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- Pharmacology For Budesonide Inhalers + Formoterol Inhalers
Budesonide Inhalers + Formoterol Inhalers Pharmacology
Budesonide Inhalers + Formoterol Inhalers
About Budesonide Inhalers + Formoterol InhalersN/AMechanism of Action of Budesonide Inhalers + Formoterol InhalersN/APharmacokinets of Budesonide Inhalers + Formoterol InhalersN/AOnset of Action for Budesonide Inhalers + Formoterol InhalersN/ADuration of Action for Budesonide Inhalers + Formoterol InhalersN/AHalf Life of Budesonide Inhalers + Formoterol InhalersN/ASide Effects of Budesonide Inhalers + Formoterol InhalersN/AContra-indications of Budesonide Inhalers + Formoterol InhalersN/ASpecial Precautions while taking Budesonide Inhalers + Formoterol InhalersN/APregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Budesonide Inhalers + Formoterol Inhalers1.Asthma
2.COPD
Interactions for Budesonide Inhalers + Formoterol InhalersItraconazole, Clarithromycin, Erythromycin: May inhibit the metabolism of budesonideTypical Dosage for Budesonide Inhalers + Formoterol InhalersPer inhalation contains budesonide(mcg)/formoterol fumarate(mcg) 80/4.5 or 160/4.5 2 inhalations twice dailySchedule of Budesonide Inhalers + Formoterol InhalersN/AStorage Requirements for Budesonide Inhalers + Formoterol InhalersStore it room temperature and away from excess heat and moisture.Keep out of the reach of childrenEffects of Missed Dosage of Budesonide Inhalers + Formoterol InhalersN/AEffects of Overdose of Budesonide Inhalers + Formoterol InhalersN/ABudesonide Inhalers
About Budesonide InhalersInhaled glucocorticoid (Oral), Antiasthmatic, anti-inflammatory.Mechanism of Action of Budesonide InhalersThis corticosteroids act inside the body`s cells to decrease the release of certain chemicals (mast cells, eosinophils, neutrophils, macrophages, and lymphocytes, histamine, eicosanoids, leukotrienes, and cytokines) that are involved in the immune system, and which initiate an inflammatory reaction. Thus it reduces inflammation. In asthma, the airways tighten due to inflammation and can also be blocked by mucus. This makes it difficult for air to get into and out of the lungs. By preventing the inflammation and excess mucus formation, budesonide helps prevent asthmaPharmacokinets of Budesonide InhalersAbsorption- Poorly absorbed after inhalation
Distribution- Widely distributed in the body. 88% bound to the plasma proteins.
Metabolism - Rapidly and extensively metabolized in the liver to its metabolites.
Excretion- Excreted through urine and feces
Onset of Action for Budesonide Inhalers24 hrsDuration of Action for Budesonide InhalersN/AHalf Life of Budesonide InhalersN/ASide Effects of Budesonide Inhalers1. Dry or irritated mouth or throat
2. Cough
3. Painful speech
4. Dizziness
5. Difficulty falling asleep
6. Neck pain
7. Stomach pain
8. Vision problems
9. White spots or sores in your mouth
10. Swollen face, lower legs, or ankles
11. Cold or infection that lasts a long time
12. Muscle weakness
13. Increased difficulty in breathing
14. Skin rash
15. Unusual bleeding or bruising
16. Fever
17. Pain during urination
18. Muscle aches
Contra-indications of Budesonide Inhalers1. Hypersensitivity to the drug.
2. Active tuberculosis infection of the lungs
Special Precautions while taking Budesonide Inhalers1. Fungal or viral infections of the airways.
2. Inactive or dormant tuberculosis infection of the lungs
Pregnancy Related InformationUse with caution.Old Age Related InformationUse with caution.Breast Feeding Related InformationUse with caution.Children Related InformationUse with caution.Indications for Budesonide InhalersAsthma.Interactions for Budesonide InhalersN/ATypical Dosage for Budesonide InhalersIntranasal-
Adults and children (>6yrs)-
256mcg/day. 2 sprays in each nostril and evening or 4 sprays in the morning- Allergic rhinitis and non allergic rhinitis
Oral inhalation-
Adult-
Chronic asthma: 200-400 mcg two times daily
Children- Same as adult.
