Difluprednate (Eye Pre) Pharmacology

Difluprednate (Eye Pre)

About Difluprednate (Eye Pre)
Topical anti-infammatory corticosteroid for ophthalmic use.
Mechanism of Action of Difluprednate (Eye Pre)
Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins (lipocortins). It is postulated that these proteins control the biosynthesis of potent mediators of infammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Pharmacokinets of Difluprednate (Eye Pre)
1.Absorption: Difluprednate penetrates the corneal epithelium rapidly and effectively. The systemic absorption of difuprednate after ocular instillation of difluprednate is limited.
2.Metabolism:Difluprednate is rapidly deacetylated in the aqueous humor to difluoroprednisolone butyrate (DFB), the drug?s active metabolite. Endogenous tissue esterases then metabolize DFB to the inert metabolite hydroxyfluoroprednisolone butyrate (HFB), which limits systemic exposure to the active compound.
Onset of Action for Difluprednate (Eye Pre)
N/A
Duration of Action for Difluprednate (Eye Pre)
N/A
Half Life of Difluprednate (Eye Pre)
N/A
Side Effects of Difluprednate (Eye Pre)
1.Temporary blurred vision may occur
2.Prolonged use may result in a new fungal infection
Contra-indications of Difluprednate (Eye Pre)
1.Infectious dermatoses.
2.Hyper sensitivity
3.Active mycobacterial, viral or fungal eye infections
Special Precautions while taking Difluprednate (Eye Pre)
1.Eye infection (including viral infections such as herpes simplex keratitis)
2.Cataracts
3.Glaucoma
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Not recommended
Indications for Difluprednate (Eye Pre)
1.For the treatment of inflammation and pain associated with ocular surgery.
2.Inflammations of eye
3.Allergic Conjunctivitis

Interactions for Difluprednate (Eye Pre)
N/A
Typical Dosage for Difluprednate (Eye Pre)
1.Ophthalmic solution:0.05%
2.Ocular Inflammation & Pain: Initate 24 hours postop: Instill 1 gtt in affected eye(s) QID x2 weeks, then BID x1 week, then taper and discontinue
Schedule of Difluprednate (Eye Pre)
N/A
Storage Requirements for Difluprednate (Eye Pre)
Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light.
Effects of Missed Dosage of Difluprednate (Eye Pre)
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Effects of Overdose of Difluprednate (Eye Pre)
Seek emergency medical attention if used too much of this medicine. An overdose of difluprednate is not likely to cause life-threatening symptoms.

Home Delivery for Difluprednate (Eye Pre) in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for difluprednate (eye pre) and other medicines and health products. Home delivery services for difluprednate (eye pre) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take difluprednate (eye pre) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for difluprednate (eye pre) before they complete the sale. You can get this information while placing the order for difluprednate (eye pre) with the pharmacy.

Difluprednate (Eye Pre) is a generic medicine name and there are several brands available for it. Some of the brands for difluprednate (eye pre) might be better known than difluprednate (eye pre) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have difluprednate (eye pre) in stock, you can ask for one of the branded alternatives for difluprednate (eye pre).