Adalimumab Pharmacology

Adalimumab

About Adalimumab
Immunosuppressants, Human Monoclonal Antibody, Anti Rheumatic drug
Mechanism of Action of Adalimumab
Adalimumab is a recombinant DNA-derived human Ig G1 monoclonal antibody. It binds to human tumor necrosis factor alpha (TNF-?), thus interfering with cytokine-driven inflammatory processes
Pharmacokinets of Adalimumab
Absorption: Absorbed after SC administration
Distribution: Widely distributed to the body
Excretion: Excreted mainly through urine
Onset of Action for Adalimumab
N/A
Duration of Action for Adalimumab
N/A
Half Life of Adalimumab
10 to 20 days
Side Effects of Adalimumab
1.Hyperlipidaemia
2.Hypercholesterolaemia
3.Hypokalaemia
4.Hyperuricaemia
5.Headache
6.Drowsiness
7.Dizziness
8.Agitation
9.Tremor
10.Urinary frequency
Contra-indications of Adalimumab
Hypersensitivity
Special Precautions while taking Adalimumab
1.Hepatic impairment
2.Renal impairment
3.Heart failure
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Adalimumab
1.Rheumatoid arthritis
2.Ankylosing spondylitis
3.Crohn?s disease
4.Psoriatic arthritis
5.Ulcerative colitis
Interactions for Adalimumab
Avoid concomitant use of adalimumab with anakinra and live vaccines
Typical Dosage for Adalimumab
Dose for Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic disease: 40 mg every other wk
Dose for Crohn?s disease: 40 mg every other wk. For severe active disease: Initially, 160 mg given as 4 divided doses over 1-2 days, then 80 mg 2 wk after the initial dose.
Maintenance: 40 mg every other wk; may increase to 40 mg wkly if needed
Schedule of Adalimumab
N/A
Storage Requirements for Adalimumab
Store between 2 to 8 degree celcius.Keep out of the reach of children
Effects of Missed Dosage of Adalimumab
N/A
Effects of Overdose of Adalimumab
N/A

Home Delivery for Adalimumab in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including adalimumab.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for adalimumab and other medicines and health products. Home delivery services for adalimumab may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take adalimumab only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for adalimumab before they complete the sale. You can get this information while placing the order for adalimumab with the pharmacy.

Adalimumab is a generic medicine name and there are several brands available for it. Some of the brands for adalimumab might be better known than adalimumab itself. If the pharmacy that's willing to deliver medicines to your home doesn't have adalimumab in stock, you can ask for one of the branded alternatives for adalimumab.