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- Pharmacology For Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12
Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12 Pharmacology
Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12
About Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AMechanism of Action of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/APharmacokinets of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AOnset of Action for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/ADuration of Action for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AHalf Life of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/ASide Effects of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AContra-indications of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/ASpecial Precautions while taking Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B121.Antioxidant
2.Nutritional supplement
Interactions for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/ATypical Dosage for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/ASchedule of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AStorage Requirements for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AEffects of Missed Dosage of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AEffects of Overdose of Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12N/AAbout N/AMechanism of Action of N/APharmacokinets of N/AOnset of Action for N/ADuration of Action for N/AHalf Life of N/ASide Effects of N/AContra-indications of N/ASpecial Precautions while taking N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for N/AInteractions for N/ATypical Dosage for N/ASchedule of N/AStorage Requirements for N/AEffects of Missed Dosage of N/AEffects of Overdose of N/ALycopene
About LycopeneCarotenoid;Terpenes and terpenoids, Dietary antioxidant.Mechanism of Action of LycopeneN/APharmacokinets of LycopeneN/AOnset of Action for LycopeneN/ADuration of Action for LycopeneN/AHalf Life of LycopeneN/ASide Effects of LycopeneN/AContra-indications of LycopeneN/ASpecial Precautions while taking LycopeneN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for LycopeneN/AInteractions for LycopeneN/ATypical Dosage for LycopeneN/ASchedule of LycopeneN/AStorage Requirements for LycopeneN/AEffects of Missed Dosage of LycopeneN/AEffects of Overdose of LycopeneN/AEicosapentaenoic Acid
About Eicosapentaenoic AcidAn omega-3 fatty acid, Essential fatty acid, dietary supplement, Anti atherosclerotic.Mechanism of Action of Eicosapentaenoic AcidEicosapentaenoic acid is an omega-3 fatty acid. It is found with Docosapentaenoic acid. Omega-3 fatty acids are of polyunsaturated fatty acids that derives from food. They help to lower triglycerides and cholesterol and increase HDL cholesterol (the Good cholesterol) and thus improves lipid profile. Omega 3 fatty acids may also act as an anticoagulant to prevent blood clotting. They have anti-inflammatory actions and also lower high blood pressure. The incorporation of Omega-3 fatty acids in the membranes of the cells increases the physicochemical stability and functional integrity. It also makes the cells less susceptible to oxidative damage and also decreases the formation of lipid peroxidases. They protect from cardiovascular disorders and may also reduce the risks and symptoms for other disorders including diabetes, dementia, rheumatoid arthritis, asthma, stroke, inflammatory bowel disease, ulcerative colitis, mental decline, and some cancers. They aid in proper functioning of central nervous system.
Hypolipidaemic action: It produces a reduction in plasma triglycerides by reducing bad cholesterol or very low density lipoproteins.
Antiinflammatory action: Omega - 3 fatty acids are long chain poly unsaturated fatty acids.They compete with arachidonic acid for cyclo-oxygenase and lipoxygenase They inhibits inflammatory mediators by inhibiting leukotriene synthesis pathway.
Antithrombotic effect: They promote vasodilatation, a reduction in platelet aggregation, increased bleeding time and decreased platelet counts
Pharmacokinets of Eicosapentaenoic AcidN/AOnset of Action for Eicosapentaenoic AcidN/ADuration of Action for Eicosapentaenoic AcidN/AHalf Life of Eicosapentaenoic AcidN/ASide Effects of Eicosapentaenoic Acid1.Loose stools
2.Abdominal discomfort
3.Belching
4.Prolong bleeding time slightly
5.Nausea
6.Vomiting
7.DiarrhoeaContra-indications of Eicosapentaenoic AcidHypersensitivity to the drugSpecial Precautions while taking Eicosapentaenoic Acid1.Haemorrhagic disorders
2.Patient on anticoagulants therapy
3.Hepatic impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
Infants:ContraindicatedIndications for Eicosapentaenoic Acid1.Coronary artery disease
2.Hypertension
3.Atherosclerosis related disorders
4.Obesity
5.Fatty diet
6.Hyperlipidaemia
7.Smoking
8.Diabetes
Interactions for Eicosapentaenoic AcidN/ATypical Dosage for Eicosapentaenoic Acid180mg once or twice dailySchedule of Eicosapentaenoic AcidN/AStorage Requirements for Eicosapentaenoic AcidStore in airtight containers. Protect from light.
