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- Pharmacology For Cefalexin + Carbocysteine
Cefalexin + Carbocysteine Pharmacology
Cefalexin + Carbocysteine
About Cefalexin + CarbocysteineN/AMechanism of Action of Cefalexin + CarbocysteineN/APharmacokinets of Cefalexin + CarbocysteineN/AOnset of Action for Cefalexin + CarbocysteineN/ADuration of Action for Cefalexin + CarbocysteineN/AHalf Life of Cefalexin + CarbocysteineN/ASide Effects of Cefalexin + CarbocysteineN/AContra-indications of Cefalexin + CarbocysteineN/ASpecial Precautions while taking Cefalexin + CarbocysteineN/APregnancy Related InformationContraindicated; since Carbocysteine is contraindicated in pregnancy, the combination geneic cannot be used in pregnancy.Old Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Carbocysteine is contraindicated in breast feeding, the combination geneic cannot be used in breast feeding mother.Children Related InformationN/AIndications for Cefalexin + CarbocysteineIt is a combination of first generation Cephalexin and Expectorant and mucolytic Carbocisteine.
1.Respiratory tract infections
Interactions for Cefalexin + CarbocysteineN/ATypical Dosage for Cefalexin + CarbocysteineI tablet to be taken 4 times daily.
( Each tablet contains Cephalexin 250mg + Carbocisteine 150mg or Cephalexine 500mg + Carbocisteine 150mg )
Schedule of Cefalexin + CarbocysteineN/AStorage Requirements for Cefalexin + CarbocysteineN/AEffects of Missed Dosage of Cefalexin + CarbocysteineN/AEffects of Overdose of Cefalexin + CarbocysteineN/ACefalexin
About CefalexinA first-generation cephalosporin antibiotic.Mechanism of Action of CefalexinCephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin
Pharmacokinets of CefalexinAbsorption: well absorbed orally, food delays absorption, Distribution: widely distributed, Metabolism: not metabolized, Excretion: excreted mainly through urine; & small amount is excreted in breast milkOnset of Action for CefalexinWithin 1hourDuration of Action for CefalexinUp to 12 hoursHalf Life of CefalexinN/ASide Effects of Cefalexin1.Nausea
2.Vomiting
3.Diarrhea
4.Gastritis
5.Super infections
6.Candidiasis
7.Rash & hypersensitivity reactions
8.Joint pain
9.Vaginitis
10.Neutropenia
11.Tthrombocytopenia
12.Headache
13.Dizziness
14.Hallucinations
15.Nephritis
16.Elevated liver enzymes
Contra-indications of Cefalexin1.Hypersensitivity to cephalosporins
2.Porphyria
3.Neuromuscular disorders.
Special Precautions while taking Cefalexin1.Renal impairment
2.Those allergic to penicillins
3. Neuromuscular disorders
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Cefalexin1.Respiratory tract infections
2.Urinary tract infections
3.Surgical prophylaxis
4.Skin infections`
5.Joint & bone infections
6.Otitis media`
7.Reproductive tract infections`
Interactions for CefalexinProbenecid: Excretion of cephalexin reduced.
Aminoglycosides: Enhance half-life and potentiate nephrotoxicity.Typical Dosage for CefalexinAdults: 0 .25 to 1gm orally three times daily or four times daily
Children: 25 to 100mg/kg/day orally four times daily
Infections caused by susceptible organisms:
Adults: 0.25 to 1gm orally four times daily
Children: 25 to 50mg/kg/day orally four times daily
Otitismedia:
Adults: 0.25 to 1gm orally four times daily
Children:75 to 100 mg/kg/day four times daily
Schedule of CefalexinHStorage Requirements for CefalexinStore in a cool place.Effects of Missed Dosage of CefalexinTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CefalexinSymptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measuresCarbocysteine
About CarbocysteineMucoactive drug, : local anti-infective agents, expectorants.Mechanism of Action of CarbocysteineCarbocysteine is a mucolytic which liquefies the viscid sputum. It acts on the metabolism of mucus producing cells. It induces the production of mucus with increased sialomucin content. Sialomucin influences the rheological properties of mucus and also inhibits kinins and prevents bronchial inflammation and bronchospasm. It normalizes mucus viscosity and reduces goblet cell hyperplasia.Pharmacokinets of CarbocysteineAbsorption: Administered orally.Onset of Action for CarbocysteineN/ADuration of Action for CarbocysteineN/AHalf Life of CarbocysteineN/ASide Effects of Carbocysteine1. Gastrointestinal irritation
2. Rashes
3. Headache
4. Nausea
5. Diarrhoea
6. Dizziness
7. Palpitations
8. Heartburn
9. Gastrointestinal bleedingContra-indications of Carbocysteine1. Hypersensitivity to the drug
2. Peptic ulcerSpecial Precautions while taking CarbocysteineHistory of gastric or duodenal ulcer.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Carbocysteine1. Bronchitis
2. Broncheistasis
3. Bronchial obstruction
4. Asthma
5. Upper respiratory tract congestion
6. Sinusitis
7. Rhinopharyngitis
8. Adjunctive therapy in respiratory tract disorders with excessive viscous mucous in the absence of infectionInteractions for CarbocysteineN/ATypical Dosage for CarbocysteineAdults: 500 to 750mg thrice daily.
Children (5 to 12 years): 250mg thrice daily.
Children (2 to 5 years): 125mg two to four times daily as required.
Schedule of CarbocysteineHStorage Requirements for CarbocysteineStore at a temperature below 25 degree C. Protect from light. Keep out of reach of children.Effects of Missed Dosage of CarbocysteineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CarbocysteineProvide symptomatic treatment and supportive measures.Home Delivery for Cefalexin + Carbocysteine in Your City
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Cefalexin + Carbocysteine is a generic medicine name and there are several brands available for it. Some of the brands for cefalexin + carbocysteine might be better known than cefalexin + carbocysteine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefalexin + carbocysteine in stock, you can ask for one of the branded alternatives for cefalexin + carbocysteine.