Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine Pharmacology

Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine

About Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Mechanism of Action of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Pharmacokinets of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Onset of Action for Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Duration of Action for Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Half Life of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Side Effects of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Contra-indications of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Special Precautions while taking Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
1.Peptic Ulcer Disease
2.GI Bleeding, Prophylaxis
3.For stomach upset, heartburn, and acid indigestion
4.To relieves bloating, pressure and discomfort commonly referred as gas
5.Reflux oesophagotis
Interactions for Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Typical Dosage for Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Schedule of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Storage Requirements for Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Effects of Missed Dosage of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Effects of Overdose of Magnesium Hydroxide + Aluminium Hydroxide + Simethicone + Sodium Alginate + Oxetacaine
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Magnesium Hydroxide

About Magnesium Hydroxide
Mineral, Magnesium compound, Antacid and laxative.
Mechanism of Action of Magnesium Hydroxide
It neutralize the gastric acid (where the hydroxide ions from the Mg(OH)2 combine with acidic H+ ions produced in the form of hydrochloric acid by parietal cells in the stomach). This relieves the hyperacidity problems in the stomach.
Pharmacokinets of Magnesium Hydroxide
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Onset of Action for Magnesium Hydroxide
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Duration of Action for Magnesium Hydroxide
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Half Life of Magnesium Hydroxide
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Side Effects of Magnesium Hydroxide
1. Stomach cramps
2. Upset stomach
3. Vomiting
4. Diarrhea
5. Black/tarry stools
6. Rectal bleeding.
7. Constipation
8. Loss of appetite
9. Unusual tiredness
10. Muscle weakness
11. Hypermagnesaemia
12. Renal failure
Contra-indications of Magnesium Hydroxide
1. Hypersensitivity to the drug
2. Kidney disease
3. Stomach/abdominal pain
4. Nausea
5. Vomiting
Special Precautions while taking Magnesium Hydroxide
1. Colostomy
2. Dehydration
3. Diarrhea
4. Intestinal problems like colitis
5.Do not take any other medication within 1 to 2 hours of taking this medication.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Less than 6 Years : Contraindicated
Indications for Magnesium Hydroxide
1. Constipation
2. Peptic ulcer
3. Hiatal hernia
Interactions for Magnesium Hydroxide
N/A
Typical Dosage for Magnesium Hydroxide
Oral-
Adult-
Antacid:
Tab-500mg to 1.5g daily.
Liquid-5-15ml daily.
Laxative:
Tab-2.4-4.8g daily.
Liquid -30-60ml daily.
Schedule of Magnesium Hydroxide
N/A
Storage Requirements for Magnesium Hydroxide
Store it at room temperature (15-30 degree C) and away from excess heat and moisture.
Effects of Missed Dosage of Magnesium Hydroxide
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Magnesium Hydroxide
Give symptomatic and supportive treatment.

Aluminium Hydroxide

About Aluminium Hydroxide
Antacid,Antidote,Protectant( Topical), In hyperacidity; hyperphosphatemia.
Mechanism of Action of Aluminium Hydroxide
It neutralizes and reduces stomach acid relieving heartburn (acid reflux, GERD) and indigestion. This results increased pH and reduce the pepsin activity. It also binds to the phosphate in the gut and form a nonsoluble nonabsorbable aluminium phosphate complex.
Pharmacokinets of Aluminium Hydroxide
Absorption- Poorly absorbed.Excretion- Excreted through feces and breast milk
Onset of Action for Aluminium Hydroxide
N/A
Duration of Action for Aluminium Hydroxide
20 to 180minutes
Half Life of Aluminium Hydroxide
N/A
Side Effects of Aluminium Hydroxide
1. Loss of appetite
2. Constipation
3. Hypophosphatemia
4. Osteomalacia
5. Confusion
6. Unusual tiredness or discomfort
7. Muscle weakness
8. Encephalopathy
Contra-indications of Aluminium Hydroxide
1. Hypersensitivity to the drug
2. Renal failure
3. Hypertension
4. Heart disease
5. Kidney disease
6. Gastrointestinal bleeding.
Special Precautions while taking Aluminium Hydroxide
1. Stomach problems
2. Allergies
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
May be used
Indications for Aluminium Hydroxide
1. Gastric hyperacidity
2. Ulcers
3. Digestive disorders
4. Hyperphosphatemia
5. Oesophagitis
6. Hiatal hernia
7. Gastritis
Interactions for Aluminium Hydroxide
N/A
Typical Dosage for Aluminium Hydroxide
Oral-
Acidity and Hyperphosphatemia -
Adult-
500-1500mg tablet or capsule 1 hr after meals and at bed time
5 to 30 ml suspension1 hr after meals and at bed time as needed
Schedule of Aluminium Hydroxide
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Storage Requirements for Aluminium Hydroxide
Store it at room temperature and away from excess heat and moisture. Refrigerate the suspension. Do not freeze.
Effects of Missed Dosage of Aluminium Hydroxide
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Aluminium Hydroxide
Give symptomatic and supportive treatment

