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- Pharmacology For Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + Selenium
Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + Selenium Pharmacology
Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + Selenium
About Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AMechanism of Action of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/APharmacokinets of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AOnset of Action for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/ADuration of Action for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AHalf Life of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/ASide Effects of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AContra-indications of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/ASpecial Precautions while taking Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + Selenium1.Nutritional supplement
2.Antioxidant
Interactions for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/ATypical Dosage for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/ASchedule of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AStorage Requirements for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AEffects of Missed Dosage of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AEffects of Overdose of Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + SeleniumN/AZinc
About ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measuresAbout N/AMechanism of Action of N/APharmacokinets of N/AOnset of Action for N/ADuration of Action for N/AHalf Life of N/ASide Effects of N/AContra-indications of N/ASpecial Precautions while taking N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for N/AInteractions for N/ATypical Dosage for N/ASchedule of N/AStorage Requirements for N/AEffects of Missed Dosage of N/AEffects of Overdose of N/AVitamin C
About Vitamin CWater soluble vitamin, antioxidant.Mechanism of Action of Vitamin CVitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.Pharmacokinets of Vitamin CAbsorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin CN/ADuration of Action for Vitamin CN/AHalf Life of Vitamin CN/ASide Effects of Vitamin C1. Discomfort at injection site
2. Acid urine
3. Renal calculi
4. Oxaluria
Contra-indications of Vitamin CNo known contraindicationsSpecial Precautions while taking Vitamin C1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Vitamin C1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries
Interactions for Vitamin COral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.Typical Dosage for Vitamin COral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Scurvy:
Oral:
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.
Schedule of Vitamin CC1 (Oral)
C (Parenteral)Storage Requirements for Vitamin CStore in a cool dry area in a well closed container. Protects from moisture, light and direct heat.Effects of Missed Dosage of Vitamin CTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin CDiscontinue the therapy and provide symptomatic and supportive measures.Lycopene
About LycopeneCarotenoid;Terpenes and terpenoids, Dietary antioxidant.Mechanism of Action of LycopeneN/APharmacokinets of LycopeneN/AOnset of Action for LycopeneN/ADuration of Action for LycopeneN/AHalf Life of LycopeneN/ASide Effects of LycopeneN/AContra-indications of LycopeneN/ASpecial Precautions while taking LycopeneN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for LycopeneN/AInteractions for LycopeneN/ATypical Dosage for LycopeneN/ASchedule of LycopeneN/AStorage Requirements for LycopeneN/AEffects of Missed Dosage of LycopeneN/AEffects of Overdose of LycopeneN/AVitamin E
About Vitamin EN/AMechanism of Action of Vitamin EVitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.Pharmacokinets of Vitamin EAbsorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.
Onset of Action for Vitamin EN/ADuration of Action for Vitamin EN/AHalf Life of Vitamin EN/ASide Effects of Vitamin E1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence
Contra-indications of Vitamin E1. Hypersensitivity to the drug
2. Should not administer intravenously
Special Precautions while taking Vitamin E1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens
Pregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Vitamin E1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant
Interactions for Vitamin EOral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.
Typical Dosage for Vitamin EOral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.
Schedule of Vitamin EC1Storage Requirements for Vitamin EStore in a well closed container in a cool dry place. Protect from light.Effects of Missed Dosage of Vitamin ETake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin EProvide supportive measures and symptomatic treatment.Selenium
About SeleniumA vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.Mechanism of Action of SeleniumN/APharmacokinets of SeleniumN/AOnset of Action for SeleniumN/ADuration of Action for SeleniumN/AHalf Life of SeleniumN/ASide Effects of SeleniumN/AContra-indications of SeleniumN/ASpecial Precautions while taking SeleniumN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for SeleniumN/AInteractions for SeleniumN/ATypical Dosage for SeleniumN/ASchedule of SeleniumN/AStorage Requirements for SeleniumN/AEffects of Missed Dosage of SeleniumN/AEffects of Overdose of SeleniumN/AHome Delivery for Zinc + Vitamin A + Vitamin C + Lycopene + Vitamin E + Selenium in Your City
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