Triamcinolone acetonide Mouth Paste Pharmacology

Triamcinolone acetonide Mouth Paste

About Triamcinolone acetonide Mouth Paste
A synthetic glucocorticoid, In mouth sores.
Mechanism of Action of Triamcinolone acetonide Mouth Paste
The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows its migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts more selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-a, GM-CSF (granulocyte macrophage colony stimulating factor), Gamma interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Triamcinolone acetonide paste forms a protective film over the mouth ulcer. It protects the tissue from further damage.
Pharmacokinets of Triamcinolone acetonide Mouth Paste
N/A
Onset of Action for Triamcinolone acetonide Mouth Paste
N/A
Duration of Action for Triamcinolone acetonide Mouth Paste
N/A
Half Life of Triamcinolone acetonide Mouth Paste
N/A
Side Effects of Triamcinolone acetonide Mouth Paste
1.Dryness
2.Rash
3.Hives
4.Itching
Contra-indications of Triamcinolone acetonide Mouth Paste
1.Hypersensitivity to Triamcinolone acetonide paste
2.Fungal, viral, or bacterial infection of the mouth or throat
3.Recent vaccination
Special Precautions while taking Triamcinolone acetonide Mouth Paste
N/A
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Triamcinolone acetonide Mouth Paste
Mouth sores
Interactions for Triamcinolone acetonide Mouth Paste
N/A
Typical Dosage for Triamcinolone acetonide Mouth Paste
Apply the medicament at bed time and if needed repeat 2 - 3 times daily preferably after meals.
Schedule of Triamcinolone acetonide Mouth Paste
N/A
Storage Requirements for Triamcinolone acetonide Mouth Paste
Store in a cool, dry place. Protect from direct heat and light. Keep out of the reach of children
Effects of Missed Dosage of Triamcinolone acetonide Mouth Paste
Take the missed dose as son as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Triamcinolone acetonide Mouth Paste
Give supportive measures and symptomatic treatment.

Home Delivery for Triamcinolone acetonide Mouth Paste in Your City

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Triamcinolone acetonide Mouth Paste is a generic medicine name and there are several brands available for it. Some of the brands for triamcinolone acetonide mouth paste might be better known than triamcinolone acetonide mouth paste itself. If the pharmacy that's willing to deliver medicines to your home doesn't have triamcinolone acetonide mouth paste in stock, you can ask for one of the branded alternatives for triamcinolone acetonide mouth paste.