- Medicine India
- Generic Medicines
- E
- Pharmacology For Escitalopram + Etizolam
Escitalopram + Etizolam Pharmacology
Escitalopram + Etizolam
About Escitalopram + EtizolamN/AMechanism of Action of Escitalopram + EtizolamN/APharmacokinets of Escitalopram + EtizolamN/AOnset of Action for Escitalopram + EtizolamN/ADuration of Action for Escitalopram + EtizolamN/AHalf Life of Escitalopram + EtizolamN/ASide Effects of Escitalopram + EtizolamN/AContra-indications of Escitalopram + EtizolamN/ASpecial Precautions while taking Escitalopram + EtizolamN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationNot recommended
NEONATES:ContraindicatedIndications for Escitalopram + Etizolam1.Depression
2.Anxiety
3.Obsessive compulsive disorder
4.Panic disorder
Interactions for Escitalopram + EtizolamN/ATypical Dosage for Escitalopram + EtizolamN/ASchedule of Escitalopram + EtizolamN/AStorage Requirements for Escitalopram + EtizolamN/AEffects of Missed Dosage of Escitalopram + EtizolamN/AEffects of Overdose of Escitalopram + EtizolamN/AEscitalopram
About EscitalopramSelective Serotonin Reuptake Inhibitor (SSRI), Antidepressant.Mechanism of Action of EscitalopramEscitalopram is the S enantiomer of racemic Citalopram. It is 100 times more potent than R-enantiomer. Escitalopram blocks the re-uptake of neurotransmitter Serotonin from the synapse to the presynaptic nerve terminal in the CNS. This potentiates the action of Serotonin (5HT) and it is useful in the treatment of depression.Pharmacokinets of EscitalopramAbsorption: Escitalopram is well absorbed after oral administration. Distribution: It is widely distributed in the body. Metabolism: Escitalopram undergoes metabolism in the liver and the metabolites are not as active as Escitalopram. Excretion: It is excreted mainly through urine.Onset of Action for Escitalopram1 weekDuration of Action for EscitalopramN/AHalf Life of Escitalopram27 - 32 hoursSide Effects of Escitalopram1.Nausea
2.Diarrhoea
3.Insomnia
4.Somnolence
5.Dry mouth
6.Fatigue
7.Increased sweating
8.Tremor
9.Dizziness
10.Agitation
11.Dyspepsia
12.Anorexia
13.Abdominal pain
14.Dysmenorrhea
15.Amenorrhea
16.Ejaculation disorder
17.Impotence
18.Polyuria
19.Upper respiratory tract infection
20.Fever
21.Myalgia
22.Arthralgia.Contra-indications of Escitalopram1. Hypersensitivity to Escitalopram or Citalopram
2. Patient on MAOI (Monoamine oxidase inhibitor) therapy.Special Precautions while taking Escitalopram1. Hepatic impairment
2. Renal impairment
3. Myocardial infarction
4. Cardiac failure
5. Epilepsy
6. Mania
7. Alcoholics
8. Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Escitalopram is started)
9. Use cautiously in patient at risk for suicide
10. Use caution while driving vehicle, operating machine and activities requiring mental alertness or judgment
11. Withdraw the drug gradually with caution
Pregnancy Related InformationContraindicated
Old Age Related InformationUse with cautionBreast Feeding Related InformationContraindicated
Children Related InformationContraindicated
NEONATES: contraindicated
Indications for EscitalopramDepression.Interactions for EscitalopramN/ATypical Dosage for EscitalopramAdult: Initial dose: 10 mg / day, dose can be increased to 20 mg / day if sufficient response does not occur after a minimum of 1 week.Schedule of EscitalopramHStorage Requirements for EscitalopramStore at 15 - 30 degree C. Keep out of the reach of children. Protect from heat and light.Effects of Missed Dosage of EscitalopramTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the doseEffects of Overdose of EscitalopramGive supportive measures and treatment. Drug can be removed from the body by gastric lavage. Absorption of the drug can be reduced by the administration of Activated charcoal.Etizolam
About EtizolamBenzodiazepine agonist, antianxiety, sedative and hypnotics.Mechanism of Action of EtizolamMainly acts on Limbic system and ascending reticular formation in the CNS and binds to BZD receptor.The bindig will facilitates GABA mediated chloride channel oppening and produce hyperpolarisatin.This will produce an increase in the concentration of the inhibitory neurotransmitter GABA and chloride ions and decrease firing rate of neuron.These in turn alters normal function of the body.Pharmacokinets of EtizolamAbsorption: It is well absorbrd after oral administration
Distribution: It is distributed widely in the body in protein bound form
Metabolism: It undergoes metabolism in the liver
Excretion: Excreted mainly in the urine
Onset of Action for Etizolam1 to 2 hrsDuration of Action for EtizolamN/AHalf Life of Etizolam6 hrsSide Effects of Etizolam1.Drowsiness
2.Vertigo
3.Visual disurbanace
4.Urinary retention and amnesia.Contra-indications of Etizolam1.Acute narrow-angle glaucoma
2.Resp depressio
3.Hepatic impairment
Special Precautions while taking Etizolam1.Renal impairmrnt
2.Hepatic impairment
3.Open angle glaucoma
4.Depression
5.Pulmonary insufficiancy
Pregnancy Related InformationContraindicated Old Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
Neonates- ContraindicatedIndications for Etizolam1.Insomnia
2.Anxiety
Interactions for EtizolamAlcohol and CNS depressants: Enhanced CNS effect
Itraconazole and fluvoxamine slow down the rate of elimination of etizolam leading to accumulation of etizolam and thus increased pharmacological effects.
Carbamazepine speeds up the metabolism of etizolam resulting in reduced pharmacological effects of etizolam.
Typical Dosage for EtizolamAdult : For anxiety: 0.50-1 mg two or three times per day (maximum 2 mg per day)
For insomnia: 1-2 mg before bedtime
Schedule of EtizolamHStorage Requirements for EtizolamStored in a light resistant tightly closed container.Effects of Missed Dosage of EtizolamN/AEffects of Overdose of EtizolamN/AHome Delivery for Escitalopram + Etizolam in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including escitalopram + etizolam.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for escitalopram + etizolam and other medicines and health products. Home delivery services for escitalopram + etizolam may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take escitalopram + etizolam only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for escitalopram + etizolam before they complete the sale. You can get this information while placing the order for escitalopram + etizolam with the pharmacy.
Escitalopram + Etizolam is a generic medicine name and there are several brands available for it. Some of the brands for escitalopram + etizolam might be better known than escitalopram + etizolam itself. If the pharmacy that's willing to deliver medicines to your home doesn't have escitalopram + etizolam in stock, you can ask for one of the branded alternatives for escitalopram + etizolam.