Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine Pharmacology

Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

About Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Mechanism of Action of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Pharmacokinets of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Onset of Action for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Duration of Action for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Half Life of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Side Effects of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Contra-indications of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Special Precautions while taking Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Pregnancy Related Information

Use with caution

Old Age Related Information

N/A

Breast Feeding Related Information

Use with caution

Children Related Information

N/A

Indications for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

1.For treatment of nerve and muscle disorders
2.For the treatment of Diabetic neuropathy
3.Nutritional supplement

Interactions for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Typical Dosage for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Schedule of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Storage Requirements for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Effects of Missed Dosage of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Effects of Overdose of Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine

N/A

Folic Acid

About Folic Acid

Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.

Mechanism of Action of Folic Acid

Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.

Pharmacokinets of Folic Acid

Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.

Onset of Action for Folic Acid

Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes

Duration of Action for Folic Acid

Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours

Half Life of Folic Acid

N/A

Side Effects of Folic Acid

N/A

Contra-indications of Folic Acid

N/A

Special Precautions while taking Folic Acid

1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient

Pregnancy Related Information

May be used

Old Age Related Information

May be used

Breast Feeding Related Information

May be used

Children Related Information

May be used

Indications for Folic Acid

1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue

Interactions for Folic Acid

1. Hypersensitivity reactions with injection form
2. Bronchospasm

Typical Dosage for Folic Acid

Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.

Schedule of Folic Acid

C1 (Oral)
C (Parenteral)

Storage Requirements for Folic Acid

Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.

Effects of Missed Dosage of Folic Acid

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Folic Acid

Relatively non toxic. Provide symptomatic treatment and supportive measures.

Pyridoxine

About Pyridoxine

Water soluble vitamin(Vit B6), In Vitamin B6 deficiency ,Neuropathy.

Mechanism of Action of Pyridoxine

N/A

Pharmacokinets of Pyridoxine

N/A

Onset of Action for Pyridoxine

N/A

Duration of Action for Pyridoxine

N/A

Half Life of Pyridoxine

N/A

Side Effects of Pyridoxine

N/A

Contra-indications of Pyridoxine

N/A

Special Precautions while taking Pyridoxine

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Pyridoxine

N/A

Interactions for Pyridoxine

N/A

Typical Dosage for Pyridoxine

N/A

Schedule of Pyridoxine

N/A

Storage Requirements for Pyridoxine

N/A

Effects of Missed Dosage of Pyridoxine

N/A

Effects of Overdose of Pyridoxine

N/A

Mecobalamin

About Mecobalamin

Water soluble, Form of Vitamin B12

Mechanism of Action of Mecobalamin

Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Pharmacokinets of Mecobalamin

Absorption: Absorbed after oral, sublingual, injection
Excretion: Excretion via urine

Onset of Action for Mecobalamin

N/A

Duration of Action for Mecobalamin

N/A

Half Life of Mecobalamin

N/A

Side Effects of Mecobalamin

1.Oral: Anorexia, nausea, vomiting and diarrhea
2.Parenteral: Rash, headache, hot sensation, diaphoresis and pain/induration at IM inj site

Contra-indications of Mecobalamin

N/A

Special Precautions while taking Mecobalamin

N/A

Pregnancy Related Information

May be used

Old Age Related Information

May be used

Breast Feeding Related Information

May be used

Children Related Information

N/A

Indications for Mecobalamin

1.Peripheral neuropathies
2.Megaloblastic anaemia

Interactions for Mecobalamin

1.Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicines
2.Reduced serum concentrations with oral contraceptives
3.Reduced effects in anaemia with parenteral chloramphenicol

Typical Dosage for Mecobalamin

Peripheral neuropathies
Oral: Adult: 1500 mcg/day in 3 divided doses
Parenteral: 500 mcg daily IM/IV 3 times/wk

Megaloblastic anaemia caused by vitamin B12 deficiency
Parenteral: Adult: 500 mcg daily IM/IV 3 times/wk. Maintenance dose: After about 2 mth of therapy, reduce dose to single admin of 500 mcg every 1-3 mth.

