Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium Pharmacology

Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

About Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Mechanism of Action of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Pharmacokinets of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Onset of Action for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Duration of Action for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Half Life of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Side Effects of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Contra-indications of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Special Precautions while taking Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Pregnancy Related Information

Use with caution

Old Age Related Information

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Breast Feeding Related Information

Use with caution

Children Related Information

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Indications for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

Antioxidant

Interactions for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Typical Dosage for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

1 capsule / day

Schedule of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Storage Requirements for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Effects of Missed Dosage of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Effects of Overdose of Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium

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Co Enzyme Q10

About Co Enzyme Q10

1,4-benzoquinone derivative, oil-soluble vitamin-like substance, Enzyme cofactors, powerful antioxidant

Mechanism of Action of Co Enzyme Q10

Coenzyme Q10 is vital for the proper transfer of electrons within the mitochondrial oxidative respiratory chain there it passes reducing equivalents to acceptors such as Coenzyme Q: cytochrome c - oxidoreductase:
CoQH2+ 2 FeIII-cytochrome c ? CoQ + 2 FeII-cytochrome c. main function of this transport is adenosine triphosphate production. Coenzyme Q10 also increases adenosine triphosphate levels by preventing the loss of the adenine nucleotide pool from cardiac cells. Coenzyme Q10 has activity as an antioxidant scavenger and an indirect stabilizer of calcium channels to decrease calcium overload. It also inhibits the oxidation of LDL-cholesterol. LDL-cholesterol oxidation is believed to play a significant role in the pathogenesis of atherosclerosis.

Pharmacokinets of Co Enzyme Q10

Absorption- Poorly absorbed after oral administration. Excretion- Excreted through bile and feces

Onset of Action for Co Enzyme Q10

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Duration of Action for Co Enzyme Q10

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Half Life of Co Enzyme Q10

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Side Effects of Co Enzyme Q10

1. Nausea
2. Vomiting
3. Stomach upset
4. Heartburn
5. Diarrhea
6. Loss of appetite
7. Skin itching
8. Rash
9. Insomnia
10. Headache
11. Dizziness
12. Irritability
13. Increased light sensitivity of the eyes
14. Fatigue
15. Flu-like symptoms

Contra-indications of Co Enzyme Q10

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Special Precautions while taking Co Enzyme Q10

N/A

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Co Enzyme Q10

1. Dietary supplement
2. Antioxidant
3. Migraine headaches
4. Parkinson`s Disease
5. Mitochondrial Encephalomyopathies
6. Migraine
7. CHF
8. Hypertension
9. Diabetes
10. Cancer

Interactions for Co Enzyme Q10

N/A

Typical Dosage for Co Enzyme Q10

Adult-
Oral-
Mitochondrial cytopathies: 150 mg per day or 2 mg per kg per day with titration up to 3,000 mg per day in some patients
Parkinson`s disease: 300 to 1,200 mg per day in four divided doses
Cardiovascular problems: 50 to 200 mg per day
Migraine 100 to 200 mg per day

Schedule of Co Enzyme Q10

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Storage Requirements for Co Enzyme Q10

Keep tightly closed in a dry place. Do not expose to excessive heat.

Effects of Missed Dosage of Co Enzyme Q10

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.Continue the regular schedule.

Effects of Overdose of Co Enzyme Q10

Give supportive measures and symptomatic treatment.

Vitamin E

About Vitamin E

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Mechanism of Action of Vitamin E

Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.

Pharmacokinets of Vitamin E

Absorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.

Onset of Action for Vitamin E

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Duration of Action for Vitamin E

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Half Life of Vitamin E

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Side Effects of Vitamin E

1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence

Contra-indications of Vitamin E

1. Hypersensitivity to the drug
2. Should not administer intravenously

Special Precautions while taking Vitamin E

1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens

Pregnancy Related Information

May be used

Old Age Related Information

N/A

Breast Feeding Related Information

May be used

Children Related Information

N/A

Indications for Vitamin E

1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant

Interactions for Vitamin E

Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.

Typical Dosage for Vitamin E

Oral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.

Schedule of Vitamin E

Storage Requirements for Vitamin E

Store in a well closed container in a cool dry place. Protect from light.

Effects of Missed Dosage of Vitamin E

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Vitamin E

Provide supportive measures and symptomatic treatment.

Zinc

About Zinc

Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.

Mechanism of Action of Zinc

Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.

Pharmacokinets of Zinc

Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.

Onset of Action for Zinc

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Duration of Action for Zinc

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Half Life of Zinc

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Side Effects of Zinc

1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes

Contra-indications of Zinc

N/A

Special Precautions while taking Zinc

1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information

Use with caution

Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Zinc

1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia

Interactions for Zinc

Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc

Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.

Schedule of Zinc

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Storage Requirements for Zinc

Store at a temperature below 30 degree C

Effects of Missed Dosage of Zinc

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Zinc

Provide symptomatic treatment and supportive measures

Manganese

About Manganese

Magnesium is essential for enzyme activity, calcium and potassium uptake, nerve transmission, bone formation and metabolism of carbohydrates and minerals. It is magnesium, not calcium, which helps form hard tooth enamel, resistant to decay. Like calcium and chloride, magnesium also plays a role in regulating the acid-alkaline balance in the body. High magnesium levels in drinking water have been linked to resistance to heart disease. Although it is found in many foods, including dairy products, nuts, vegetables, fish, meat and seafood, deficiencies are common in America due to soil depletion, poor absorption and lack of minerals in drinking water. A diet high in carbohydrates, oxalic acid in foods like raw spinach and phytic acid found in whole grains can cause deficiencies. An excellent source of usable magnesium is beef, chicken or fish broth. High amounts of zinc and vitamin D increase magnesium requirements. Magnesium deficiency can result in coronary heart disease, chronic weight loss, obesity, fatigue, epilepsy and impaired brain function. Chocolate cravings are a sign of magnesium deficiency.

Mechanism of Action of Manganese

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Pharmacokinets of Manganese

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Onset of Action for Manganese

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Duration of Action for Manganese

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Half Life of Manganese

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Side Effects of Manganese

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Contra-indications of Manganese

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Special Precautions while taking Manganese

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Manganese

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Interactions for Manganese

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Typical Dosage for Manganese

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Schedule of Manganese

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Storage Requirements for Manganese

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Effects of Missed Dosage of Manganese

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Effects of Overdose of Manganese

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Selenium

About Selenium

A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.

Mechanism of Action of Selenium

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Pharmacokinets of Selenium

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Onset of Action for Selenium

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Duration of Action for Selenium

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Half Life of Selenium

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Side Effects of Selenium

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Contra-indications of Selenium

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Special Precautions while taking Selenium

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Selenium

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Interactions for Selenium

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Typical Dosage for Selenium

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Schedule of Selenium

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Storage Requirements for Selenium

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Effects of Missed Dosage of Selenium

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Effects of Overdose of Selenium

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Home Delivery for Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium in Your City

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Co Enzyme Q10 + Vitamin E + Zinc + Manganese + Selenium is a generic medicine name and there are several brands available for it. Some of the brands for co enzyme q10 + vitamin e + zinc + manganese + selenium might be better known than co enzyme q10 + vitamin e + zinc + manganese + selenium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have co enzyme q10 + vitamin e + zinc + manganese + selenium in stock, you can ask for one of the branded alternatives for co enzyme q10 + vitamin e + zinc + manganese + selenium.