- Medicine India
- Generic Medicines
- F
- Pharmacology For Folic Acid + Iodine
Folic Acid + Iodine Pharmacology
Folic Acid + Iodine
About Folic Acid + IodineN/AMechanism of Action of Folic Acid + IodineN/APharmacokinets of Folic Acid + IodineN/AOnset of Action for Folic Acid + IodineN/ADuration of Action for Folic Acid + IodineN/AHalf Life of Folic Acid + IodineN/ASide Effects of Folic Acid + IodineN/AContra-indications of Folic Acid + IodineN/ASpecial Precautions while taking Folic Acid + IodineN/APregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Folic Acid + IodineMaternal nutritional supplement during pre conception & pregnancyInteractions for Folic Acid + IodineN/ATypical Dosage for Folic Acid + IodineAs directed by the PhysicianSchedule of Folic Acid + IodineN/AStorage Requirements for Folic Acid + IodineN/AEffects of Missed Dosage of Folic Acid + IodineN/AEffects of Overdose of Folic Acid + IodineN/AFolic Acid
About Folic AcidDietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.Mechanism of Action of Folic AcidFolic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.Pharmacokinets of Folic AcidAbsorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic AcidOral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic AcidOral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic AcidN/ASide Effects of Folic AcidN/AContra-indications of Folic AcidN/ASpecial Precautions while taking Folic Acid1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Folic Acid1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic AcidOral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic AcidC1 (Oral)
C (Parenteral)
Storage Requirements for Folic AcidStore at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.Effects of Missed Dosage of Folic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Folic AcidRelatively non toxic. Provide symptomatic treatment and supportive measures.Iodine
About IodineEssential trace element, fastest acting thyroid inhibitor, Antithyroid agent.Mechanism of Action of IodineIt is the fastest acting thyroid inhibitor which inhibits hormone release. It reduced to iodide response to both iodine and iodides are identical. Endocytosis of colloid and proteolysis of thyroglobulin comes to a halt. It has a direct action on thyroid cells and also attenuate TSH and cyclic AMP induced thyroid stimulation. Excess iodide inhibits it`s on transport in thyroid cells and alter the redox potential of cells; thus interfering with iodination and reduces T3 or T4 synthesis. The gland if enlarged; shrinks, becomes firm and less vascular. The thyroid status returns to normal at a faster rate.Pharmacokinets of IodineAbsorption: Well absorbed orally.
Distribution: Widely distributed in the body and also crosses the placenta.
Onset of Action for IodineN/ADuration of Action for IodineN/AHalf Life of IodineN/ASide Effects of Iodine1. Fever
2. Angioedema
3. Swelling of lips and eyelids
4. Arthralgia
5. Thrombocytopenia
6. Salivation
7. Sneezing
8. Lymphadenopathy
9. Petechial haemorrhage.
10. Burning sensation in mouth
11. Headache
12. Rashes
13. Flaring of acne
Contra-indications of Iodine1. Hypersensitivity to the drugSpecial Precautions while taking Iodine1. Long term therapy with high dosePregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Iodine1. Hyperthyroidism
2. Hypothyroidism
3. Prior to thyroidectomy
4. Prophylaxis of endemic goiter
Interactions for IodineN/ATypical Dosage for IodineOral: 5 to 10ml in water 8th hourly.Schedule of IodineHStorage Requirements for IodineStore in a well closed container and protects from light.Effects of Missed Dosage of IodineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of IodineProvide symptomatic treatment and supportive measures.
Home Delivery for Folic Acid + Iodine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including folic acid + iodine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for folic acid + iodine and other medicines and health products. Home delivery services for folic acid + iodine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take folic acid + iodine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for folic acid + iodine before they complete the sale. You can get this information while placing the order for folic acid + iodine with the pharmacy.
Folic Acid + Iodine is a generic medicine name and there are several brands available for it. Some of the brands for folic acid + iodine might be better known than folic acid + iodine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have folic acid + iodine in stock, you can ask for one of the branded alternatives for folic acid + iodine.