Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline Pharmacology

Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline

About Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Mechanism of Action of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Pharmacokinets of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Onset of Action for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Duration of Action for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Half Life of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Side Effects of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Contra-indications of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Special Precautions while taking Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
Nutritional supplement
Interactions for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Typical Dosage for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Schedule of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Storage Requirements for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Effects of Missed Dosage of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Effects of Overdose of Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline
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Folic Acid

About Folic Acid
Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.
Mechanism of Action of Folic Acid
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Pharmacokinets of Folic Acid
Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic Acid
Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic Acid
Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic Acid
N/A
Side Effects of Folic Acid
N/A
Contra-indications of Folic Acid
N/A
Special Precautions while taking Folic Acid
1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Folic Acid
1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid
1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic Acid
Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic Acid
C1 (Oral)
C (Parenteral)
Storage Requirements for Folic Acid
Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.
Effects of Missed Dosage of Folic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Folic Acid
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Vitamin E

About Vitamin E
N/A
Mechanism of Action of Vitamin E
Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.
Pharmacokinets of Vitamin E
Absorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.
Onset of Action for Vitamin E
N/A
Duration of Action for Vitamin E
N/A
Half Life of Vitamin E
N/A
Side Effects of Vitamin E
1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence


Contra-indications of Vitamin E
1. Hypersensitivity to the drug
2. Should not administer intravenously
Special Precautions while taking Vitamin E
1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens
Pregnancy Related Information
May be used
Old Age Related Information
N/A
Breast Feeding Related Information
May be used
Children Related Information
N/A
Indications for Vitamin E
1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant


Interactions for Vitamin E
Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.

Typical Dosage for Vitamin E
Oral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.



Schedule of Vitamin E
C1
Storage Requirements for Vitamin E
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Vitamin E
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vitamin E
Provide supportive measures and symptomatic treatment.

Selenium

About Selenium
A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.
Mechanism of Action of Selenium
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Pharmacokinets of Selenium
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Onset of Action for Selenium
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Duration of Action for Selenium
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Half Life of Selenium
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Side Effects of Selenium
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Contra-indications of Selenium
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Special Precautions while taking Selenium
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Selenium
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Interactions for Selenium
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Typical Dosage for Selenium
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Schedule of Selenium
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Storage Requirements for Selenium
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Effects of Missed Dosage of Selenium
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Effects of Overdose of Selenium
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Pyridoxine

About Pyridoxine
Water soluble vitamin(Vit B6), In Vitamin B6 deficiency ,Neuropathy.
Mechanism of Action of Pyridoxine
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Pharmacokinets of Pyridoxine
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Onset of Action for Pyridoxine
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Duration of Action for Pyridoxine
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Half Life of Pyridoxine
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Side Effects of Pyridoxine
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Contra-indications of Pyridoxine
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Special Precautions while taking Pyridoxine
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Pyridoxine
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Interactions for Pyridoxine
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Typical Dosage for Pyridoxine
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Schedule of Pyridoxine
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Storage Requirements for Pyridoxine
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Effects of Missed Dosage of Pyridoxine
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Effects of Overdose of Pyridoxine
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Vitamin C

About Vitamin C
Water soluble vitamin, antioxidant.
Mechanism of Action of Vitamin C
Vitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.
Pharmacokinets of Vitamin C
Absorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin C
N/A
Duration of Action for Vitamin C
N/A
Half Life of Vitamin C
N/A
Side Effects of Vitamin C
1. Discomfort at injection site
2. Acid urine
3. Renal calculi
4. Oxaluria
Contra-indications of Vitamin C
No known contraindications
Special Precautions while taking Vitamin C
1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
May be used
Indications for Vitamin C
1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries

Interactions for Vitamin C
Oral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.
Typical Dosage for Vitamin C
Oral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Scurvy:
Oral:
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.

Schedule of Vitamin C
C1 (Oral)
C (Parenteral)
Storage Requirements for Vitamin C
Store in a cool dry area in a well closed container. Protects from moisture, light and direct heat.
Effects of Missed Dosage of Vitamin C
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vitamin C
Discontinue the therapy and provide symptomatic and supportive measures.

Lycopene

About Lycopene
Carotenoid;Terpenes and terpenoids, Dietary antioxidant.
Mechanism of Action of Lycopene
N/A
Pharmacokinets of Lycopene
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Onset of Action for Lycopene
N/A
Duration of Action for Lycopene
N/A
Half Life of Lycopene
N/A
Side Effects of Lycopene
N/A
Contra-indications of Lycopene
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Special Precautions while taking Lycopene
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Lycopene
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Interactions for Lycopene
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Typical Dosage for Lycopene
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Schedule of Lycopene
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Storage Requirements for Lycopene
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Effects of Missed Dosage of Lycopene
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Effects of Overdose of Lycopene
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Choline

About Choline
A water-soluble essential nutrient, natural quaternary saturated amine.
Mechanism of Action of Choline
Choline is a water-soluble vitamin. Choline aids in nerve transmission and utilization of fat and hormone production. It also maintain normal kidney and bladder function.
It is most effective with Vitamin A, B-Complex, B-12, Folic Acid, and Inositol. Also, it helps lower cholesterol, transferring nerve impulse to the brain, helps against memory loss and senile dementia, and aids the liver in removing poisons and drugs from the bloodstream.
Pharmacokinets of Choline
Absorption: Choline is readily absorbed throughout the small intestine.
Onset of Action for Choline
N/A
Duration of Action for Choline
N/A
Half Life of Choline
N/A
Side Effects of Choline
1.Breathing problems
2.Chest pain
3.Skin hives
4.Rash
5.Upset stomach
Contra-indications of Choline
Hypersensitivity to Choline
Special Precautions while taking Choline
N/A
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
May be used
Indications for Choline
1.Headache
2.Head injury
3.Hemiplegia
4.Memory loss
5.Neurological dysfunction
6.Seizure
7.Stroke
8.Tardive dyskinesia
Interactions for Choline
N/A
Typical Dosage for Choline
300mg, 3 times a day.
Schedule of Choline
N/A
Storage Requirements for Choline
Store in cool (<30 degree C) and dark place
Effects of Missed Dosage of Choline
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Choline
Give symptomatic and supportive treatment

Home Delivery for Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline in Your City

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Folic Acid + Vitamin E + Selenium + Pyridoxine + Vitamin C + Lycopene + Choline is a generic medicine name and there are several brands available for it. Some of the brands for folic acid + vitamin e + selenium + pyridoxine + vitamin c + lycopene + choline might be better known than folic acid + vitamin e + selenium + pyridoxine + vitamin c + lycopene + choline itself. If the pharmacy that's willing to deliver medicines to your home doesn't have folic acid + vitamin e + selenium + pyridoxine + vitamin c + lycopene + choline in stock, you can ask for one of the branded alternatives for folic acid + vitamin e + selenium + pyridoxine + vitamin c + lycopene + choline.