Atorvastatin + Vitamin D 3 Pharmacology

Atorvastatin + Vitamin D 3

About Atorvastatin + Vitamin D 3
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Mechanism of Action of Atorvastatin + Vitamin D 3
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Pharmacokinets of Atorvastatin + Vitamin D 3
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Onset of Action for Atorvastatin + Vitamin D 3
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Duration of Action for Atorvastatin + Vitamin D 3
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Half Life of Atorvastatin + Vitamin D 3
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Side Effects of Atorvastatin + Vitamin D 3
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Contra-indications of Atorvastatin + Vitamin D 3
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Special Precautions while taking Atorvastatin + Vitamin D 3
N/A
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Atorvastatin + Vitamin D 3
Elevated cholesterol conditions.
Interactions for Atorvastatin + Vitamin D 3
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Typical Dosage for Atorvastatin + Vitamin D 3
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Schedule of Atorvastatin + Vitamin D 3
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Storage Requirements for Atorvastatin + Vitamin D 3
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Effects of Missed Dosage of Atorvastatin + Vitamin D 3
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Effects of Overdose of Atorvastatin + Vitamin D 3
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Atorvastatin

About Atorvastatin
HMG-CoA Reductase Inhibitor, statins, Antilipemic agent.
Mechanism of Action of Atorvastatin
It is a more potent statin which competitively inhibits the conversion of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA) to mevalonate. The drug exerts it`s action by specific inhibition of enzyme; 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG CoA reductase) and reduces cholesterol synthesis up to 50% at therapeutic doses. This results in compensatory increase in low density lipoprotein (LDL) receptor expression in liver which ultimately leads to increased receptor mediated uptake and catabolism of intermediate density lipoprotein(IDL) and low density lipoprotein (LDL). It causes dose dependent lowering of LDL cholesterol and reduces hepatic synthesis of very low density lipoprotein (VLDL) and lowers plasma triglyceride levels. It also increases high density lipoprotein (HDL) levels. It also exerts antioxidant property.
Pharmacokinets of Atorvastatin
Absorption: Readily absorbed orally, Distribution: Widely distributed in a highly protein bound form, Metabolism: Metabolized in liver in to active metabolite, Excretion: Excreted mainly through bile.
Onset of Action for Atorvastatin
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Duration of Action for Atorvastatin
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Half Life of Atorvastatin
18 to 24 hours
Side Effects of Atorvastatin
1.Headache
2.Dizziness
3.Insomnia
4.Alopecia
5.Anorexia
6.Abdominal discomfort
7.Heart burn
8.Abdominal pain
9.Nausea
10.Dyspepsia
11.Flatulence
12.Constipation
13.Abnormal liver function tests
14.Rash
15.Pruritus
16.Fatigue
17.Myositis
18.Chest pain
19.Impotence
20.Myopathy
21.Upper respiratory tract infections

Contra-indications of Atorvastatin
1.Hypersensitivity to the drug
2.Active liver diseases
3.Persistent elevation of serum transaminase levels
Special Precautions while taking Atorvastatin

1.Monitor hepatic function tests and lipid levels before and periodically during therapy and stop drug if there is marked elevation of creatinine phosphokinase level
2.History of liver diseases
3.Alcoholics
4.In severe adverse effects and fever


Pregnancy Related Information
Contraindicated
Old Age Related Information
May be used
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Below 9years: Contraindicated
Indications for Atorvastatin
1.Hypercholesterolemia
2.Combined hyperlipidaemia
Interactions for Atorvastatin
N/A
Typical Dosage for Atorvastatin
Oral:
Starts with 10mg once daily; Increased if required based on patients response.
Maximum dose: 80mg
Schedule of Atorvastatin
H
Storage Requirements for Atorvastatin
Store at room temperature at a range of 15 to 25 degree C.
Effects of Missed Dosage of Atorvastatin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Atorvastatin
Provide supportive care and symptomatic treatment.

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Special Precautions while taking
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Home Delivery for Atorvastatin + Vitamin D 3 in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including atorvastatin + vitamin d 3.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for atorvastatin + vitamin d 3 and other medicines and health products. Home delivery services for atorvastatin + vitamin d 3 may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take atorvastatin + vitamin d 3 only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for atorvastatin + vitamin d 3 before they complete the sale. You can get this information while placing the order for atorvastatin + vitamin d 3 with the pharmacy.

Atorvastatin + Vitamin D 3 is a generic medicine name and there are several brands available for it. Some of the brands for atorvastatin + vitamin d 3 might be better known than atorvastatin + vitamin d 3 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have atorvastatin + vitamin d 3 in stock, you can ask for one of the branded alternatives for atorvastatin + vitamin d 3.