Effects of Missed Dosage of Eicosapentaenoic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Eicosapentaenoic AcidGive supportive measures and symptomatic treatment.Docosahexenoic Acid
About Docosahexenoic AcidAn omega-3 fatty acid(polyunsaturated fatty acids, PUFAs), An essential fatty acid, brain food ,Antiatherosclerotic.Mechanism of Action of Docosahexenoic AcidIt is found with Eicosapentaenoic acid. Omega-3 fatty acids are of polyunsaturated fatty acids that derives from food. They help to lower triglycerides and cholesterol and increase HDL cholesterol (the Good cholesterol) and thus improves lipid profile. Omega 3 fatty acids may also act as an anticoagulant to prevent blood clotting. They have anti-inflammatory actions and also lower high blood pressure. The incorporation of Omega-3 fatty acids in the membranes of the cells increases the physicochemical stability and functional integrity. It also makes the cells less susceptible to oxidative damage and also decreases the formation of lipid peroxidases. They protect from cardiovascular disorders and may also reduce the risks and symptoms for other disorders including diabetes, dementia, rheumatoid arthritis, asthma, stroke, inflammatory bowel disease, ulcerative colitis, mental decline, and some cancers. They aid in proper functioning of central nervous system.
Hypolipidaemic action: It produces a reduction in plasma triglycerides by reducing bad cholesterol or very low density lipoproteins.
Antiinflammatory action: Omega - 3 fatty acids are long chain poly unsaturated fatty acids.They compete with arachidonic acid for cyclo-oxygenase and lipoxygenase They inhibits inflammatory mediators by inhibiting leukotriene synthesis pathway.
Antithrombotic effect: They promote vasodilatation, a reduction in platelet aggregation, increased bleeding time and decreased platelet counts
Pharmacokinets of Docosahexenoic AcidN/AOnset of Action for Docosahexenoic AcidN/ADuration of Action for Docosahexenoic AcidN/AHalf Life of Docosahexenoic AcidN/ASide Effects of Docosahexenoic Acid1.Loose stools
2.Abdominal discomfort
3.Belching
4.Prolong bleeding time slightly
5.Nausea
6.Vomiting
7.Diarrhoea
8.Constipation
Contra-indications of Docosahexenoic AcidHypersensitivity to the drugSpecial Precautions while taking Docosahexenoic Acid1.Haemorrhagic disorders
2.Patient on anticoagulants therapy
3.Hepatic impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
Infants: ContraindicatedIndications for Docosahexenoic Acid1.Coronary artery disease
2.Hypertension
3.Atherosclerosis related disorders
4.Obesity
5.Fatty diet
6.Hyperlipidaemia
7.Smoking
8.Diabetes
Interactions for Docosahexenoic AcidN/ATypical Dosage for Docosahexenoic Acid120 - 240 mg / day in single or 2 divided dose with Eicosapentaenoic acid.Schedule of Docosahexenoic AcidN/AStorage Requirements for Docosahexenoic AcidStore in airtight containers. Protect from light.
Effects of Missed Dosage of Docosahexenoic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Docosahexenoic AcidGive supportive measures and symptomatic treatment.Selenium
About SeleniumA vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.Mechanism of Action of SeleniumN/APharmacokinets of SeleniumN/AOnset of Action for SeleniumN/ADuration of Action for SeleniumN/AHalf Life of SeleniumN/ASide Effects of SeleniumN/AContra-indications of SeleniumN/ASpecial Precautions while taking SeleniumN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for SeleniumN/AInteractions for SeleniumN/ATypical Dosage for SeleniumN/ASchedule of SeleniumN/AStorage Requirements for SeleniumN/AEffects of Missed Dosage of SeleniumN/AEffects of Overdose of SeleniumN/AVitamin C
About Vitamin CWater soluble vitamin, antioxidant.Mechanism of Action of Vitamin CVitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.Pharmacokinets of Vitamin CAbsorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin CN/ADuration of Action for Vitamin CN/AHalf Life of Vitamin CN/ASide Effects of Vitamin C1. Discomfort at injection site
2. Acid urine
3. Renal calculi
4. Oxaluria
Contra-indications of Vitamin CNo known contraindicationsSpecial Precautions while taking Vitamin C1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Vitamin C1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries
Interactions for Vitamin COral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.Typical Dosage for Vitamin COral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Scurvy:
Oral:
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.
