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- Pharmacology For Iodine + Potassium iodide + Tannic Acid
Iodine + Potassium iodide + Tannic Acid Pharmacology
Iodine + Potassium iodide + Tannic Acid
About Iodine + Potassium iodide + Tannic AcidN/AMechanism of Action of Iodine + Potassium iodide + Tannic AcidN/APharmacokinets of Iodine + Potassium iodide + Tannic AcidN/AOnset of Action for Iodine + Potassium iodide + Tannic AcidN/ADuration of Action for Iodine + Potassium iodide + Tannic AcidN/AHalf Life of Iodine + Potassium iodide + Tannic AcidN/ASide Effects of Iodine + Potassium iodide + Tannic AcidN/AContra-indications of Iodine + Potassium iodide + Tannic AcidN/ASpecial Precautions while taking Iodine + Potassium iodide + Tannic AcidN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Iodine + Potassium iodide + Tannic AcidN/AInteractions for Iodine + Potassium iodide + Tannic AcidN/ATypical Dosage for Iodine + Potassium iodide + Tannic AcidN/ASchedule of Iodine + Potassium iodide + Tannic AcidN/AStorage Requirements for Iodine + Potassium iodide + Tannic AcidN/AEffects of Missed Dosage of Iodine + Potassium iodide + Tannic AcidN/AEffects of Overdose of Iodine + Potassium iodide + Tannic AcidN/AIodine
About IodineEssential trace element, fastest acting thyroid inhibitor, Antithyroid agent.Mechanism of Action of IodineIt is the fastest acting thyroid inhibitor which inhibits hormone release. It reduced to iodide response to both iodine and iodides are identical. Endocytosis of colloid and proteolysis of thyroglobulin comes to a halt. It has a direct action on thyroid cells and also attenuate TSH and cyclic AMP induced thyroid stimulation. Excess iodide inhibits it`s on transport in thyroid cells and alter the redox potential of cells; thus interfering with iodination and reduces T3 or T4 synthesis. The gland if enlarged; shrinks, becomes firm and less vascular. The thyroid status returns to normal at a faster rate.Pharmacokinets of IodineAbsorption: Well absorbed orally.
Distribution: Widely distributed in the body and also crosses the placenta.
Onset of Action for IodineN/ADuration of Action for IodineN/AHalf Life of IodineN/ASide Effects of Iodine1. Fever
2. Angioedema
3. Swelling of lips and eyelids
4. Arthralgia
5. Thrombocytopenia
6. Salivation
7. Sneezing
8. Lymphadenopathy
9. Petechial haemorrhage.
10. Burning sensation in mouth
11. Headache
12. Rashes
13. Flaring of acne
Contra-indications of Iodine1. Hypersensitivity to the drugSpecial Precautions while taking Iodine1. Long term therapy with high dosePregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Iodine1. Hyperthyroidism
2. Hypothyroidism
3. Prior to thyroidectomy
4. Prophylaxis of endemic goiter
Interactions for IodineN/ATypical Dosage for IodineOral: 5 to 10ml in water 8th hourly.Schedule of IodineHStorage Requirements for IodineStore in a well closed container and protects from light.Effects of Missed Dosage of IodineTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of IodineProvide symptomatic treatment and supportive measures.
Potassium Iodide
About Potassium IodideN/AMechanism of Action of Potassium IodideIt works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.Pharmacokinets of Potassium IodideN/AOnset of Action for Potassium IodideN/ADuration of Action for Potassium IodideN/AHalf Life of Potassium IodideN/ASide Effects of Potassium Iodide1.Nausea
2.Vomiting
3.Upset stomach, or stomach pain
4.Mild skin rash
5.A metallic taste in the mouth.
Contra-indications of Potassium IodideN/ASpecial Precautions while taking Potassium IodideN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Potassium Iodide1.Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
2.To protect the thyroid gland from radiation injury before and following administration of radioactive iodide (e.g., for diagnostic purposes) and in radiation emergencies (e.g., accidental exposure to radiation).
3.Chronic respiratory problems such as asthma, chronic bronchitis, and emphysema(expectorant).
4.Component of some eye drops.
5.Antifungal: Cutaneous Sporotrichosis is a fungus that can cause lesions on the skin. A saturated solution of potassium iodide can be used to treat the lesion.
Interactions for Potassium IodideN/ATypical Dosage for Potassium IodideUsual Adult Dose for Cough:300 to 650 mg orally 3 to 4 times a day.
Usual Adult Dose for Hyperthyroidism:
Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.
Usual Adult Dose for Cutaneous Sporotrichosis:250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 2 to 2.5 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.
Usual Adult Dose for Radiation Emergency:
Pregnant or lactating women with exposure >= 5 centigrays (cGy): 130 mg orally per day.
>18 and <=40 years with exposure >= 10 centigrays (cGy): 130 mg orally per day.
>40 years with exposure >= 500 centigrays (cGy): 130 mg orally per day.
Usual Pediatric Dose for Cough:60 to 250 mg orally every 4 to 6 times a day.
Usual Pediatric Dose for Hyperthyroidism:Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.
Usual Pediatric Dose for Cutaneous Sporotrichosis:250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 1.25 to 2 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.
Usual Pediatric Dose for Radiation Emergency:
<=1 month with exposure >= 5 centigrays (cGy): 16 mg orally per day.
>1 month <=3 years with exposure >= 5 centigrays (cGy): 32 mg orally per day.
>3 years <= 18 years (less than 70 kg) with exposure >= 5 centigrays (cGy): 65 mg orally per day.
>13 years >= 70 kg with exposure >= 5 centigrays (cGy): 130 mg orally per day.
Schedule of Potassium IodideN/AStorage Requirements for Potassium IodideN/AEffects of Missed Dosage of Potassium IodideN/AEffects of Overdose of Potassium IodideN/ATannic acid
About Tannic acidN/AMechanism of Action of Tannic acidTannic acid has anti-bacterial, anti-enzymatic and astringent properties. The anti-oxidant and anti-mutagenic properties of tannic acid are beneficial. Tannic Acid is used in dental preparation due to its astringent action. It helps in shrinking the swollen mucosa and heals ulcer faster.Pharmacokinets of Tannic acidN/AOnset of Action for Tannic acidN/ADuration of Action for Tannic acidN/AHalf Life of Tannic acidN/ASide Effects of Tannic acidMild tingling sensationContra-indications of Tannic acidN/ASpecial Precautions while taking Tannic acidN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Tannic acidN/AInteractions for Tannic acidN/ATypical Dosage for Tannic acidN/ASchedule of Tannic acidN/AStorage Requirements for Tannic acidN/AEffects of Missed Dosage of Tannic acidN/AEffects of Overdose of Tannic acidN/AHome Delivery for Iodine + Potassium iodide + Tannic Acid in Your City
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