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- Pharmacology For Chlorhexidine + Chlorobutanol
Chlorhexidine + Chlorobutanol Pharmacology
Chlorhexidine + Chlorobutanol
About Chlorhexidine + ChlorobutanolN/AMechanism of Action of Chlorhexidine + ChlorobutanolN/APharmacokinets of Chlorhexidine + ChlorobutanolN/AOnset of Action for Chlorhexidine + ChlorobutanolN/ADuration of Action for Chlorhexidine + ChlorobutanolN/AHalf Life of Chlorhexidine + ChlorobutanolN/ASide Effects of Chlorhexidine + ChlorobutanolN/AContra-indications of Chlorhexidine + ChlorobutanolN/ASpecial Precautions while taking Chlorhexidine + ChlorobutanolN/APregnancy Related InformationSince chlorhexidine contraindicated, the combination generic contraindicatedOld Age Related InformationN/ABreast Feeding Related InformationSince chlorhexidine contraindicated, the combination generic contraindicatedChildren Related InformationN/AIndications for Chlorhexidine + ChlorobutanolGingivitisInteractions for Chlorhexidine + ChlorobutanolN/ATypical Dosage for Chlorhexidine + ChlorobutanolRinse mouth with 10 ml of a 0.2% soln for 1 minute bid-tidSchedule of Chlorhexidine + ChlorobutanolN/AStorage Requirements for Chlorhexidine + ChlorobutanolStore at room temperature.Do not freezeEffects of Missed Dosage of Chlorhexidine + ChlorobutanolN/AEffects of Overdose of Chlorhexidine + ChlorobutanolN/AChlorhexidine
About ChlorhexidineA bisbiguanide antimicrobial agent, Anti-infective, antiseptic.Mechanism of Action of ChlorhexidineThis drug has positive charge so it attach to the negative charge cell wall. This destabilizes and destroys the integrity and penetrates bacterial cell membranes. It results precipitation of the cytoplasm and interferes with membrane function by inhibiting oxygen utilization leading to a decrease in cellular ATP levels and cell death. In gram-negative bacteria, chlorhexidine affects the outer membrane allowing the release of periplasmic enzymes. The inner membrane of these organisms is not ruptured but the uptake of small molecules is impaired. At low concentrations chlorhexidine exhibits a bacteriostatic effect while at high concentrations it is bactericidal.Pharmacokinets of ChlorhexidineAbsorption- Poorly from the gastrointestinal tract.
Distribution- 87% bound to the plasma proteins.
Excretion- Excreted through feces.
Onset of Action for ChlorhexidineN/ADuration of Action for ChlorhexidineN/AHalf Life of ChlorhexidineN/ASide Effects of Chlorhexidine1. Bleeding
2. Tender
3. Enlarged gums
4. Cough
5. Congestion or tightness in chest
6. Wheezing
7. Staining of teeth
8. Calculus formation above the gum line
Contra-indications of Chlorhexidine1. Hypersensitivity to the drugSpecial Precautions while taking Chlorhexidine1. Avoid eating or drinking for at least 1 hour after each dose
2. To minimize the staining apply drug with the hollow cup brush tip of the Rota-dent perio tool to only the gum tissue, especially focus on the areas with pockets depths over 4mm
3. You may also alternate drug with custom bleaching trays at home
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Chlorhexidine1. Gingivitis
2. Acute and chronic otitis externa (ear infection/inflammation)
3. Periodontal disease
4. Superficial skin infections
5. Irrigation (cleansing) of wounds and as a medicated shampoo for the treatment of certain skin conditions (hot spots or acute moist dermatitis
Interactions for ChlorhexidineN/ATypical Dosage for ChlorhexidineOral rinse solutions - 0.1 percent.
Otic (ear) solutions - 1 percent.
Chlorhexidine solutions - 2 percent.
Chlorhexidine shampoo and conditioner 1 and 2 percent.
As an ear-cleansing agent - flush the ear canal once a day in cases of diagnosed otitis externa.
For skin conditions - clean the area twice daily.
For gingivitis - Chlorhexidine oral solution is applied as directed once a day. In the morning brush and floss for 2 minutes and than rinse with Chlorhexidine for 30 seconds.
Use 1/2 fl. oz. of undiluted. Swish in mouth for 30 seconds. After rinsing for 30 seconds be sure to spit out all the rinse, do NOT swallow any of the rinse. To minimize medicinal taste, DO NOT rinse with water immediately after use. In the evening brush and floss and rinse again for 30 seconds.
Chlorhexidine shampoo and conditioner - once or twice a week.
Pellet (extended-release), Periochip (in a biodegradable matrix of hydrolyzed gelatin cross-linked with glutaraldehyde), Cream, Dressing, Gel, Lotion, Ointment, Sponge forms are also available.
Schedule of ChlorhexidineN/AStorage Requirements for ChlorhexidineStore at room temperature below 77 degree F. Do not freeze.Effects of Missed Dosage of ChlorhexidineTake any missed dose as soon as possible but not if it is almost time for the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.Effects of Overdose of ChlorhexidineGive symptomatic and supportive treatment.Chlorobutanol
About ChlorobutanolAntibacterial, Antifungal, PreservativeMechanism of Action of ChlorobutanolN/APharmacokinets of ChlorobutanolN/AOnset of Action for ChlorobutanolN/ADuration of Action for ChlorobutanolN/AHalf Life of ChlorobutanolN/ASide Effects of Chlorobutanol1.Hypersensitivity reaction
2.CNS depression
Contra-indications of ChlorobutanolHypersensitivity to the drugSpecial Precautions while taking ChlorobutanolN/APregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Chlorobutanol1.Preservative
2.Anaesthetic
Interactions for ChlorobutanolN/ATypical Dosage for ChlorobutanolN/ASchedule of ChlorobutanolN/AStorage Requirements for ChlorobutanolStore below 30 degree celcius. Do not freeze. Protect from sunlight, moisture and heatEffects of Missed Dosage of ChlorobutanolN/AEffects of Overdose of ChlorobutanolN/AHome Delivery for Chlorhexidine + Chlorobutanol in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including chlorhexidine + chlorobutanol.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for chlorhexidine + chlorobutanol and other medicines and health products. Home delivery services for chlorhexidine + chlorobutanol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take chlorhexidine + chlorobutanol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for chlorhexidine + chlorobutanol before they complete the sale. You can get this information while placing the order for chlorhexidine + chlorobutanol with the pharmacy.
Chlorhexidine + Chlorobutanol is a generic medicine name and there are several brands available for it. Some of the brands for chlorhexidine + chlorobutanol might be better known than chlorhexidine + chlorobutanol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have chlorhexidine + chlorobutanol in stock, you can ask for one of the branded alternatives for chlorhexidine + chlorobutanol.