- Medicine India
- Generic Medicines
- D
- Pharmacology For Diclofenac sodium + Methyl Salicylate + Menthol + Camphor
Diclofenac sodium + Methyl Salicylate + Menthol + Camphor Pharmacology
Diclofenac sodium + Methyl Salicylate + Menthol + Camphor
About Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/AMechanism of Action of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/APharmacokinets of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/AOnset of Action for Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/ADuration of Action for Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/AHalf Life of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/ASide Effects of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorIn rare instances, skin sensitivity may develop. Should this occur, discontinue immediately.Contra-indications of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/ASpecial Precautions while taking Diclofenac sodium + Methyl Salicylate + Menthol + Camphor1.Do not apply to broken skin and excessively raw areas.
2.For external use only.
3.Avoid contact with eyes.
4.Exercise care with sensitive skins.
Pregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Diclofenac sodium + Methyl Salicylate + Menthol + Camphor1.Temporary relief of minor aches and pains of muscles and joints due to muscle strains, sprains and bruises or over exertion.
2.As an adjunct in the management of minor stiffness or soreness associated with arthritis, rheumatism, lumbago, fibrositis, sciatica and stiff neck.
Interactions for Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/ATypical Dosage for Diclofenac sodium + Methyl Salicylate + Menthol + CamphorApply by hand and gently massage the Gel into the area of pain or stiffness and on the surrounding area.Schedule of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/AStorage Requirements for Diclofenac sodium + Methyl Salicylate + Menthol + CamphorStore in a cool, dark place.Do not Freeze.Effects of Missed Dosage of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/AEffects of Overdose of Diclofenac sodium + Methyl Salicylate + Menthol + CamphorN/ADiclofenac Sodium
About Diclofenac SodiumN/AMechanism of Action of Diclofenac SodiumDiclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (PGs). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake. .Pharmacokinets of Diclofenac SodiumAbsorption: Diclofenac sodium is rapidly absorbed after oral administration. It undergoes first pass metabolism and its bioavailability is 50 % only. Distribution: It is distributed in highly protein bound form. Metabolism: Diclofenac sodium is metabolised in the liver. Excretion: Drug and metabolites are primarily excreted in urine and some amount in the bile.Onset of Action for Diclofenac Sodium1- 4.5 hoursDuration of Action for Diclofenac SodiumHoursHalf Life of Diclofenac Sodium2 hoursSide Effects of Diclofenac Sodium1.Nausea
2.Vomiting
3.Anorexia
4.Diarrhoea
5.Gastrointestinal bleeding
6.Abdominal distress
7.Constipation
8.Flatulence
9.Ulceration of the stomach or intestine
10.Dyspepsia
11.Headache
12.Dizziness
13. Rash
Contra-indications of Diclofenac Sodium1.Hypersensitivity to Indomethacin and other Non steroidal anti inflammatory drugs(NSAID)
2.Peptic ulcer
3.Asthma
Special Precautions while taking Diclofenac Sodium1.Hepatic impairment
2.Renal impairment
3.Hypertension
4.Blood clotting disorders
5.Gastrointestinal diseases
6.Proctitis
7.Asthma
8.Cautioned against driving, operating or activities requiring concentration
9.Avoid alcohol
10.Heart failure
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
CHILDREN below 14: contraindicatedIndications for Diclofenac Sodium1.Ankylosing spondylitis
2.Acute gout
3.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints
4.Osteoarthritis
5.For the relief of pain and inflammation in dental minor surgery and orthopedic
6.Dysmenorrhoea
7.Juvenile chronic arthritis
8.Migraine
Interactions for Diclofenac SodiumLithium & Digoxin : Blood levels of lithium and digoxin increased leading to enhanced efficacy and posible toxicity.
Diuretics : Inhibits diuretics but efficacy of potassium sparing diuretics enhanced.
Methotrexate : Toxicity enhanced.
Salicylates : Efficacy of salicylates reduced.
Cyclosporine : Increases nephrotoxicity of both agents.
Hydantoins : Increases serum levels resulting in toxicity.
Typical Dosage for Diclofenac SodiumAdult: 100 - 150 mg / day in 2 - 3 divided doses.
For the relief of pain, Migraine, Dysmenorrhoea: 150 mg / day in 3 divided doses.
Osteoarthritis: 50 mg 2 - 3 times daily
Rheumatoid arthritis: 150 - 200 mg / day in 3 - 4 divided doses.
Ankylosing spondylitis: 25 mg 4 times daily give an extra dose of 25 mg at bed time if necessary.
Children Juvenile rheumatoid arthritis: 0.5 - 2 mg / kg body weight / day in divided doses.
Maximum dose: 3 mg / kg body weight / day in divided doses
Schedule of Diclofenac SodiumHStorage Requirements for Diclofenac SodiumStore Diclofenac sodium at room temperature in a tightly closed light resistant container.Effects of Missed Dosage of Diclofenac SodiumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Diclofenac SodiumGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal.Methyl salicylate
About Methyl salicylateSalicylates, Rubefacient, counterirritant.Mechanism of Action of Methyl salicylateMethyl salicylate is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.Pharmacokinets of Methyl salicylateN/AOnset of Action for Methyl salicylateN/ADuration of Action for Methyl salicylateN/AHalf Life of Methyl salicylateN/ASide Effects of Methyl salicylateN/AContra-indications of Methyl salicylateN/ASpecial Precautions while taking Methyl salicylateN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Methyl salicylateN/AInteractions for Methyl salicylateN/ATypical Dosage for Methyl salicylateN/ASchedule of Methyl salicylateN/AStorage Requirements for Methyl salicylateN/AEffects of Missed Dosage of Methyl salicylateN/AEffects of Overdose of Methyl salicylateN/AMenthol
About MentholTerpenes and terpenoid, Antipruritic, decongestant, topical analgesic.Mechanism of Action of MentholMenthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and mild local anaesthetic effect relieves itching. It has good soothing effect and acts as a demulcent. It also acts as a carminative.Pharmacokinets of MentholN/AOnset of Action for MentholN/ADuration of Action for MentholN/AHalf Life of MentholN/ASide Effects of Menthol1.Irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
12.Contact dermatitis
13.Allergic reactions
Contra-indications of Menthol1. Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Menthol1.Should not apply Menthol directly in to or near the nostrils of small children or asthma patients
2.Prolonged use
3.Seizures
4.Should not take steam inhalation orally
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with caution
Children Related InformationUse with caution
below 2 years: ContraindicatedIndications for Menthol1. Rubefacient.
