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- Pharmacology For Benfotiamine + Mecobalamin + Alpha Lipoic Acid + Chromium
Benfotiamine + Mecobalamin + Alpha Lipoic Acid + Chromium Pharmacology
Benfotiamine + Mecobalamin + Alpha Lipoic Acid + Chromium
About Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AMechanism of Action of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/APharmacokinets of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AOnset of Action for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/ADuration of Action for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AHalf Life of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/ASide Effects of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AContra-indications of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/ASpecial Precautions while taking Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumNutritional supplement Interactions for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/ATypical Dosage for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/ASchedule of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AStorage Requirements for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AEffects of Missed Dosage of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/AEffects of Overdose of Benfotiamine + Mecobalamin + Alpha Lipoic Acid + ChromiumN/ABenfotiamine
About BenfotiamineSynthetic S-acyl derivative of thiamine (vitamine B1), Antioxidant ,anti-AGE(Advanced glycation end product) supplement, Treating Diabetic Complications.Mechanism of Action of BenfotiamineN/APharmacokinets of BenfotiamineN/AOnset of Action for BenfotiamineN/ADuration of Action for BenfotiamineN/AHalf Life of BenfotiamineN/ASide Effects of BenfotiamineN/AContra-indications of BenfotiamineN/ASpecial Precautions while taking BenfotiamineN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Benfotiamine1.Management of diabetic neuropathy, diabetic nephropathy and diabetic retinopathy
2.Beri Beri
3.Wenicke-korsakoff syndrome
Interactions for BenfotiamineN/ATypical Dosage for BenfotiamineN/ASchedule of BenfotiamineN/AStorage Requirements for BenfotiamineN/AEffects of Missed Dosage of BenfotiamineN/AEffects of Overdose of BenfotiamineN/AMecobalamin
About MecobalaminWater soluble, Form of Vitamin B12Mechanism of Action of MecobalaminMecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.Pharmacokinets of MecobalaminAbsorption: Absorbed after oral, sublingual, injection
Excretion: Excretion via urine
Onset of Action for MecobalaminN/ADuration of Action for MecobalaminN/AHalf Life of MecobalaminN/ASide Effects of Mecobalamin1.Oral: Anorexia, nausea, vomiting and diarrhea
2.Parenteral: Rash, headache, hot sensation, diaphoresis and pain/induration at IM inj site
Contra-indications of MecobalaminN/ASpecial Precautions while taking MecobalaminN/APregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Mecobalamin1.Peripheral neuropathies
2.Megaloblastic anaemia
Interactions for Mecobalamin1.Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicines
2.Reduced serum concentrations with oral contraceptives
3.Reduced effects in anaemia with parenteral chloramphenicol
Typical Dosage for MecobalaminPeripheral neuropathies
Oral: Adult: 1500 mcg/day in 3 divided doses
Parenteral: 500 mcg daily IM/IV 3 times/wk
Megaloblastic anaemia caused by vitamin B12 deficiency
Parenteral: Adult: 500 mcg daily IM/IV 3 times/wk. Maintenance dose: After about 2 mth of therapy, reduce dose to single admin of 500 mcg every 1-3 mth.Schedule of MecobalaminN/AStorage Requirements for MecobalaminOral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.
Effects of Missed Dosage of MecobalaminN/AEffects of Overdose of MecobalaminN/AAbout N/AMechanism of Action of N/APharmacokinets of N/AOnset of Action for N/ADuration of Action for N/AHalf Life of N/ASide Effects of N/AContra-indications of N/ASpecial Precautions while taking N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for N/AInteractions for N/ATypical Dosage for N/ASchedule of N/AStorage Requirements for N/AEffects of Missed Dosage of N/AEffects of Overdose of N/AChromium
About ChromiumChromium is by far the most pivotal nutrient involved in sugar metabolism. Trivalent chromium is a part of glucose tolerance factor, an essential activator of insulin mediated reactions. Chromium improves insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increases in insulin sensitivity. Thus it helps to maintain normal glucose metabolism and peripheral nerve function. A number of clinical studies have been conducted which show that chromium is an effective therapy for both Type I and Type II diabetes. Except for supplementation, there is no good way to rebuild the body?s stockpile of chromium.
Deficiency symptoms: Impaired glucose tolerance, peripheral neuropathy, ataxia, confusion.
Over dosage symptoms: In normal therapeutic doses side effects have not been reported except occasional insomnia. In the event of over dosage - nausea, vomiting, GI ulcers, renal/hepatic damage, convulsion, coma may occur.
Mechanism of Action of ChromiumChromium picolinate acts by influencing carbohydrate metabolism. It stimulates Insulin mediated reactions and improves glucose tolerance. Chromium picolinate helps to improve; insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increase in insulin sensitivity. Thus it maintains normal glucose metabolism and peripheral nerve functions. It improves carbohydrate metabolism, increases energy and helps to control diabetes. It also helps to control weight.Pharmacokinets of ChromiumAbsorption: Well absorbed orally, Distribution: Widely distributed in the body in especially in to liver, kidney, bone, and spleen; normal plasma level is 1 to 5mcg/l. Excretion: Excreted mainly through urine.Onset of Action for ChromiumN/ADuration of Action for ChromiumN/AHalf Life of ChromiumN/ASide Effects of ChromiumN/AContra-indications of Chromium1. Hypersensitivity to the drug.Special Precautions while taking Chromium1. Prolonged therapy with the drug
2.Hypoglycaemia
3.In patients with Type II diabetes mellitus use of chromium picolinate is only under the direct medical supervision
4.Renal impairment
5.Hepatic impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Chromium1.Type I diabetes mellitus
2.Type II diabetes mellitus
3.Obesity.
Interactions for ChromiumN/ATypical Dosage for Chromium Oral: 200 mcg daily; increases up to 1mg daily if required.Schedule of ChromiumN/AStorage Requirements for ChromiumStore in a well closed container at a cool dry place.Effects of Missed Dosage of ChromiumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ChromiumGive supportive measures and symptomatic treatment.Home Delivery for Benfotiamine + Mecobalamin + Alpha Lipoic Acid + Chromium in Your City
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Benfotiamine + Mecobalamin + Alpha Lipoic Acid + Chromium is a generic medicine name and there are several brands available for it. Some of the brands for benfotiamine + mecobalamin + alpha lipoic acid + chromium might be better known than benfotiamine + mecobalamin + alpha lipoic acid + chromium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have benfotiamine + mecobalamin + alpha lipoic acid + chromium in stock, you can ask for one of the branded alternatives for benfotiamine + mecobalamin + alpha lipoic acid + chromium.