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- Pharmacology For Amoxycillin + Carbocysteine
Amoxycillin + Carbocysteine Pharmacology
Amoxycillin + Carbocysteine
About Amoxycillin + CarbocysteineN/AMechanism of Action of Amoxycillin + CarbocysteineN/APharmacokinets of Amoxycillin + CarbocysteineN/AOnset of Action for Amoxycillin + CarbocysteineN/ADuration of Action for Amoxycillin + CarbocysteineN/AHalf Life of Amoxycillin + CarbocysteineN/ASide Effects of Amoxycillin + CarbocysteineN/AContra-indications of Amoxycillin + CarbocysteineN/ASpecial Precautions while taking Amoxycillin + CarbocysteineN/APregnancy Related InformationContraindicated; Carbocysteine is contraindicated in pregnancy so the combination generic cannot be used in pregnancyOld Age Related InformationN/ABreast Feeding Related InformationContraindicated; Carbocysteine is contraindicated in lactation so the combination generic cannot be used in breast feeding.Children Related InformationN/AIndications for Amoxycillin + CarbocysteineChronic bronchitis with excessive viscous mucusInteractions for Amoxycillin + CarbocysteineN/ATypical Dosage for Amoxycillin + CarbocysteineAdult: 1 tablet to be taken 3 times daily for 5 days.
Amoxicillin 500 mg + Carbocysteine 150 mg
Children: 20 mg/kg body wt. In 3 divided doses
Schedule of Amoxycillin + CarbocysteineN/AStorage Requirements for Amoxycillin + CarbocysteineN/AEffects of Missed Dosage of Amoxycillin + CarbocysteineN/AEffects of Overdose of Amoxycillin + CarbocysteineN/AAmoxycillin
About AmoxycillinSemisynthetic Broad spectrum beta-lactam antibiotic, An aminopenicillin Derivative.Mechanism of Action of AmoxycillinAmoxycillin is a bactericidal drug. It is a Beta lactum antibiotic. It binds to the Penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis. Amoxycillin is active against gram positive and gram negative bacteria except penicillinase producing once.Pharmacokinets of AmoxycillinAbsorption .It is well absorbed after oral administration. Distribution: It is very widely distributed in the body .Metabolism: In significant metabolism. Excretion: It is excreted mainly through urine and small amount excreted
in breast milk
Onset of Action for Amoxycillin60 -120 minutesDuration of Action for Amoxycillin6-8 hoursHalf Life of Amoxycillin60 minutesSide Effects of Amoxycillin1.Aaphylaxis
2. Vomiting
3.Diarrhoea
4 Nausea
5.Rash
6.Urticaria
7.Thrombocytopenia
8.Nephritis
9.Seizure
10.Super infections.
Contra-indications of AmoxycillinHypersensitivity to Amoxicillin and other Penicillins.Special Precautions while taking Amoxycillin1.Mononucleosis
2.Lymphatic leukaemia
3.HIV infections
4.Hepatic impairment
5.Renal impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Amoxycillin1Urinary tract infections
2.Gonorrhoea
3 Meningitis
4.SABE
5.Respiratory tract infections
6.Septicemia
7.Soft tissue infections
8.Otitis media
9.Sinusitis
10.Tetanus
11.Biliarytract infections
12.Bronchitis
13.Salmonellosis
14.Typhoid
15.Gastroenteritis
16.Chlamydia infection
17.Paratyphoid fever
18.Dental infections
Interactions for AmoxycillinOral contraceptives: Efficacy reduced, may cause breakthrough bleeding or pregnancy.
Erythromycin, Tetracycline: Reduce efficacy.Typical Dosage for AmoxycillinADULT: 250 - 500 mg three to four times daily.
In severe infections dose can be increased to 3 - 6 g daily depending on the severity of infection.
CHILDREN:125 - 250 mg three to four times a day depending on the severity of infection.
Schedule of AmoxycillinHStorage Requirements for AmoxycillinIt should store at temperature below 25 degree C. Keep away from moisture and heat. Keep out of the reach of children.Effects of Missed Dosage of AmoxycillinTake the dose as soon as noticed and if it is the time to the next dose then skip the missed doseEffects of Overdose of AmoxycillinGive supportive measures and symptomatic treatment. If the patient is conscious induce emesis or gastric lavage followed by charcoal administration. Haemodialysis can be done if needed.
Carbocysteine
About CarbocysteineMucoactive drug, : local anti-infective agents, expectorants.Mechanism of Action of CarbocysteineCarbocysteine is a mucolytic which liquefies the viscid sputum. It acts on the metabolism of mucus producing cells. It induces the production of mucus with increased sialomucin content. Sialomucin influences the rheological properties of mucus and also inhibits kinins and prevents bronchial inflammation and bronchospasm. It normalizes mucus viscosity and reduces goblet cell hyperplasia.Pharmacokinets of CarbocysteineAbsorption: Administered orally.Onset of Action for CarbocysteineN/ADuration of Action for CarbocysteineN/AHalf Life of CarbocysteineN/ASide Effects of Carbocysteine1. Gastrointestinal irritation
2. Rashes
3. Headache
4. Nausea
5. Diarrhoea
6. Dizziness
7. Palpitations
8. Heartburn
9. Gastrointestinal bleedingContra-indications of Carbocysteine1. Hypersensitivity to the drug
2. Peptic ulcerSpecial Precautions while taking CarbocysteineHistory of gastric or duodenal ulcer.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Carbocysteine1. Bronchitis
2. Broncheistasis
3. Bronchial obstruction
4. Asthma
5. Upper respiratory tract congestion
6. Sinusitis
7. Rhinopharyngitis
8. Adjunctive therapy in respiratory tract disorders with excessive viscous mucous in the absence of infectionInteractions for CarbocysteineN/ATypical Dosage for CarbocysteineAdults: 500 to 750mg thrice daily.
Children (5 to 12 years): 250mg thrice daily.
Children (2 to 5 years): 125mg two to four times daily as required.
Schedule of CarbocysteineHStorage Requirements for CarbocysteineStore at a temperature below 25 degree C. Protect from light. Keep out of reach of children.Effects of Missed Dosage of CarbocysteineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CarbocysteineProvide symptomatic treatment and supportive measures.Home Delivery for Amoxycillin + Carbocysteine in Your City
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Amoxycillin + Carbocysteine is a generic medicine name and there are several brands available for it. Some of the brands for amoxycillin + carbocysteine might be better known than amoxycillin + carbocysteine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have amoxycillin + carbocysteine in stock, you can ask for one of the branded alternatives for amoxycillin + carbocysteine.