Diflorasone Diacetate Pharmacology

Diflorasone Diacetate

About Diflorasone Diacetate
Topical Steroid
Mechanism of Action of Diflorasone Diacetate
The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Pharmacokinets of Diflorasone Diacetate
1.Absorption: Percutaneous absorption is increased when the skin is inflammed or occlusive dressing is used.
2.Metabolism: Once absorbed systemically, it is metabolised hepatically.
3.Excretion: Once absorbed systemically, it is excreted renally.
Onset of Action for Diflorasone Diacetate
N/A
Duration of Action for Diflorasone Diacetate
N/A
Half Life of Diflorasone Diacetate
N/A
Side Effects of Diflorasone Diacetate
1.Burning sensation
2.Itching
3.Redness
4.Dryness
5.Folliculitis
6.Hypertrichosis
8.Hypopigmentation
9.Perioral dermatitis
10.Allergic contact dermatitis
11.Skin atrophy
12.Striae
13.Miliaria
Contra-indications of Diflorasone Diacetate
N/A
Special Precautions while taking Diflorasone Diacetate
1.Substantial systemic absorption may lead to reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycaemia and glucosuria.
2.Treatment should be discontinued if there is irritation.
3.Avoid contact with eyes
4.Do not use cream on face
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Not recommended
Indications for Diflorasone Diacetate
For relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
Interactions for Diflorasone Diacetate
N/A
Typical Dosage for Diflorasone Diacetate
Topical/Cutaneous:Adult: As 0.05% ointment/cream: Apply a thin film over the affected areas 1-4 times daily depending on the severity of the condition.
Schedule of Diflorasone Diacetate
N/A
Storage Requirements for Diflorasone Diacetate
Topical/Cutaneous: Store at 20-25?C.
Effects of Missed Dosage of Diflorasone Diacetate
N/A
Effects of Overdose of Diflorasone Diacetate
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms may include blurred vision or other vision changes; muscle weakness; severe or persistent headache; symptoms of high blood sugar (eg, increased thirst or urination, confusion, unusual drowsiness); or unusual weight gain, especially in the face.

Home Delivery for Diflorasone Diacetate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including diflorasone diacetate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for diflorasone diacetate and other medicines and health products. Home delivery services for diflorasone diacetate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take diflorasone diacetate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for diflorasone diacetate before they complete the sale. You can get this information while placing the order for diflorasone diacetate with the pharmacy.

Diflorasone Diacetate is a generic medicine name and there are several brands available for it. Some of the brands for diflorasone diacetate might be better known than diflorasone diacetate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have diflorasone diacetate in stock, you can ask for one of the branded alternatives for diflorasone diacetate.