- Medicine India
- Generic Medicines
- H
- Pharmacology For Halobetasol Propionate + Salicylic Acid
Halobetasol Propionate + Salicylic Acid Pharmacology
Halobetasol Propionate + Salicylic Acid
About Halobetasol Propionate + Salicylic AcidN/AMechanism of Action of Halobetasol Propionate + Salicylic AcidN/APharmacokinets of Halobetasol Propionate + Salicylic AcidN/AOnset of Action for Halobetasol Propionate + Salicylic AcidN/ADuration of Action for Halobetasol Propionate + Salicylic AcidN/AHalf Life of Halobetasol Propionate + Salicylic AcidN/ASide Effects of Halobetasol Propionate + Salicylic AcidN/AContra-indications of Halobetasol Propionate + Salicylic AcidN/ASpecial Precautions while taking Halobetasol Propionate + Salicylic AcidN/APregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Halobetasol Propionate + Salicylic Acid1.Psoriasis
2.Eczema
3.Dermatitis
4.Lichen simplex
5.Lichen planus
Interactions for Halobetasol Propionate + Salicylic AcidN/ATypical Dosage for Halobetasol Propionate + Salicylic AcidN/ASchedule of Halobetasol Propionate + Salicylic AcidN/AStorage Requirements for Halobetasol Propionate + Salicylic AcidN/AEffects of Missed Dosage of Halobetasol Propionate + Salicylic AcidN/AEffects of Overdose of Halobetasol Propionate + Salicylic AcidN/AHalobetasol propionate
About Halobetasol propionateTopical primarily synthetic Corticosteroid, Antiinflammatory and antipruritic.Mechanism of Action of Halobetasol propionateHalobetasol propionate is a synthetic corticosteroid for topical dermatological use. The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows its migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Halobetasol propionateAbsorption: It is absorbed after topical application.Onset of Action for Halobetasol propionateN/ADuration of Action for Halobetasol propionateN/AHalf Life of Halobetasol propionateN/ASide Effects of Halobetasol propionate1.Burning
2.Stinging
3.Itching
4.Redness
5.Blistering
6.Peeling
Contra-indications of Halobetasol propionate1.Hypersensitivity to Halobetasol propionate
2.Occlusive dressings
Special Precautions while taking Halobetasol propionate1.Avoid contact with eyes
2.For external use only
3.Prolonged use
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: contraindicatedIndications for Halobetasol propionate1.Eczema
2.Psoriasis
3.Dermatitis
4. Rashes
5.Insect bites
6.Poison ivy
7.Inflammation of the skin
Interactions for Halobetasol propionateN/ATypical Dosage for Halobetasol propionateApply to the affected area 2 - 4 times a day. Halobetasol should not be used for longer than 2 weeksSchedule of Halobetasol propionateN/AStorage Requirements for Halobetasol propionateStore at room temperature in a well closed; light resistant container. Protect from excess heat and moisture. Keep out of reach of children.Effects of Missed Dosage of Halobetasol propionateApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Halobetasol propionateProvide symptomatic treatment and supportive measures.Salicylic Acid
About Salicylic AcidA beta hydroxy acid, Keratolytic, Topical Skin Product(Anti Acne).Mechanism of Action of Salicylic AcidIt is a keratolytic agent. It encourages exfoliation of the skin and opening up of the plugged follicles, which helps re-establish the normal skin- cell replacement cycle. For milder acne, salicylic acid helps unclog pores to resolve and prevent lesions.Pharmacokinets of Salicylic AcidN/AOnset of Action for Salicylic AcidN/ADuration of Action for Salicylic AcidN/AHalf Life of Salicylic AcidN/ASide Effects of Salicylic Acid1.Allergic reaction
2.Hives
3.Difficulty breathing
4.Swelling of your face, lips, tongue, or throat.
Contra-indications of Salicylic Acid1.Hypersensitivity to Salicylic acidSpecial Precautions while taking Salicylic Acid1.Avoid contact with eyes, mouth, or nose.
2.Like many other topical acne treatments, salicylic acid must be used continuously, even after acne lesions have.Pregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Salicylic Acid1.Treats skin irritation and inflammation caused by burns, insect bites, fungal infections, and eczema.Interactions for Salicylic AcidN/ATypical Dosage for Salicylic AcidUse this medication twice daily Schedule of Salicylic AcidN/AStorage Requirements for Salicylic AcidStore in a cool dry place. Protect from heat and light. Keep out of the reach of childrenEffects of Missed Dosage of Salicylic AcidApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Salicylic AcidGive supportive measures and symptomatic treatment.Home Delivery for Halobetasol Propionate + Salicylic Acid in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including halobetasol propionate + salicylic acid.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for halobetasol propionate + salicylic acid and other medicines and health products. Home delivery services for halobetasol propionate + salicylic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take halobetasol propionate + salicylic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for halobetasol propionate + salicylic acid before they complete the sale. You can get this information while placing the order for halobetasol propionate + salicylic acid with the pharmacy.
Halobetasol Propionate + Salicylic Acid is a generic medicine name and there are several brands available for it. Some of the brands for halobetasol propionate + salicylic acid might be better known than halobetasol propionate + salicylic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have halobetasol propionate + salicylic acid in stock, you can ask for one of the branded alternatives for halobetasol propionate + salicylic acid.