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5.Sore throat
6.Cold sores
7.Hay fever
8.As an inhalant to relieve nasal, bronchial, or upper respiratory congestion
9.Sinusitis
10.Bronchial cough
11.Pharyngeal inflammation
Interactions for MentholN/ATypical Dosage for MentholDosage individualized based on requirements of the patient.
Lozenges: Dissolve lozenge (5%-10% menthol) slowly in the mouth hourly as needed by the patients.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Menthol (3.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1tsp of solution for each pint, up to thrice daily
Schedule of MentholN/AStorage Requirements for MentholStore at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.Effects of Missed Dosage of MentholTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MentholProvide symptomatic treatment and supportive measures.Camphor
About CamphorN/AMechanism of Action of CamphorCamphor acts as a rubefacient when it is rubbed on the skin and causes localized vasodilatation; which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and a mild local anaesthetic effect and relieves itching. When ingested in small amounts, it creates feelings of warmth and comfort in the epigastrium. Camphor acts as a local anesthetic on the respiratory passageways and causing cough suppression.Pharmacokinets of CamphorAbsorption: Well absorbed through the skin, Distribution: Widely distributed in the body and crosses the placenta, Metabolism: Metabolized in liver, Excretion: Excreted mainly through urine and a minor portion is excreted through lungs.Onset of Action for CamphorN/ADuration of Action for CamphorN/AHalf Life of CamphorN/ASide Effects of Camphor1.Gastric irritation
2.Anxiety
3.Excitement
4.Delirium
5.Colic
6.Nausea
7.Vomiting
8.Diarrhoea
9.Convulsions
10.Apnoea
11.Asystole
Contra-indications of Camphor1.Hypersensitivity to the drug
2.Should not applies to broken, injured, or burned skin
Special Precautions while taking Camphor1.Should not apply camphor directly in to or near the nostrils of small children or asthma patients
2.Prolonged use may lead to accumulation in adipose tissue
3.Seizures.
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
Children (below 2 years): ContraindicatedIndications for Camphor1.Rubefacient
2.Ingredient in cough preparations
3.Antipruritic
4. Ingredient in ointment or liniment to treat sprains; joint and muscle pain
5. As balm for chapped lips, cold sores
6.As an inhalant to relieve nasal, bronchial or upper respiratory congestion.
Interactions for CamphorN/ATypical Dosage for CamphorDosage individualized based on requirement and condition of the patient.
Topical: Rubbed on the throat and chest in a layer loosely covered with a warm dry cloth; up to thrice daily.
In vaporizer: Camphor (6.2%) in a hot steam vaporizer can be used by adding 1 tbsp of solution for each quart of cold water, or 1 tsp of solution for each pint, up to thrice daily.Schedule of CamphorN/AStorage Requirements for CamphorStore at a cool dry place in a well closed container. Protect from light and heat. Keep out of reach of children.Effects of Missed Dosage of CamphorTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of CamphorProvide symptomatic treatment and supportive measures.
Ingestion: If camphor has been ingested recently, and the condition of the patient allows, perform gastric lavage. If only small amounts have been ingested, administer cathartics.
Inhalation: If camphor has been inhaled, remove patient from exposure, administer fresh air or oxygen, and establish respiration.
Topical: If there has been external contact with camphor, wash skin thoroughly with soap and water. Irrigate eyes with plenty of water.
In severe poisoning: Assist respiration in respiratory depression. Perform artificial respiration if required. Treat convulsions with diazepam or other suitable drugs. Protect the airway by endotracheal intubation or suitable measures, Perform gastric lavage and reduce absorption by administration of activated charcoal, and then a saline cathartic if required. Resin and charcoal haemoperfusion may be used in severe cases.
Home Delivery for Diclofenac sodium + Methyl Salicylate + Menthol + Camphor in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including diclofenac sodium + methyl salicylate + menthol + camphor.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for diclofenac sodium + methyl salicylate + menthol + camphor and other medicines and health products. Home delivery services for diclofenac sodium + methyl salicylate + menthol + camphor may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take diclofenac sodium + methyl salicylate + menthol + camphor only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for diclofenac sodium + methyl salicylate + menthol + camphor before they complete the sale. You can get this information while placing the order for diclofenac sodium + methyl salicylate + menthol + camphor with the pharmacy.
Diclofenac sodium + Methyl Salicylate + Menthol + Camphor is a generic medicine name and there are several brands available for it. Some of the brands for diclofenac sodium + methyl salicylate + menthol + camphor might be better known than diclofenac sodium + methyl salicylate + menthol + camphor itself. If the pharmacy that's willing to deliver medicines to your home doesn't have diclofenac sodium + methyl salicylate + menthol + camphor in stock, you can ask for one of the branded alternatives for diclofenac sodium + methyl salicylate + menthol + camphor.