Zinc oxide + Magnesium + Calcium + Calcitriol Pharmacology

Zinc oxide + Magnesium + Calcium + Calcitriol

About Zinc oxide + Magnesium + Calcium + Calcitriol

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Mechanism of Action of Zinc oxide + Magnesium + Calcium + Calcitriol

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Pharmacokinets of Zinc oxide + Magnesium + Calcium + Calcitriol

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Onset of Action for Zinc oxide + Magnesium + Calcium + Calcitriol

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Duration of Action for Zinc oxide + Magnesium + Calcium + Calcitriol

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Half Life of Zinc oxide + Magnesium + Calcium + Calcitriol

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Side Effects of Zinc oxide + Magnesium + Calcium + Calcitriol

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Contra-indications of Zinc oxide + Magnesium + Calcium + Calcitriol

1.Hypercalcemia
2.Evidence of vitamin d toxicity
3.Dietary supplement

Special Precautions while taking Zinc oxide + Magnesium + Calcium + Calcitriol

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Pregnancy Related Information

Use with caution

Old Age Related Information

N/A

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Zinc oxide + Magnesium + Calcium + Calcitriol

Hypocalcemia

Interactions for Zinc oxide + Magnesium + Calcium + Calcitriol

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Typical Dosage for Zinc oxide + Magnesium + Calcium + Calcitriol

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Schedule of Zinc oxide + Magnesium + Calcium + Calcitriol

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Storage Requirements for Zinc oxide + Magnesium + Calcium + Calcitriol

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Calcium/Magnesium/Vitamin D out of the reach of children and away from pets.

Effects of Missed Dosage of Zinc oxide + Magnesium + Calcium + Calcitriol

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Effects of Overdose of Zinc oxide + Magnesium + Calcium + Calcitriol

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Zinc oxide

About Zinc oxide

Zinc compound, A sunscreen,antipruritic.

Mechanism of Action of Zinc oxide

It works by providing a skin barrier and helps in healing and prevent skin irritation. It acts as a sunscreen which absorbs incident solar radiation in the UVA ranges and reduces its transmission to the skin.

Pharmacokinets of Zinc oxide

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Onset of Action for Zinc oxide

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Duration of Action for Zinc oxide

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Half Life of Zinc oxide

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Side Effects of Zinc oxide

1.Rash
2.Hives
3.Difficulty breathing
4.Tightness in the chest
5.Swelling of the mouth, face, lips, or tongue
6.Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
7.Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.

Contra-indications of Zinc oxide

1.Hypersensitivity to Zinc oxide
2.Allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Special Precautions while taking Zinc oxide

1.Allergic to Zinc preparations
2.Zinc oxide topical will not treat a bacterial or fungal infection
3.Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper
4.Avoid getting this medication in your mouth or eyes
5.Do not use zinc oxide topical on deep skin wounds or severe burns

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

N/A

Indications for Zinc oxide

1.To prevent minor skin irritations such as burns, cuts, poison ivy, poison oak, poison sumac, and diaper rash.
2.As sunscreen
3.Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
4.Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements

Interactions for Zinc oxide

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Typical Dosage for Zinc oxide

Apply the medicament to the affected part 2 times daily.

Schedule of Zinc oxide

N/A

Storage Requirements for Zinc oxide

Store at 15 - 30 degree C.Protect from heat,light and moisture.Keep out of the reach of children.

Effects of Missed Dosage of Zinc oxide

Apply the missed dose as soon as noticed.

Effects of Overdose of Zinc oxide

Give supportive measures and symptomatic treatment.

Magnesium

About Magnesium

Magnesium is essential for enzyme activity, calcium and potassium uptake, nerve transmission, bone formation and metabolism of carbohydrates and minerals. It is magnesium, not calcium, which helps form hard tooth enamel, resistant to decay. Like calcium and chloride, magnesium also plays a role in regulating the acid-alkaline balance in the body. High magnesium levels in drinking water have been linked to resistance to heart disease. Although it is found in many foods, including dairy products, nuts, vegetables, fish, meat and seafood, deficiencies are common in America due to soil depletion, poor absorption and lack of minerals in drinking water. A diet high in carbohydrates, oxalic acid in foods like raw spinach and phytic acid found in whole grains can cause deficiencies. An excellent source of usable magnesium is beef, chicken or fish broth. High amounts of zinc and vitamin D increase magnesium requirements. Magnesium deficiency can result in coronary heart disease, chronic weight loss, obesity, fatigue, epilepsy and impaired brain function. Chocolate cravings are a sign of magnesium deficiency.

Mechanism of Action of Magnesium

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Pharmacokinets of Magnesium

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Onset of Action for Magnesium

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Duration of Action for Magnesium

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Half Life of Magnesium

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Side Effects of Magnesium

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Contra-indications of Magnesium

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Special Precautions while taking Magnesium

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Magnesium

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Interactions for Magnesium

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Typical Dosage for Magnesium

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Schedule of Magnesium

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Storage Requirements for Magnesium

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Effects of Missed Dosage of Magnesium

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Effects of Overdose of Magnesium

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Calcium

About Calcium

Calcium is necessary for cardiac function, muscle contraction, nervous activity, coagulation of blood and for maintaining structural integrity of cell membranes.
Plasma concentration of calcium is kept in normal range by three endocrine factors which control metabolism of calcium. These are (a) Parathyroid hormone, (b) Calcitonin, (c) Vitamin D. Calcium in plasma is bound to albumin, is complexed with anions (e.g. phosphate) and as diffusible ionic calcium. The physiological effects are exerted by ionic calcium. The predominant source of calcium is dairy products and the daily intake varies from 200 - 2500 mg. Adequate calcium intake is particularly important during periods of bone growth in childhood and adolescence and during pregnancy and lactation.
Patients with advanced renal insufficiency exhibit phosphate retention and some degree of hyperphosphataemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy and soft tissue calcification. Calcium acetate, when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the faeces.
Deficiency signs and symptoms: Osteoporosis, pathological fractures, brittle nails and hair.

