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- Pharmacology For Diacerein + Glucosamine + Methyl Sulfonyl Methane
Diacerein + Glucosamine + Methyl Sulfonyl Methane Pharmacology
Diacerein + Glucosamine + Methyl Sulfonyl Methane
About Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AMechanism of Action of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/APharmacokinets of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AOnset of Action for Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/ADuration of Action for Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AHalf Life of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/ASide Effects of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AContra-indications of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/ASpecial Precautions while taking Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Diacerein + Glucosamine + Methyl Sulfonyl MethaneOsteoarthritisInteractions for Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/ATypical Dosage for Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/ASchedule of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AStorage Requirements for Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AEffects of Missed Dosage of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/AEffects of Overdose of Diacerein + Glucosamine + Methyl Sulfonyl MethaneN/ADiacerein
About DiacereinInterleukin-1 inhibitor, anthraquinones derivative, disease modifying anti-rheumatoid drug -NSAID, Anti osteoarthritic and cartilage-stimulating properties.Mechanism of Action of DiacereinDiacerein is an antirheumatic drug. It produces its action by inhibiting Interleukin-1. It is a disease modifying anti-rheumatoid drug used in the treatment of Osteoarthritis and chronic inflammatory arthritis.
Diacerein is a slow-acting, symptom-modifying and disease-structure modifying drug for osteoarthritis. In arthritis the cartilage that protects the ends of the bones breaks down and causes pain and swelling. Diacerein may slow down the breakdown of cartilage and relieve pain and swelling.
Pharmacokinets of DiacereinAbsorption: It is orally absorbed. Distribution: It is distributed mainly in protein bound form. Metabolism: It undergoes metabolism in the liver. Excretion: It is excreted mainly through urine.Onset of Action for DiacereinN/ADuration of Action for DiacereinN/AHalf Life of Diacerein4 - 5 hoursSide Effects of Diacerein1.Diarrhoea
2.Heartburn
3.Soft stools
4.Stomach pain
5.Frequent bowel movements
Contra-indications of DiacereinHypersensitivity to DiacereinSpecial Precautions while taking Diacerein1.Hepatic impairment
2.Renal impairment
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationNot recommendedIndications for DiacereinOsteoarthritisInteractions for DiacereinN/ATypical Dosage for DiacereinAdult: 100 mg / day in two divided doses. Schedule of DiacereinN/AStorage Requirements for DiacereinStored in cool airtight container. Keep out of the reach of children.Effects of Missed Dosage of DiacereinTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of DiacereinGive supportive measures and symptomatic treatmentGlucosamine
About GlucosamineAmino sugar,Monosaccharide derivative, Anti-inflammatory,Antiarthritic.Mechanism of Action of GlucosamineIt stimulates cartilage cells to produce glucosaminoglycans and proteoglycans which are the building blocks of cartilage. This stops the progression of OA (osteoarthritis) and possibly reverses the process. It also has anti-inflammatory properties by its inhibition of proteolytic enzymes.Pharmacokinets of GlucosamineAbsorption- Well absorbed after oral administration
Distribution- Widely distributed into joint tissues
Excretion - Excreted through urine
Onset of Action for GlucosamineN/ADuration of Action for GlucosamineN/AHalf Life of GlucosamineN/ASide Effects of Glucosamine1. Epigastric pain
2. Tenderness
3. Heartburn
4. Diarrhoea
5. Nausea
6. Drowsiness
7. Headache
8. Insomnia
9. Vomiting
10. Constipation
11. Anorexia
12. Erythema
13. PruritisContra-indications of GlucosamineContraindicated in patients with hypersensitivity to the drugSpecial Precautions while taking Glucosamine1.Blood sugars carefully monitored because Glucosamine may increase insulin resistance
2.In normal and diabetic patients
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Glucosamine1. Osteo arthritis.
2. Rheumatoid arthritis
Interactions for GlucosamineN/ATypical Dosage for GlucosamineOral-
Adult:1200mg /day
Schedule of GlucosamineN/AStorage Requirements for GlucosamineStore in cool (<30 degree C) and dark placeEffects of Missed Dosage of GlucosamineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of GlucosamineGive symptomatic and supportive treatmentMethyl sulfonyl methane
About Methyl sulfonyl methaneN/AMechanism of Action of Methyl sulfonyl methaneMSM has been proven to have anti-inflammatory and antioxidant mechanisms in an in vitro study6 in which human neutrophils were artificially stimulated to produce oxidative compounds, including hydrogen peroxide, superoxide, and hypochlorous acid. After cell lines were treated with either DMSO or DMSO2, these free radical by-products were decreased.Pharmacokinets of Methyl sulfonyl methaneN/AOnset of Action for Methyl sulfonyl methaneN/ADuration of Action for Methyl sulfonyl methaneN/AHalf Life of Methyl sulfonyl methaneN/ASide Effects of Methyl sulfonyl methane1.Nausea
2.Diarrhea
3.Bloating
4.Fatigue
5.Headache
6.Insomnia
7.Itching or worsening of allergy symptoms.
Contra-indications of Methyl sulfonyl methaneN/ASpecial Precautions while taking Methyl sulfonyl methaneN/APregnancy Related InformationNot recommendedOld Age Related InformationN/ABreast Feeding Related InformationNot recommendedChildren Related InformationN/AIndications for Methyl sulfonyl methane1.To reduce pain and swelling of the joints caused by osteoarthritis.
2.Interstitial cystitis
Interactions for Methyl sulfonyl methaneN/ATypical Dosage for Methyl sulfonyl methaneOral: For osteoarthritis: 500 mg three times daily up to 3 grams twice daily.Schedule of Methyl sulfonyl methaneN/AStorage Requirements for Methyl sulfonyl methaneN/AEffects of Missed Dosage of Methyl sulfonyl methaneIf a dose is missed, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.Effects of Overdose of Methyl sulfonyl methaneIf over dosage is suspected,contact immediate medical attention.Home Delivery for Diacerein + Glucosamine + Methyl Sulfonyl Methane in Your City
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Diacerein + Glucosamine + Methyl Sulfonyl Methane is a generic medicine name and there are several brands available for it. Some of the brands for diacerein + glucosamine + methyl sulfonyl methane might be better known than diacerein + glucosamine + methyl sulfonyl methane itself. If the pharmacy that's willing to deliver medicines to your home doesn't have diacerein + glucosamine + methyl sulfonyl methane in stock, you can ask for one of the branded alternatives for diacerein + glucosamine + methyl sulfonyl methane.