- Medicine India
- Generic Medicines
- L
- Pharmacology For Levocetirizine + Montelukast + Ambroxol
Levocetirizine + Montelukast + Ambroxol Pharmacology
Levocetirizine + Montelukast + Ambroxol
About Levocetirizine + Montelukast + AmbroxolN/AMechanism of Action of Levocetirizine + Montelukast + AmbroxolN/APharmacokinets of Levocetirizine + Montelukast + AmbroxolN/AOnset of Action for Levocetirizine + Montelukast + AmbroxolN/ADuration of Action for Levocetirizine + Montelukast + AmbroxolN/AHalf Life of Levocetirizine + Montelukast + AmbroxolN/ASide Effects of Levocetirizine + Montelukast + AmbroxolN/AContra-indications of Levocetirizine + Montelukast + AmbroxolN/ASpecial Precautions while taking Levocetirizine + Montelukast + AmbroxolN/APregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationNot recommendedIndications for Levocetirizine + Montelukast + Ambroxol1.Allergic cough
2.Asthma
Interactions for Levocetirizine + Montelukast + AmbroxolN/ATypical Dosage for Levocetirizine + Montelukast + AmbroxolN/ASchedule of Levocetirizine + Montelukast + AmbroxolN/AStorage Requirements for Levocetirizine + Montelukast + AmbroxolN/AEffects of Missed Dosage of Levocetirizine + Montelukast + AmbroxolN/AEffects of Overdose of Levocetirizine + Montelukast + AmbroxolN/ALevocetirizine
About LevocetirizineA third-generation non-sedative H1 antagonist, Antihistamine.Mechanism of Action of LevocetirizineThis active enantiomer of cetrizine is a potent, nonsedative and selective H1 receptor antagonist. It antagonizes the allergic symptoms produced by histamines like runny nose, cold, cough etc. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.Pharmacokinets of LevocetirizineAbsorption- Well absorbed after oral administration.
Distribution-Widely distributed in the body.90% bound to the plasma proteins.
Metabolism- Metabolized in the liver to its metabolites.
Excretion- Excreted via urine and feces.
Onset of Action for LevocetirizineN/ADuration of Action for LevocetirizineN/AHalf Life of LevocetirizineIts plasma half life is 6-10hrsSide Effects of Levocetirizine1. Headache
2. Abdominal pain
3. Dry mouth
4. Fatigue
5. Pharyngitis
6. Sleepiness
7. Asthenia
8. Rhinitis causing a blocked or runny nose
9. Migraine
Contra-indications of Levocetirizine1. Allergy to drug or other medicines that contain piperazine derivatives
2. Hereditary galactose intolerance
3. Hereditary Lapp lactase deficiency
4. Inherited glucose-galactose malabsorption
5. Severely decreased kidney function
Special Precautions while taking Levocetirizine1. Decreased kidney function
2. Avoid alcohol or any work which require mental alertness like driving and machine operation during treatment.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Levocetirizine1. Rhinitis (seasonal and perennial)
2. Idiopathic urticaria
Interactions for LevocetirizineCoadministration with alcohol or other CNS depressants may have additional CNS depressant effect. Typical Dosage for LevocetirizineOral-
Adult-5mg/day.
Children (>6yrs) - 5mg/day. Schedule of LevocetirizineN/AStorage Requirements for LevocetirizineStore in a cool, dry place, away from direct light and heat.
Keep out of reach of children.
Effects of Missed Dosage of LevocetirizineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of LevocetirizineGive symptomatic and supportive treatment.Montelukast
About MontelukastLeukotriene(CysLT1) Receptor Antagonist, Antiinflammatory,antiasthma.Mechanism of Action of MontelukastMontelukast is competitively and selectively antagonizes CysLT1 receptor (leukotrienes receptor) mediated Bronchoconstriction.Montelukast inhibits physiologic actions of LTD 4 at the CysLT1 receptor without any agonist activity.
Pharmacokinets of MontelukastAbsorption: Montelukast is rapidly absorbed after oral administration and its bioavailability is about 60 - 70%.