Mechanism of Action of Calcium

Calcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and
A-V conduction. Calcium is also required for blood-coagulation.

Pharmacokinets of Calcium

Absorption: Actively absorbed from gastrointestinal tract in an ionized form; and vitamin D in it`s active form is required for calcium absorption, Distribution: Distributed mainly in to skeletal tissue (99%) and 1% is distributed equally between the intracellular and extra cellular fluid. CSF levels are about half of the serum calcium levels, Metabolism: Not significantly metabolized in the body, Excretion: Excreted mainly through faeces and a small amount is excreted through urine.

Onset of Action for Calcium

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Duration of Action for Calcium

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Half Life of Calcium

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Side Effects of Calcium

1.Constipation
2.Bloating
3.Excess gas
4.Anorexia
5.Nausea
6.Vomiting
7.Abdominal pain
8.Thirst
9.Hypercalcaemia
10.Polyuria
11.Dry mouth
12.Delirium
13.Confusion

Contra-indications of Calcium

1.Renal calculi
2.Hypophosphataemia
3.Hypercalcaemia
4.Ventricular fibrillation.

Special Precautions while taking Calcium

1.Renal impairment
2.Cardiac diseases
3.Sarcoidosis
4.Cor pulmonale
5.Respiratory acidosis
6.Respiratory failure
7.End stage renal failure
8.Hypoparathyroid patients
9.Digitalized patients
10.Prolonged use of therapeutic amounts.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Calcium

1.Hypocalcaemia
2.Calcium and vitamin D deficiency
3.Calcium deficiency during pregnancy and lactation
4.Rickets
5.Prevention of osteoporosis in postmenopausal women
6.Chronic renal failure.

Interactions for Calcium

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Typical Dosage for Calcium

Oral: 500mg to 2g daily in two to four divided doses.
Hypocalcaemia:
Adults: 1g daily. Increases to 2g daily if required.
Prevention of osteoporosis: 1 to 1.5g daily.
Children: 45 to 65mg/kg daily.
Neonates: 50 to 150mg/kg and should not exceed 1g.

Schedule of Calcium

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Storage Requirements for Calcium

Store in a well closed container in a cool and dry place. Protect from light.

Effects of Missed Dosage of Calcium

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Calcium

Remove calcium from stomach by induced emesis and gastric lavage. Provide symptomatic treatment and supportive measures.

Calcitriol

About Calcitriol

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Mechanism of Action of Calcitriol

Calcitriol is a 1, 25-dihydroxycholecalciferol or a Vitamin D analogue. It increases the absorption of Calcium from intestine by forming a calcium binding protein. It reverses the signs of rickets and osteomalacia.

Pharmacokinets of Calcitriol

Absorption: It is readily absorbed after oral administration. Distribution: It is widely distributed in protein bound form. Metabolism: It undergoes metabolism in the liver and kidney. Excretion: It is excreted mainly in the faeces.

Onset of Action for Calcitriol

2 - 6 hours

Duration of Action for Calcitriol

3 - 5 days

Half Life of Calcitriol

3 - 8 hours

Side Effects of Calcitriol

1. Nausea
2. Vomiting
3. Constipation
4. Headache
5. Somnolence
6. Weakness
7. Hypertension
8. Bone and muscle pain
9. Pruritus
10. Weight loss
11. Polyuria
12. Metallic taste
13. Anorexia
14. Dry mouth

Contra-indications of Calcitriol

1. Hypercalcaemia
2. Metastatic calcification
3. Plasma phosphorus level greater than 6 mg/dl

Special Precautions while taking Calcitriol

1.Liver impairment
2.Renal impairment
3.Monitor plasma calcium and creatinine in patients receiving high doses

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Calcitriol

1.Management of Hypocalcaemia
2.Management of hypoparathyroidism and pseudohypoparathyroidism

Interactions for Calcitriol

N/A

Typical Dosage for Calcitriol

Adult:
Oral:
Management of hypocalcaemia:0.25mcg/day.Dosage can be increased by 0.25mcg/day at 1 - 2 month interval.Maintenance dose:0.25 - 1 mcg/ day.
Management of hypoparathyroidism and psedohypothyroidism:0.25mcg/day in the morning and dosage can be incresed at 2 - 4 week intervals.Maintenance dose: 0.5 - 2 mcg/day
Children:above 6 years:same as adult dose
Children 1 - 5 years: 0.25 - 0.75mcg/day

Schedule of Calcitriol

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Storage Requirements for Calcitriol

Store in a well closed container.Protect from heat,light and moisture.Keep out of the reach of children.

Effects of Missed Dosage of Calcitriol

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.Continue the regular schedule.

Effects of Overdose of Calcitriol

Give supportive mesures and symptomatic treatment.

Home Delivery for Zinc oxide + Magnesium + Calcium + Calcitriol in Your City

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Zinc oxide + Magnesium + Calcium + Calcitriol is a generic medicine name and there are several brands available for it. Some of the brands for zinc oxide + magnesium + calcium + calcitriol might be better known than zinc oxide + magnesium + calcium + calcitriol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have zinc oxide + magnesium + calcium + calcitriol in stock, you can ask for one of the branded alternatives for zinc oxide + magnesium + calcium + calcitriol.