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- Pharmacology For Clotrimazole + Menthol + Ichthammol + Zinc oxide
Clotrimazole + Menthol + Ichthammol + Zinc oxide Pharmacology
Clotrimazole + Menthol + Ichthammol + Zinc oxide
About Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AMechanism of Action of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/APharmacokinets of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AOnset of Action for Clotrimazole + Menthol + Ichthammol + Zinc oxideN/ADuration of Action for Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AHalf Life of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/ASide Effects of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AContra-indications of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/ASpecial Precautions while taking Clotrimazole + Menthol + Ichthammol + Zinc oxideN/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Clotrimazole + Menthol + Ichthammol + Zinc oxideTopical fungal infectionsInteractions for Clotrimazole + Menthol + Ichthammol + Zinc oxideN/ATypical Dosage for Clotrimazole + Menthol + Ichthammol + Zinc oxideN/ASchedule of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AStorage Requirements for Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AEffects of Missed Dosage of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AEffects of Overdose of Clotrimazole + Menthol + Ichthammol + Zinc oxideN/AClotrimazole
About ClotrimazoleA broad-spectrum antifungal antibiotic, imidazole derivative, Oral Nonabsorbed Antifungal Agent.Mechanism of Action of ClotrimazoleClotrimazole is fungicidal or fungistatic depending on the drug concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis which is an essential constituent of cell membrane. Inhibition of ergosterol synthesis will alter the membrane permeability of the susceptible fungus and kill or inhibit them.Pharmacokinets of ClotrimazoleAbsorption: Absorption is minimal after topical administration.Onset of Action for ClotrimazoleN/ADuration of Action for Clotrimazole3 hoursHalf Life of ClotrimazoleN/ASide Effects of Clotrimazole1.Stinging
2.Erythema
3.Burning
4.Pruritis
5.Vesication
6.Desquamation
7.Urticaria
8.Burning
9.Peeling
10.Irritation
Contra-indications of ClotrimazoleHypersensitivity to ClotrimazoleSpecial Precautions while taking Clotrimazole1.Avoid contact with eyes, nose and mouth.
2.Do not wear occlusive dress over the medicament.
Pregnancy Related InformationUse with caution.Old Age Related InformationUse with caution.Breast Feeding Related InformationUse with caution.Children Related InformationUse with caution.
NEONATES: contraindicatedIndications for Clotrimazole1.Tinea pedis
2.Tinea cruris
3.Tinea versicolor
4.Tinea corporis
5.Cutaneous candidiasis
6.Vulvovaginal candidiasis
Interactions for ClotrimazolePolyene Antibiotics : Antagonises effects of polyene antibiotics.Typical Dosage for ClotrimazoleTopical: Clotrimazole cream, lotion and solution 1 % is used.
Clean and dry the affected area and apply the medicament with gentle massage 2 -3 times daily for 2 - 4 weeks.
Vaginal candidiasis: Insert 1 applicator full (vaginal cream 1%) intravaginally at night for 1 -2 weeks.
Vaginal tablets 100. 200 and 500mg tablet is available.
Vulvovaginal candidiasis: Insert 100mg tablet intravaginally at bed time for 7 consecutive days or 200 mg tablet for 3 consecutive days or 500 mg tablet for 1 day at night.
Oral lozenge 10 mg is available
Oropharyngeal candidiasis: 1 lozenge orally 5 times daily for 2 weeks
Prophylaxis of Oropharyngeal candidiasis: 1 lozenge is used 3 times daily
Gel: Insert with an applicator intravaginally at night for 1 - 2 weeks.
Powder (1% w/ w): dusted over the body parts as required
Schedule of ClotrimazoleHStorage Requirements for ClotrimazoleStore at room temperature (15 - 25 degree C). Protect from heat and moisture. Keep out of the reach of childrenEffects of Missed Dosage of ClotrimazoleApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ClotrimazoleGive supportive measures and symptomatic treatment.Menthol
About MentholTerpenes and terpenoid, Antipruritic, decongestant, topical analgesic.Mechanism of Action of MentholMenthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and mild local anaesthetic effect relieves itching. It has good soothing effect and acts as a demulcent. It also acts as a carminative.Pharmacokinets of MentholN/AOnset of Action for MentholN/ADuration of Action for MentholN/AHalf Life of MentholN/ASide Effects of Menthol1.Irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
12.Contact dermatitis
13.Allergic reactions
Contra-indications of Menthol1. Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Menthol1.Should not apply Menthol directly in to or near the nostrils of small children or asthma patients
2.Prolonged use
3.Seizures
4.Should not take steam inhalation orally
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with caution
Children Related InformationUse with caution
below 2 years: ContraindicatedIndications for Menthol1. Rubefacient.
