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- Pharmacology For Cefadroxil + Clavulanic Acid
Cefadroxil + Clavulanic Acid Pharmacology
Cefadroxil + Clavulanic Acid
About Cefadroxil + Clavulanic AcidN/AMechanism of Action of Cefadroxil + Clavulanic AcidN/APharmacokinets of Cefadroxil + Clavulanic AcidN/AOnset of Action for Cefadroxil + Clavulanic AcidN/ADuration of Action for Cefadroxil + Clavulanic AcidN/AHalf Life of Cefadroxil + Clavulanic AcidN/ASide Effects of Cefadroxil + Clavulanic AcidN/AContra-indications of Cefadroxil + Clavulanic AcidN/ASpecial Precautions while taking Cefadroxil + Clavulanic AcidN/APregnancy Related InformationUse with cautionOld Age Related InformationMay be usedBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Cefadroxil + Clavulanic AcidFor the treatment of the following infections (skin, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staphylococci and Streptococcus pyogenes and penicillinase(beta lactamases) producing bacterial infections.Interactions for Cefadroxil + Clavulanic AcidN/ATypical Dosage for Cefadroxil + Clavulanic AcidN/ASchedule of Cefadroxil + Clavulanic AcidN/AStorage Requirements for Cefadroxil + Clavulanic AcidN/AEffects of Missed Dosage of Cefadroxil + Clavulanic AcidN/AEffects of Overdose of Cefadroxil + Clavulanic AcidN/ACefadroxil
About CefadroxilFirst Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibioticMechanism of Action of CefadroxilCefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil
Pharmacokinets of CefadroxilAbsorption: well absorbed orally, Distribution: widely distributed, Metabolism: not metabolized, Excretion: excreted mainly through urine; & small amount is excreted in breast milk.Onset of Action for CefadroxilWithin one hourDuration of Action for CefadroxilUp to16 hoursHalf Life of CefadroxilN/ASide Effects of Cefadroxil1.Nausea
2.Vomiting
3.Diarrhea
4.Gastritis
5.Super infection
6.Candidiasis
7.Rash
8.Hypersensitivity reactions
9.Angioedema
10.Vaginitis
11.Neutropenia
12.Thrombocytopenia
13.Headache
14.Dizziness
15.Hallucinations
16.Nephritis
17.Elevated liver enzymes.Contra-indications of Cefadroxil1.Hypersensitivity to cephalosporins
2.Porphyria
3.Neuromuscular disorders.
Special Precautions while taking Cefadroxil1.Renal impairment
2.Patient allergic to penicillins
3.Neuromuscular disorders
Pregnancy Related InformationUse with caution.Old Age Related InformationMay be used.Breast Feeding Related InformationUse with caution.Children Related InformationMay be used.Indications for Cefadroxil1. Urinay tract infections
2. Tonsillitis & Pharyngitis
3. Skin &soft tissue infections
4. Otitis media.
Interactions for CefadroxilAminoglycosides (Gentamycin, Tobramycin): Nephrotoxicity of aminoglycosides potentiated.
Oral anticoagulants: Hypoprothrombinaemic effect potentiated, bleeding complications may occur.
Bacteriostatic Agents like Chloramphenicol: Decrease efficacy of Cefadroxil.
Probenecid: Slows tubular excretion and this enhances efficacy.
Frusemide & Ethacrynic Acid: Potentiate Nephrotoxicity of Cefadroxil.
Urine Glucose: False positive with Benedicts solution and Fehlings solution.
Direct Coomb?s Test: False positive.
Urinary 17-Ketosteroid values: Falsely elevated values.
Typical Dosage for CefadroxilAdults:500mg to 1gm 12 hourly
Children:30mg/kg/day two times daily
Schedule of CefadroxilHStorage Requirements for CefadroxilStore in a cool place.
Effects of Missed Dosage of CefadroxilTake the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.Effects of Overdose of CefadroxilSymptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measuresClavulanic acid
About Clavulanic acidBeta-Lactamase Inhibitor, Antibiotic resistance reducer to penicillin group.Mechanism of Action of Clavulanic acidN/APharmacokinets of Clavulanic acidN/AOnset of Action for Clavulanic acidN/ADuration of Action for Clavulanic acidN/AHalf Life of Clavulanic acidN/ASide Effects of Clavulanic acidN/AContra-indications of Clavulanic acidN/ASpecial Precautions while taking Clavulanic acidN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Clavulanic acidN/AInteractions for Clavulanic acidN/ATypical Dosage for Clavulanic acidN/ASchedule of Clavulanic acidN/AStorage Requirements for Clavulanic acidN/AEffects of Missed Dosage of Clavulanic acidN/AEffects of Overdose of Clavulanic acidN/AHome Delivery for Cefadroxil + Clavulanic Acid in Your City
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Cefadroxil + Clavulanic Acid is a generic medicine name and there are several brands available for it. Some of the brands for cefadroxil + clavulanic acid might be better known than cefadroxil + clavulanic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cefadroxil + clavulanic acid in stock, you can ask for one of the branded alternatives for cefadroxil + clavulanic acid.