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- Pharmacology For Camylofin Dihydrochloride + Mefenamic Acid
Camylofin Dihydrochloride + Mefenamic Acid Pharmacology
Camylofin Dihydrochloride + Mefenamic Acid
About Camylofin Dihydrochloride + Mefenamic AcidN/AMechanism of Action of Camylofin Dihydrochloride + Mefenamic AcidN/APharmacokinets of Camylofin Dihydrochloride + Mefenamic AcidN/AOnset of Action for Camylofin Dihydrochloride + Mefenamic AcidN/ADuration of Action for Camylofin Dihydrochloride + Mefenamic AcidN/AHalf Life of Camylofin Dihydrochloride + Mefenamic AcidN/ASide Effects of Camylofin Dihydrochloride + Mefenamic AcidN/AContra-indications of Camylofin Dihydrochloride + Mefenamic AcidN/ASpecial Precautions while taking Camylofin Dihydrochloride + Mefenamic AcidN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
NEONATES:ContraindicatedIndications for Camylofin Dihydrochloride + Mefenamic Acid1.Intestinal colic
2.Renal colic
3.Biliary colic
4.Spasmodic
5.Dysmenorrhoea
Interactions for Camylofin Dihydrochloride + Mefenamic AcidN/ATypical Dosage for Camylofin Dihydrochloride + Mefenamic AcidN/ASchedule of Camylofin Dihydrochloride + Mefenamic AcidN/AStorage Requirements for Camylofin Dihydrochloride + Mefenamic AcidN/AEffects of Missed Dosage of Camylofin Dihydrochloride + Mefenamic AcidN/AEffects of Overdose of Camylofin Dihydrochloride + Mefenamic AcidN/ACamylofin dihydrochloride
About Camylofin dihydrochlorideSynthetic anticholinergic, direct smooth muscle relaxant.Mechanism of Action of Camylofin dihydrochlorideCamylofin dihydrochloride is a potent antispasmodic and is useful in active phase of labor. It accelerates the rate of cervical dilatation and shortens the duration of active phase of first stage of labor significantly without any undesirable effects on the fetus. It has no effect on the second and third stage of labor and no effect on uterine activity.Pharmacokinets of Camylofin dihydrochlorideN/AOnset of Action for Camylofin dihydrochlorideN/ADuration of Action for Camylofin dihydrochlorideN/AHalf Life of Camylofin dihydrochlorideN/ASide Effects of Camylofin dihydrochloride1. Dryness of mouth
2. Nausea
3. Vomiting
4. Drowsiness
5. Transient tachycardia
Contra-indications of Camylofin dihydrochloride1.Glucoma
2.Urinary retention (adynamic bladder)
3.Mega colon
4.Gastrointestinal haemorrhage
5.Tachyarrythmia.
Special Precautions while taking Camylofin dihydrochloride1.Urinary retention
2.Prostatic enlargement
3.Tachycardia
4.Cardiac insufficiency
5.Paralytic ileus
6.Ulcerative colitis
7.Pylonic stenosis
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Camylofin dihydrochloride1.Used as antispasmodic in biliary colic, renal and ureteric colic, dysmenorrhoea, peptic ulcer and chronic enterocolitis.Interactions for Camylofin dihydrochlorideN/ATypical Dosage for Camylofin dihydrochlorideAdult:
As antispasmodics: (IM or IV ) 0.285 to 0.857 mg / kg to be taken every 8 hours
Schedule of Camylofin dihydrochlorideN/AStorage Requirements for Camylofin dihydrochlorideN/AEffects of Missed Dosage of Camylofin dihydrochlorideThe doctor should be informed immediately if a dose is missedEffects of Overdose of Camylofin dihydrochlorideGive supportive measures and symptomatic treatmentMefenamic Acid
About Mefenamic AcidNSAID, Analgesic,antiinflammatory.Mechanism of Action of Mefenamic AcidMefenamic acid has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other analgesics. Mefenamic acid inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions.Pharmacokinets of Mefenamic AcidAbsorption: Mefenamic acid is well absorbed after oral administration. Distribution: It is distributed in the body in protein bound form. Metabolism: It is metabolised in the liver. Excretion: Mefenamic acid and its metabolites are excreted mainly in the urine.Onset of Action for Mefenamic Acid1-2 hours.Duration of Action for Mefenamic Acid6 hours.Half Life of Mefenamic Acid2-4 hours.Side Effects of Mefenamic Acid1.Nausea
2.Vomiting
3.Anorexia
4.Diarrhoea
5.Gastrointestinal bleeding
6.Abdominal distress
7.Constipation
8.Peptic ulcer
9.Dyspepsia
10.Headache
11.Flatulence
12.Drowsiness
13.Insomnia
14.Agranulocytosis
15.Aplastic anaemia
16.Thrombocytopenia
17.Dizziness
18.Rash
Contra-indications of Mefenamic Acid1.Hypersensitivity to Mefenamic acid and other NSAIDs
2.Inflammatory bowel disease
3.Peptic ulcer
Special Precautions while taking Mefenamic Acid1.Hepatic impairment
2.Renal impairment
3.Hypertension
4.Gastrointestinal diseases
5.Pre existing asthma
6.Patient on anticoagulant therapy
7.Heart failure
8.Myocardial infarction
9.StrokePregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationBelow 14 years: contraindicated
NEONATES: used only to close the patent ductus arteriosus as IV form only
Indications for Mefenamic Acid1.Muscular aches
2.Primary Dysmenorrhoea
3.Headaches
4.Acute gout
5.Dental pain
6.Patent ductus arteriosus
Interactions for Mefenamic AcidN/ATypical Dosage for Mefenamic AcidAdult: initial dose: 500 mg followed by 250 mg every 6 hours. Treatment is continued maximum up to 1 week.
Children above 14 years:
500 mg followed by 250 mg every 6 hours. Treatment is continued maximum up to 1 week.
Children below 14 years: not recommended.
Schedule of Mefenamic AcidHStorage Requirements for Mefenamic AcidStore Mefenamic acid at room temperature in a tightly closed light resistant container.Effects of Missed Dosage of Mefenamic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Mefenamic AcidGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal.
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Camylofin Dihydrochloride + Mefenamic Acid is a generic medicine name and there are several brands available for it. Some of the brands for camylofin dihydrochloride + mefenamic acid might be better known than camylofin dihydrochloride + mefenamic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have camylofin dihydrochloride + mefenamic acid in stock, you can ask for one of the branded alternatives for camylofin dihydrochloride + mefenamic acid.