Schedule of Budesonide InhalersHStorage Requirements for Budesonide InhalersStore it at room temperature and away from excess heat and moisture.Effects of Missed Dosage of Budesonide InhalersTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Budesonide InhalersGive symptomatic and supportive treatment.Formoterol Inhalers
About Formoterol InhalersSelective long-acting ?2- Adrenergic agonist, Phenethylamine derivative.Antiasthmatic.Mechanism of Action of Formoterol InhalersThis ?2 agonist acts locally in the lung as a bronchodilator. It stimulates adenyl cyclase leading to the production of cyclic adenosine monophosphate (cAMP) via adenosine triphosphate (ATP). Increased levels of cAMP result in relaxation of the bronchial smooth muscle.Pharmacokinets of Formoterol InhalersAbsorption- Rapidly absorbed after oral inhalation
Distribution- Widely distributed in the lungs. 61%-64% bound to the plasma proteins
Metabolism- Metabolized primarily by direct glucoronidation at either the phenolic or aliphatic hydroxyl group and O-demethylation followed by glucoronide conjugation at phenolic hydroxyl groups. Minor pathways involve sulfate conjugation of formoterol and deformylation followed by sulfate conjugation
Excretion- Excreted through urine and feces
Onset of Action for Formoterol InhalersN/ADuration of Action for Formoterol Inhalers12 hrsHalf Life of Formoterol InhalersIts plasma half life is 10 hrsSide Effects of Formoterol Inhalers1. Chest pain
2. Pounding heartbeats
3. Tremors
4. Shaking
5. Restless feeling
6. Wheezing
7. Choking
8. Breathing problems
9. Increased thirst or hunger
10. Urinating
11. Worsening asthma symptoms
12. Dizziness
13. Anxiety
14. Headache
15. Sleep problems (insomnia)
16. Back pain
17. Muscle cramps
18. Sore throat
19. Dry mouth
20. Cough
21. Stuffy nose
22. Skin rash
23. Itching
24. Changes in your voice
Contra-indications of Formoterol Inhalers1. Hypersensitivity to the drug
2. Food allergy
3. Heart disease
4. High blood pressure
5. Epilepsy
6. Diabetes
7. Thyroid disorder
Special Precautions while taking Formoterol InhalersN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Formoterol Inhalers1. Chronic asthma
2. Chronic obstructive pulmonary disease (COPD)
Interactions for Formoterol InhalersN/ATypical Dosage for Formoterol InhalersOral inhalation-
Adult-
12mcg taken twice daily
Schedule of Formoterol InhalersN/AStorage Requirements for Formoterol InhalersStore it at room temperature and away from excess heat and moistureEffects of Missed Dosage of Formoterol InhalersTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Formoterol InhalersGive symptomatic and supportive treatmentHome Delivery for Budesonide Inhalers + Formoterol Inhalers in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including budesonide inhalers + formoterol inhalers.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for budesonide inhalers + formoterol inhalers and other medicines and health products. Home delivery services for budesonide inhalers + formoterol inhalers may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take budesonide inhalers + formoterol inhalers only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for budesonide inhalers + formoterol inhalers before they complete the sale. You can get this information while placing the order for budesonide inhalers + formoterol inhalers with the pharmacy.
Budesonide Inhalers + Formoterol Inhalers is a generic medicine name and there are several brands available for it. Some of the brands for budesonide inhalers + formoterol inhalers might be better known than budesonide inhalers + formoterol inhalers itself. If the pharmacy that's willing to deliver medicines to your home doesn't have budesonide inhalers + formoterol inhalers in stock, you can ask for one of the branded alternatives for budesonide inhalers + formoterol inhalers.