Edrophonium Pharmacology

Edrophonium

About Edrophonium
Reversible Acetylcholinesterase inhibitor, Anti dote for curare
Mechanism of Action of Edrophonium
Inhibits destruction of acetylcholine by acetylcholinesterase. This facilitates transmission of impulses across myoneural junction and results in increased cholinergic responses such as miosis, increased tonus of intestinal and skeletal muscles, bronchial and ureteral constriction, bradycardia, and increased salivary and sweat gland secretions
Pharmacokinets of Edrophonium
Absorption: Rapidly absorbed
Distribution: Widely distributed to the body
Metabolism; Metabolised in the liver
Excretion: Excreted through urine
Onset of Action for Edrophonium
IM: 2 TO 10 mts.
IV: 30 TO 60 sec
Duration of Action for Edrophonium
IM: 5 to 30 mts
IV: 10 mts
Half Life of Edrophonium
1.8 hrs
Side Effects of Edrophonium
1.Cardiac Arrhythmias
2.Hypotension
3.Bradycardia
4.Respiratory failure
5.Nausea
6.Vomiting
7.Abdominal cramps
8.Allergic reactions
9.Salivation
Contra-indications of Edrophonium
1.Hypersensitivity
2.Intestinal obstruction
3.Urinary obstruction
Special Precautions while taking Edrophonium
1.Asthma
2.Seizure disorder
3.Heart disease
4.Thyroid disorder
5.Intestinal disorder
6.Peptic ulcer
7.Urinary problem
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Edrophonium
1.Myasthenia Gravis Diagnosis
2.Reversal of Nondepolarizing Neuromuscular Blockage
Interactions for Edrophonium
Corticosteroids: Diminish the therapeutic effect of anticholinesterase
Succinylcholine: Prolonged neuromuscular blockade and respiratory depression may occur
Typical Dosage for Edrophonium
As recommended by the physician
Schedule of Edrophonium
N/A
Storage Requirements for Edrophonium
Store at room temperature. Protect from sunlight. Keep out of the reach of children
Effects of Missed Dosage of Edrophonium
N/A
Effects of Overdose of Edrophonium
N/A

Home Delivery for Edrophonium in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including edrophonium.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for edrophonium and other medicines and health products. Home delivery services for edrophonium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take edrophonium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for edrophonium before they complete the sale. You can get this information while placing the order for edrophonium with the pharmacy.

Edrophonium is a generic medicine name and there are several brands available for it. Some of the brands for edrophonium might be better known than edrophonium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have edrophonium in stock, you can ask for one of the branded alternatives for edrophonium.