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5.Sore throat
6.Cold sores
7.Hay fever
8.As an inhalant to relieve nasal, bronchial, or upper respiratory congestion
9.Sinusitis
10.Bronchial cough
11.Pharyngeal inflammation
Interactions for MentholN/ATypical Dosage for MentholDosage individualized based on requirements of the patient.
Lozenges: Dissolve lozenge (5%-10% menthol) slowly in the mouth hourly as needed by the patients.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Menthol (3.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1tsp of solution for each pint, up to thrice daily
Schedule of MentholN/AStorage Requirements for MentholStore at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.Effects of Missed Dosage of MentholTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MentholProvide symptomatic treatment and supportive measures.Ichthammol
About IchthammolAnti psoriatic, Skin ApplicationMechanism of Action of IchthammolN/APharmacokinets of IchthammolAbsorption: Topical absorptionOnset of Action for IchthammolN/ADuration of Action for IchthammolN/AHalf Life of IchthammolN/ASide Effects of Ichthammol1.Irritant reactions
2.Hypersensitivity
Contra-indications of IchthammolHypersensitivity to these drugsSpecial Precautions while taking Ichthammol1.Not used for eye
2.Not be used in deep wounds
3.External use only
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Ichthammol1.Inflammatory skin disease
2.Psoriasis
3.Otitis Externa
4.Cervicitis
5.Vaginitis
Interactions for IchthammolN/ATypical Dosage for IchthammolAs recommendedSchedule of IchthammolN/AStorage Requirements for IchthammolStore in a well closed container, below 30 degree celcius. Keep out of the reach of childrenEffects of Missed Dosage of IchthammolN/AEffects of Overdose of IchthammolN/AZinc oxide
About Zinc oxideZinc compound, A sunscreen,antipruritic.Mechanism of Action of Zinc oxideIt works by providing a skin barrier and helps in healing and prevent skin irritation. It acts as a sunscreen which absorbs incident solar radiation in the UVA ranges and reduces its transmission to the skin.Pharmacokinets of Zinc oxideN/AOnset of Action for Zinc oxideN/ADuration of Action for Zinc oxideN/AHalf Life of Zinc oxideN/ASide Effects of Zinc oxide1.Rash
2.Hives
3.Difficulty breathing
4.Tightness in the chest
5.Swelling of the mouth, face, lips, or tongue
6.Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
7.Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.
Contra-indications of Zinc oxide1.Hypersensitivity to Zinc oxide
2.Allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax. Special Precautions while taking Zinc oxide1.Allergic to Zinc preparations
2.Zinc oxide topical will not treat a bacterial or fungal infection
3.Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper
4.Avoid getting this medication in your mouth or eyes
5.Do not use zinc oxide topical on deep skin wounds or severe burns
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Zinc oxide1.To prevent minor skin irritations such as burns, cuts, poison ivy, poison oak, poison sumac, and diaper rash.
2.As sunscreen
3.Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
4.Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements
Interactions for Zinc oxideN/ATypical Dosage for Zinc oxideApply the medicament to the affected part 2 times daily.Schedule of Zinc oxideN/AStorage Requirements for Zinc oxideStore at 15 - 30 degree C.Protect from heat,light and moisture.Keep out of the reach of children.Effects of Missed Dosage of Zinc oxideApply the missed dose as soon as noticed.Effects of Overdose of Zinc oxideGive supportive measures and symptomatic treatment.Home Delivery for Clotrimazole + Menthol + Ichthammol + Zinc oxide in Your City
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Clotrimazole + Menthol + Ichthammol + Zinc oxide is a generic medicine name and there are several brands available for it. Some of the brands for clotrimazole + menthol + ichthammol + zinc oxide might be better known than clotrimazole + menthol + ichthammol + zinc oxide itself. If the pharmacy that's willing to deliver medicines to your home doesn't have clotrimazole + menthol + ichthammol + zinc oxide in stock, you can ask for one of the branded alternatives for clotrimazole + menthol + ichthammol + zinc oxide.