Schedule of Vitamin CC1 (Oral)
C (Parenteral)Storage Requirements for Vitamin CStore in a cool dry area in a well closed container. Protects from moisture, light and direct heat.Effects of Missed Dosage of Vitamin CTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin CDiscontinue the therapy and provide symptomatic and supportive measures.Zinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresVit B12
About Vit B12N/AMechanism of Action of Vit B12Vitamin B12 is an essential constituent for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Vitamin B12 is converted in to coenzyme B12 in the tissues which is essential for conversion of methyl-malonate to succinate and synthesis of methionine from homocystine. It is also associated with fat and carbohydrate metabolism and protein synthesis. Cells characterized by rapid division such as epithelial cells, bone marrow, and myeloid cells appear to have greatest requirement of Cyanocobalamin.Pharmacokinets of Vit B12Absorption: Absorbed irregularly after oral administration and absorption depends on Ca and intrinsic factor. It is also administered subcutaneously and intramuscularly.
Distribution: Distributed in to liver, bone marrow, and other tissues. It crosses the placenta and appears in breast milk.
Metabolism: It is metabolized in liver.
Excretion: In normal dosage it is reabsorbed from bile and a minute portion is excreted through urine but the extra drug is excreted through urine.
Onset of Action for Vit B12N/ADuration of Action for Vit B12N/AHalf Life of Vit B12N/ASide Effects of Vit B121. Anaphylaxis
2. Anaphylactoid reactions
3. Pain and burning sensation at injection site
4. Itching
5. Urticaria
6. Transient diarrhea
7. Peripheral vascular thrombosis
8. Pulmonary oedema
Contra-indications of Vit B121. Hypersensitivity to the drug
2. Leber`s disease
Special Precautions while taking Vit B121. Anemic patients with coexisting cardiac, pulmonary and hypertensive diseases.Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationUse with caution
NEONATES : Use with caution
Indications for Vit B121. Vitamin B12 deficiency
2. Pernicious Anaemia
3. Peripheral neuropathy (diabetic, alcoholic, and drug induced)
Interactions for Vit B12N/ATypical Dosage for Vit B12I.M., S.C.:
Pernicious Anaemia: 100mcg daily for 1 week followed by the same dose given on alternate days for 7 doses and then every 3 to 4days for another 3 weeks. This regimen should be followed by 100mcg monthly for life. Concurrently administer folic acid if required.
Vitamin B12 deficiency other than pernicious Anaemia: 30mcg daily for 5 to 10days depending up on the severity of the condition.
Maintenance dosage: 100 to 200mcg once monthly.
Children: 100mcg I.M. or S.C. over the course of 2 or more weeks.
Maintenance dosage: 60mcg monthly I.M. or S.C.
Schilling test flushing dose:
Adults and Children: 1000mcg I.M. in single dose
Recommended RDA (recommended dietary allowance) for Vitamin B12:
Infants up to 6months of age: 0.3mcg.
Children age 6 months to 1 year: 0.5mcg.
Children age 1 to 3: 0.7mcg.
Children age 4 to 6: 1mcg.
Children age 7 to 10: 1.4mcg.
Children age 11 to adult: 2mcg..
Pregnant women: 2.2mcg.
Breast feeding women: 2.6mcg.
Schedule of Vit B12CStorage Requirements for Vit B12Store at room temperature range of 15 to 30 degree C.in a light resistant well closed container in a dry place.Effects of Missed Dosage of Vit B12Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vit B12Not applicable. Even in large doses Vitamin B12 isn`t usually toxic.Home Delivery for Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12 in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 and other medicines and health products. Home delivery services for coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 before they complete the sale. You can get this information while placing the order for coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 with the pharmacy.
Coenzyme Q10 + Lycopene + Eicosapentaenoic Acid +Docosahexenoic Acid + Selenium + Vitamin C + Zinc +Vit B12 is a generic medicine name and there are several brands available for it. Some of the brands for coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 might be better known than coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12 in stock, you can ask for one of the branded alternatives for coenzyme q10 + lycopene + eicosapentaenoic acid +docosahexenoic acid + selenium + vitamin c + zinc +vit b12.