A

Storage Requirements for Zinc Sulphate

N/A

Effects of Missed Dosage of Zinc Sulphate

N/A

Effects of Overdose of Zinc Sulphate

N/A

Magnesium

About Magnesium

Magnesium is essential for enzyme activity, calcium and potassium uptake, nerve transmission, bone formation and metabolism of carbohydrates and minerals. It is magnesium, not calcium, which helps form hard tooth enamel, resistant to decay. Like calcium and chloride, magnesium also plays a role in regulating the acid-alkaline balance in the body. High magnesium levels in drinking water have been linked to resistance to heart disease. Although it is found in many foods, including dairy products, nuts, vegetables, fish, meat and seafood, deficiencies are common in America due to soil depletion, poor absorption and lack of minerals in drinking water. A diet high in carbohydrates, oxalic acid in foods like raw spinach and phytic acid found in whole grains can cause deficiencies. An excellent source of usable magnesium is beef, chicken or fish broth. High amounts of zinc and vitamin D increase magnesium requirements. Magnesium deficiency can result in coronary heart disease, chronic weight loss, obesity, fatigue, epilepsy and impaired brain function. Chocolate cravings are a sign of magnesium deficiency.

Mechanism of Action of Magnesium

N/A

Pharmacokinets of Magnesium

N/A

Onset of Action for Magnesium

N/A

Duration of Action for Magnesium

N/A

Half Life of Magnesium

N/A

Side Effects of Magnesium

N/A

Contra-indications of Magnesium

N/A

Special Precautions while taking Magnesium

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Magnesium

N/A

Interactions for Magnesium

N/A

Typical Dosage for Magnesium

N/A

Schedule of Magnesium

N/A

Storage Requirements for Magnesium

N/A

Effects of Missed Dosage of Magnesium

N/A

Effects of Overdose of Magnesium

N/A

Sodium

About Sodium

As all body fluids contain sodium, it can be said that sodium is essential to life. It is needed for many biochemical processes including water balance regulation, fluid distribution on either side of the cell walls, muscle contraction and expansion, nerve stimulation and acid-alkaline balance. Sodium is very important to the proper function of the adrenal glands. However, excessive sodium may result in high blood pressure, potassium deficiency, and liver, kidney and heart disease; symptoms of deficiency include confusion, low blood sugar, lethargy, weakness, and heart palpitations. Meat broths are excellent sources.

Mechanism of Action of Sodium

N/A

Pharmacokinets of Sodium

N/A

Onset of Action for Sodium

N/A

Duration of Action for Sodium

N/A

Half Life of Sodium

N/A

Side Effects of Sodium

N/A

Contra-indications of Sodium

N/A

Special Precautions while taking Sodium

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Sodium

N/A

Interactions for Sodium

N/A

Typical Dosage for Sodium

N/A

Schedule of Sodium

N/A

Storage Requirements for Sodium

N/A

Effects of Missed Dosage of Sodium

N/A

Effects of Overdose of Sodium

N/A

Home Delivery for Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including calcitriol + calcium + zinc sulphate + magnesium + sodium.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for calcitriol + calcium + zinc sulphate + magnesium + sodium and other medicines and health products. Home delivery services for calcitriol + calcium + zinc sulphate + magnesium + sodium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take calcitriol + calcium + zinc sulphate + magnesium + sodium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for calcitriol + calcium + zinc sulphate + magnesium + sodium before they complete the sale. You can get this information while placing the order for calcitriol + calcium + zinc sulphate + magnesium + sodium with the pharmacy.

Calcitriol + Calcium + Zinc Sulphate + Magnesium + Sodium is a generic medicine name and there are several brands available for it. Some of the brands for calcitriol + calcium + zinc sulphate + magnesium + sodium might be better known than calcitriol + calcium + zinc sulphate + magnesium + sodium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have calcitriol + calcium + zinc sulphate + magnesium + sodium in stock, you can ask for one of the branded alternatives for calcitriol + calcium + zinc sulphate + magnesium + sodium.