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- Pharmacology For Bimatoprost + Timolol
Bimatoprost + Timolol Pharmacology
Bimatoprost + Timolol
About Bimatoprost + TimololN/AMechanism of Action of Bimatoprost + TimololN/APharmacokinets of Bimatoprost + TimololN/AOnset of Action for Bimatoprost + TimololN/ADuration of Action for Bimatoprost + TimololN/AHalf Life of Bimatoprost + TimololN/ASide Effects of Bimatoprost + TimololN/AContra-indications of Bimatoprost + TimololN/ASpecial Precautions while taking Bimatoprost + TimololN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationContraindicated
NEONATES:ContraindicatedIndications for Bimatoprost + TimololLowering intra-ocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT), including individuals uncontrolled on monotherapy with a beta-adrenergic receptor antagonist or prostaglandin analogue.Interactions for Bimatoprost + TimololN/ATypical Dosage for Bimatoprost + TimololN/ASchedule of Bimatoprost + TimololN/AStorage Requirements for Bimatoprost + TimololN/AEffects of Missed Dosage of Bimatoprost + TimololN/AEffects of Overdose of Bimatoprost + TimololN/ABimatoprost
About BimatoprostA synthetic structural analog of prostaglandin(a prostamide), Antiglaucomic Agents, ocular hypotensiveMechanism of Action of BimatoprostBimatoprost is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.Pharmacokinets of BimatoprostN/AOnset of Action for BimatoprostN/ADuration of Action for BimatoprostN/AHalf Life of BimatoprostN/ASide Effects of Bimatoprost1.Burning eyes
2.Cataract
3.Darkening of eyelashes
4.Darkening of the skin surrounding the eye
5.Dry eyes
6.Excessive hair growth
7.Eye irritation
8.Eye pain
9.Feeling of a foreign body in the eye
10.Growth of eyelashes
11.Headaches
12.Itchy eyes
13.Red eyelids
14.Respiratory infections
15.Swelling of the eyelids
16.Visual disturbances
17.Weakness
Contra-indications of BimatoprostHypersensitivity to BimatoprostSpecial Precautions while taking Bimatoprost1.Inflammation in the area of the iris (uveitis)
2.Swelling in the back of the eye (macular edema)
3.Kidney disease
4.Liver problems
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Bimatoprost1.Open angle GlaucomaInteractions for BimatoprostN/ATypical Dosage for BimatoprostThe recommended dose is 1 drop in the affected eye or eyes once daily in the evening. If wear contact lenses, remove them before using this. Wait 15 minutes before reinserting them. If you are using more than one type of eye drop, space the drugs 5 minutes apart.To avoid contamination and to reduce the risk of developing an eye infection, do not let the tip of the container touch the eye, face, or fingers.
Schedule of BimatoprostN/AStorage Requirements for BimatoprostStore in a cool dry area in a well closed container. Protects from moisture, light and direct heat.Effects of Missed Dosage of BimatoprostTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of BimatoprostProvide symptomatic treatment and supportive measures.Timolol
About TimololNonselective Beta Adrenergic,Blocker,Ophthalmic- Antiglaucoma,antimigraine.Mechanism of Action of TimololTimolol is a non selective beta blocker. It inhibits the beta receptors (?2) present in the eye such as in the ciliary body epithelium and blood vessels. This will leads to decreased aqueous production and reduced intraocular pressure. Aqueous humor production is activated by ? receptor mediated cyclic AMP phosphokinase pathway. Beta receptor blockers will decreases the intracellular cyclic AMP level and reduces intraocular pressure. Another mechanism is that Timolol decreases the ocular blood flow which decreases ultrafiltration responsible for aqueous production.Pharmacokinets of TimololAbsorption: Absorption after ophthalmic use is minimal.Onset of Action for Timolol30 minutesDuration of Action for Timolol12- 24 hoursHalf Life of TimololN/ASide Effects of Timolol1. Irritation
2. Burning
3. Bronchospasm
4. Blurred vision
5. Increased sensitivity of the eyes to light
6. Redness of eyes
7. Discoloration of the eyeball
8. Eye pain
Contra-indications of Timolol1. Hypersensitivity to Timolol
2. Bronchial asthma
3. Chronic obstructive pulmonary diseases
4. Sinus Bradycardia
5. Heart failure
6. Cardiogenic shock
7. AV block (2nd or 3rd degree)
Special Precautions while taking Timolol1. Chronic bronchitis
2. Emphysema
3. Diabetes mellitus
4. Hyperthyroidism
5. Myasthenia gravis
6. Closed angle glaucoma
7. Gradually withdraw the drug in patient with Thyrotoxicosis
8. Cerebrovascular insufficiency
9. Avid use of soft contact lenses.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationContraindicated
NEONATES: ContraindicatedIndications for Timolol1. Open angle glaucoma
2. Ocular hypertension
Interactions for TimololN/ATypical Dosage for TimololTimolol 0.25, and 0.5% eye drops are used.
Instill 1 drop in to the affected eye for 1 - 2 times daily.
Schedule of TimololHStorage Requirements for TimololStore in a cool dry place in a tightly closed container. Protect from heat and light. Keep out of the reach of children. Discard the drug 1 month after opening.Effects of Missed Dosage of TimololTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of TimololA topical ocular overdose of an ophthalmic product containing Timolol may be flushed from the eye with warm tap water.Home Delivery for Bimatoprost + Timolol in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for bimatoprost + timolol and other medicines and health products. Home delivery services for bimatoprost + timolol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take bimatoprost + timolol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for bimatoprost + timolol before they complete the sale. You can get this information while placing the order for bimatoprost + timolol with the pharmacy.
Bimatoprost + Timolol is a generic medicine name and there are several brands available for it. Some of the brands for bimatoprost + timolol might be better known than bimatoprost + timolol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have bimatoprost + timolol in stock, you can ask for one of the branded alternatives for bimatoprost + timolol.