Distribution: It is minimally distributed to the tissues in protein bound form (99%)
Metabolism: It is extensively metabolised in the liver.
Excretion: Montelukast is excreted in the faeces.
Onset of Action for MontelukastN/ADuration of Action for MontelukastN/AHalf Life of Montelukast2.75 - 5.5 hoursSide Effects of Montelukast1.Headache
2.Dizziness
3.Nasal congestion
4.Sore throat
5.Abdominal pain
6.Fatigue
7.Asthenia
8.Cough
9.Influenza
10.Rash
11.Fever
12.Trauma
13.Trauma
14.Dyspepsia
Contra-indications of Montelukast1.Hypersensitivity to Montelukast
2.Acute asthmatic attacksSpecial Precautions while taking MontelukastN/APregnancy Related InformationUse with caution.Old Age Related InformationMay be used.Breast Feeding Related InformationUse with caution.Children Related InformationMay be used
CHILDREN below 6 years : contraindicated
NEONATES: contraindicated
Indications for MontelukastAsthma.Interactions for MontelukastBarbiturates & Primidone: Plasma concentration of montelukast is reduced by phenobarbital.
Typical Dosage for MontelukastAdult: 10 mg / day at bed time
Children (6 - 14 years): 5mg/day at bed time
Schedule of MontelukastN/AStorage Requirements for MontelukastStore at room temperature. Protect from heat and light. Keep out of the reach of children.Effects of Missed Dosage of MontelukastTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MontelukastGive supportive measures and symptomatic treatmentAmbroxol
About AmbroxolActive N-desmethyl metabolite of bromhexine,systemically active mucolytic agent, Secretomotoric and expectoration improver.Mechanism of Action of AmbroxolAmbroxol hydrochloride acts as an expectoration improver and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and by breaking network of fibres in tenacious sputum . It induces thin copious bronchial secretion and possesses antioxidant properties.Pharmacokinets of AmbroxolN/AOnset of Action for AmbroxolN/ADuration of Action for AmbroxolN/AHalf Life of AmbroxolN/ASide Effects of Ambroxol1. Rhinorrhoea
2. Lacrimations
3. Allergic reactions
4. Gastric irritation.Contra-indications of AmbroxolHypersensitivity to the Ambroxol hydrochloride or Bromhexine.Special Precautions while taking Ambroxol1.Hepatic impairment
2.Renal impairment
3.Gastric and duodenal ulcer
4.Convulsive disorders
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Ambroxol1. As Expectorant and mucolytic
2. Conditions associated with production of viscid mucous
3. Bronchitis
4. Pharyngitis
5. Laryngitis
6. Rhinitis
7. Sinusitis
8. Asthmatic bronchitis
9. Mucous bronchiectasis
10. Chronic Pneumonia.Interactions for AmbroxolN/ATypical Dosage for AmbroxolOral: 15mg to 30mg three times daily.
Children (6 to 12years): 5ml 2 to 3 times daily
Children (2 to 6years): 2.5ml thrice daily. (5ml liquid contains 30mg Ambroxol hydrochloride)
Children up to 2 years: 7.5mg two times daily
Schedule of AmbroxolHStorage Requirements for AmbroxolStore in a cool dry place and protect from light. Keep out of reach of children.Effects of Missed Dosage of AmbroxolTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of AmbroxolProvide symptomatic treatment and supportive measures.Home Delivery for Levocetirizine + Montelukast + Ambroxol in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including levocetirizine + montelukast + ambroxol.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for levocetirizine + montelukast + ambroxol and other medicines and health products. Home delivery services for levocetirizine + montelukast + ambroxol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take levocetirizine + montelukast + ambroxol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for levocetirizine + montelukast + ambroxol before they complete the sale. You can get this information while placing the order for levocetirizine + montelukast + ambroxol with the pharmacy.
Levocetirizine + Montelukast + Ambroxol is a generic medicine name and there are several brands available for it. Some of the brands for levocetirizine + montelukast + ambroxol might be better known than levocetirizine + montelukast + ambroxol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have levocetirizine + montelukast + ambroxol in stock, you can ask for one of the branded alternatives for levocetirizine + montelukast + ambroxol.