Schedule of Mecobalamin

N/A

Storage Requirements for Mecobalamin

Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.

Effects of Missed Dosage of Mecobalamin

N/A

Effects of Overdose of Mecobalamin

N/A

About

N/A

Mechanism of Action of

N/A

Pharmacokinets of

N/A

Onset of Action for

N/A

Duration of Action for

N/A

Half Life of

N/A

Side Effects of

N/A

Contra-indications of

N/A

Special Precautions while taking

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for

N/A

Interactions for

N/A

Typical Dosage for

N/A

Schedule of

N/A

Storage Requirements for

N/A

Effects of Missed Dosage of

N/A

Effects of Overdose of

N/A

Biotin

About Biotin

N/A

Mechanism of Action of Biotin

Biotin excerts it`s pharmacological action by influencing metabolic reactions. It acts as a coenzyme for carbohydrate, fat, and protein metabolism. It is required for cell growth and production of fatty acids. It is required for healthy maintenance of hair, skin, sweat glands, nerve tissue, and bone marrow. It also helps in the transfer of carbon dioxide and in the maintenance of a steady blood sugar level.

Pharmacokinets of Biotin

Absorption: Well absorbed orally, Excretion: Extra drug is excreted unchanged in urine.

Onset of Action for Biotin

N/A

Duration of Action for Biotin

N/A

Half Life of Biotin

N/A

Side Effects of Biotin

N/A

Contra-indications of Biotin

Hypersensitivity of any biotin products.

Special Precautions while taking Biotin

N/A

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Biotin

1.Biotin deficiency
2 Alopecia
3.Brittle nails
4.Prevent diabetic neuropathy and lower blood glucose levels in diabetic patients
5.Seborrheic dermatitis
6.Dry skin.

Interactions for Biotin

N/A

Typical Dosage for Biotin

Oral: 30 to 70mcg daily. Increased up to 300mcg/day if required based on the severity of deficiency.
Pregnancy: 30mcg daily
Lactation: 35mcg daily
Prevent brittle nails: 2.5mg/day.

Schedule of Biotin

Storage Requirements for Biotin

Store in a cool dry area in a well closed container. Protects from moisture, light and direct heat.

Effects of Missed Dosage of Biotin

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Biotin

Provide symptomatic treatment and supportive measures.

Benfotiamine

About Benfotiamine

Synthetic S-acyl derivative of thiamine (vitamine B1), Antioxidant ,anti-AGE(Advanced glycation end product) supplement, Treating Diabetic Complications.

Mechanism of Action of Benfotiamine

N/A

Pharmacokinets of Benfotiamine

N/A

Onset of Action for Benfotiamine

N/A

Duration of Action for Benfotiamine

N/A

Half Life of Benfotiamine

N/A

Side Effects of Benfotiamine

N/A

Contra-indications of Benfotiamine

N/A

Special Precautions while taking Benfotiamine

N/A

Pregnancy Related Information

N/A

Old Age Related Information

N/A

Breast Feeding Related Information

N/A

Children Related Information

N/A

Indications for Benfotiamine

1.Management of diabetic neuropathy, diabetic nephropathy and diabetic retinopathy
2.Beri Beri
3.Wenicke-korsakoff syndrome

Interactions for Benfotiamine

N/A

Typical Dosage for Benfotiamine

N/A

Schedule of Benfotiamine

N/A

Storage Requirements for Benfotiamine

N/A

Effects of Missed Dosage of Benfotiamine

N/A

Effects of Overdose of Benfotiamine

N/A

Home Delivery for Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine and other medicines and health products. Home delivery services for folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine before they complete the sale. You can get this information while placing the order for folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine with the pharmacy.

Folic Acid + Pyridoxine + Mecobalamin + Alpha LipoicAcid + Biotin + Benfotiamine is a generic medicine name and there are several brands available for it. Some of the brands for folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine might be better known than folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine in stock, you can ask for one of the branded alternatives for folic acid + pyridoxine + mecobalamin + alpha lipoicacid + biotin + benfotiamine.