Simethicone

About Simethicone
Oral anti-foaming agent, Silicones, Antiflatulent.
Mechanism of Action of Simethicone
This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.
Pharmacokinets of Simethicone
Excretion- Excreted through feces.
Onset of Action for Simethicone
N/A
Duration of Action for Simethicone
N/A
Half Life of Simethicone
N/A
Side Effects of Simethicone
1. Bloating
2. Constipation
3. Diarrhea
4. Gas
5. Heartburn
Contra-indications of Simethicone
1. Hypersensitivity to the drug
2. Liver disease
3. Kidney disease
4. Serious illness
Special Precautions while taking Simethicone
1.Swallow the tablets and capsules with a full glass of water.
2.Chew the chewable tablets thoroughly before swallowing.
3.Shake the drops well before using them.
4.To make administration easier, the drops can be mixed with 30 ml (2 tablespoons) of water or another liquid.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Simethicone
1. Abdominal pain which is due to excessive gas in the digestive tract
2. Before gastroscopy or radiography of the bowel
Interactions for Simethicone
N/A
Typical Dosage for Simethicone
Oral-
Adults and teenagers-
60 -125mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Chewable tablets:
Adults and teenagers-
40 -125 mg four times a day, after meals and at bedtime or 150 mg three times a day, after meals. Not more than 500 mg should be taken in twenty-four hours.
Suspension:
Adults and teenagers-
40 -95 mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Schedule of Simethicone
N/A
Storage Requirements for Simethicone
Stored at room temperature (15-30?C) away from moisture and heat.
Effects of Missed Dosage of Simethicone
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Simethicone
Give symptomatic and supportive treatment.

Sodium Alginate

About Sodium Alginate
A hydrophilic colloidal polysaccharide, Added to an antacid as protective agent.
Mechanism of Action of Sodium Alginate
Sodium alginate is the sodium salt of alginic acid.Alginic acid powder swells when wetted with water. This may prevent reflux of acid into the esophagus by keeping the gastric contents in place and reduce the likelihood of reflux irritating the lining of the esophagus. The sodium calcium alginate fibres in haemostatic wound dressings absorbed by body fluids, as the calcium in the fiber is exchanged for sodium from the body fluids mixed salts of sodium and calcium alginate, and processed into non-woven fabric that is used in wound dressings. It binds with heavy metals and radioactive substances to its own molecules. It cannot be broken down by bile or saliva to be absorbed and secreted from the body together with heavy metals and radioactive substances.
Pharmacokinets of Sodium Alginate
When ingested, Sodium alginate releases alginic acid and almost all of the alginic acid remains undigested and is excreted either unchanged or as an alginate.
Onset of Action for Sodium Alginate
N/A
Duration of Action for Sodium Alginate
30 to 60 minutes
Half Life of Sodium Alginate
N/A
Side Effects of Sodium Alginate
1. Abdominal distension
2. Flatulence
3. Chalky taste in your mouth
4. Constipation
5. Diarrhea
6. Nausea
7. Vomiting.
Contra-indications of Sodium Alginate
1. Hypersensitivity to the drug
2. Heart failure.
3. Renal failure.
Special Precautions while taking Sodium Alginate
1.Allergies to medicines, foods, or other substances
2.Alzheimer disease
3.Appendicitis
4.Diarrhoea
5.Stomach blockage
6.Kidney problems
7.Liver problems
8.Ileostomy
9.Congestive heart failure
10.Decreased urination
11.Fluid retention
12.Rectal bleeding of unknown cause
13.Recently had stomach bleeding
14.Patient on low salt diet
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Sodium Alginate
1. Heartburn (including heartburn of pregnancy)
2. Dyspepsia
3. Reflux oesophagitis
4. Hiatus hernia.
5. Protect inflamed areas near the entrance to the stomach (Sodium alginate)
Interactions for Sodium Alginate
N/A
Typical Dosage for Sodium Alginate
Take the drug as directed by the physician.
Schedule of Sodium Alginate
N/A
Storage Requirements for Sodium Alginate
Store below 25?C in a tightly closed container.
Effects of Missed Dosage of Sodium Alginate
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sodium Alginate
Give symptomatic and supportive treatment.

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